Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Thomas D Lewin"'
Autor:
Thomas D. Lewin, Blandine Avignon, Alessio Tovaglieri, Lauriane Cabon, Nikolche Gjorevski, Lucy G. Hutchinson
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Cancer immunotherapy often involves the use of engineered molecules to selectively bind and activate T cells located within tumour tissue. Fundamental to the success of such treatments is the presence or recruitment of T cells localised within the tu
Externí odkaz:
https://doaj.org/article/fd3e59da22e0471e9e57da377981c377
Publikováno v:
Genome Biology and Evolution.
LEUTX is a homeodomain transcription factor expressed in the very early embryo with a function around embryonic genome activation. The LEUTX gene is found only in eutherian mammals, including humans, but unlike the majority of homeobox genes, the enc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e6dbef7e246e6dc7bfb419ab6d5af9f
https://doi.org/10.1093/gbe/evad097
https://doi.org/10.1093/gbe/evad097
Publikováno v:
Journal of Molecular Evolution
The majority of homeobox genes are highly conserved across animals, but the eutherian-specific ETCHbox genes, embryonically expressed and highly divergent duplicates of CRX, are a notable exception. Here we compare the ETCHbox genes of 34 mammalian s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89dab5ca41c0377e77d543436bb20fb1
https://doi.org/10.1007/s00239-021-10012-6
https://doi.org/10.1007/s00239-021-10012-6
Autor:
Thomas D, Lewin, Blandine, Avignon, Alessio, Tovaglieri, Lauriane, Cabon, Nikolche, Gjorevski, Lucy G, Hutchinson
Publikováno v:
Frontiers in pharmacology. 13
Cancer immunotherapy often involves the use of engineered molecules to selectively bind and activate T cells located within tumour tissue. Fundamental to the success of such treatments is the presence or recruitment of T cells localised within the tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::494c6e725ea0d4522920602b596abf4d
https://pubmed.ncbi.nlm.nih.gov/35586042
https://pubmed.ncbi.nlm.nih.gov/35586042
Autor:
Jimmy J. Caudell, Helen M. Byrne, Eduardo G. Moros, Thomas D. Lewin, Philip K. Maini, Heiko Enderling
Publikováno v:
Physics in Medicine & Biology. 65:015007
In vivo tumours are highly heterogeneous, often comprising regions of hypoxia and necrosis. Radiotherapy significantly alters the intratumoural composition. Moreover, radiation-induced cell death may occur via a number of different mechanisms that ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdbef58c1f3cf4e45b78319829534627
https://doi.org/10.1088/1361-6560/ab4c27
https://doi.org/10.1088/1361-6560/ab4c27
Publikováno v:
Mathematical Modelling of Natural Phenomena. 15:22
In vivo tumours are highly heterogeneous entities which often comprise intratumoural regions of hypoxia and widespread necrosis. In this paper, we develop a new three phase model of nutrient-limited, avascular tumour growth to investigate how dead ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1485ed2964b7925e56665f65f8177c3e
https://doi.org/10.1051/mmnp/2019039
https://doi.org/10.1051/mmnp/2019039
Publikováno v:
Bulletin of mathematical biology. 80(5)
Current protocols for delivering radiotherapy are based primarily on tumour stage and nodal and metastases status, even though it is well known that tumours and their microenvironments are highly heterogeneous. It is well established that the local o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e72e11a11fcd564e2516fc640a31516
https://pubmed.ncbi.nlm.nih.gov/29488054
https://pubmed.ncbi.nlm.nih.gov/29488054
Autor:
Eduardo G. Moros, J.F. Torres-Roca, David I. Rosenthal, J. Heukelom, Louis B. Harrison, Helen M. Byrne, Abdallah S.R. Mohamed, Jimmy J. Caudell, Kujtim Latifi, Thomas D. Lewin, Joshua A. Bull, Heiko Enderling, C.D. Fuller, Robert A. Gatenby, Jan Poleszczuk, Jongphil Kim
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 94:903
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65de209bedfc3ebbd4800e6bee4af5fa
https://doi.org/10.1016/j.ijrobp.2015.12.116
https://doi.org/10.1016/j.ijrobp.2015.12.116