Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Thomas Dümmler"'
Autor:
Michael Steurer, Marco Montillo, Lydia Scarfò, Francesca R. Mauro, Johannes Andel, Sophie Wildner, Livio Trentin, Ann Janssens, Sonja Burgstaller, Anna Frömming, Thomas Dümmler, Kai Riecke, Matthias Baumann, Diana Beyer, Stéphanie Vauléon, Paolo Ghia, Robin Foà, Federico Caligaris-Cappio, Marco Gobbi
Publikováno v:
Haematologica, Vol 104, Iss 10 (2019)
Olaptesed pegol (NOX-A12) is a pegylated structured L-oligoribonucleotide that binds and neutralizes CXCL12, a chemokine tightly regulating the life cycle of chronic lymphocytic leukemia cells. The resulting inhibition of CXCR4 and CXCR7 signaling re
Externí odkaz:
https://doaj.org/article/e87d8b780fc74f3e8d8ce9bfbe956c1b
Autor:
Marco Gobbi, Kai Riecke, Robin Foà, Johannes Andel, Marco Montillo, Lydia Scarfò, Stephanie Vauléon, Anna Frömming, Michael Steurer, Sonja Burgstaller, Paolo Ghia, Francesca Romana Mauro, Sophie Wildner, Thomas Dümmler, Diana Beyer, Ann Janssens, Livio Trentin, Matthias Baumann, Federico Caligaris-Cappio
Publikováno v:
Haematologica
Olaptesed pegol (NOX-A12) is a pegylated structured L-oligoribonucleotide that binds and neutralizes CXCL12, a chemokine tightly regulating the life cycle of chronic lymphocytic leukemia cells. The resulting inhibition of CXCR4 and CXCR7 signaling re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74700fa1e3f1fadba3c191ee7a1172ab
Publikováno v:
Zeitschrift für Entwicklungspsychologie und Pädagogische Psychologie. 41:189-197
Zusammenfassung. Bisherige Arbeiten haben dargelegt, dass sich innerhalb des ersten Lebensjahres ein Wechsel von einer analytischen hin zu einer konfiguralen Verarbeitung von Objekten vollzieht. Dieser Wechsel wird im Wesentlichen als von der Komplex
Autor:
Sophie Wildner, Thomas Dümmler, Francesca Romana Mauro, Ann Janssens, Kai Riecke, Marco Montillo, Sonja Burgstaller, Anna Kruschinski, Lydia Scarfò, Michael Steurer, Federico Caligaris-Cappio, Livio Trentin, Paolo Ghia, Marco Gobbi, Johannes Andel
Publikováno v:
Blood. 124:1996-1996
Background Olaptesed pegol (NOX-A12) is a novel, potent, L-stereoisomer RNA aptamer that binds and neutralizes CXCL12/SDF-1, a chemokine which attracts and activates immune- and non-immune cells via interaction with the receptors CXCR4 and CXCR7. Sig
Autor:
Anna Kruschinski, Richard Greil, Robin Foà, Kai Riecke, Heinz Ludwig, Xavier Leleu, Maria Teresa Petrucci, Anna Maria Cafro, Thomas Dümmler, Garderet Laurent, Ibrahim Yakoub-Agha, Katja Weisel, Niklas Zojer, Monika Engelhardt
Publikováno v:
Blood. 124:2111-2111
Background Olaptesed, an L-stereo-isomer RNA aptamer, binds and neutralizes the chemokine CXCL12. By interaction with the chemokine receptors CXCR4 and CXCR7, CXCL12 is responsible for trafficking and homing of normal and malignant blood cells to the
Publikováno v:
Memorycognition. 33(2)
We conducted two experiments examining children’s and adults’ gaze behavior when processing faces analytically (focusing on a single feature) or holistically (comparing the overall similarity of the faces). Children 6–8 and 9–10 years of age
Autor:
Heinz Ludwig, Anna Maria Cafro, Anna Kruschinski, Katja Weisel, Thomas Dümmler, Maria Teresa Petrucci, Stefan Zöllner, Stefan Zeitler, Kai Riecke, Richard Greil, Monika Engelhardt
Publikováno v:
Blood. 122:1951-1951
Background NOX-A12 is a novel, potent, L-stereoisomer RNA aptamer (Spiegelmer®) that binds and neutralizes CXCL12/SDF-1, a chemokine which attracts and activates immune- and non-immune cells via interaction with its receptors, CXCR4 and CXCR7. CXCL1
Autor:
Thomas Dümmler, Kai Riecke, Stefan Zeitler, Michael Steurer, Ann Janssens, Livio Trentin, Marco Gobbi, Marco Montillo, Federico Caligaris-Cappio, Anna Kruschinski, Stefan Zöllner
Publikováno v:
Blood. 122:1635-1635
Background NOX-A12 is a novel, potent, L-stereoisomer RNA aptamer (Spiegelmer(®)) that binds and neutralizes CXCL12/SDF-1, a chemokine which attracts and activates immune- and non-immune cells via interaction with its receptors, CXCR4 and CXCR7. The
Autor:
Marco Montillo, Marco Gobbi, Thomas Dümmler, Stefan Zöllner, Stephanie Vauléon, Anna Kruschinski, Federico Caligaris-Cappio, Frank Fliegert
Publikováno v:
Blood. 120:4593-4593
Abstract 4593 Background NOX-A12 is a novel, potent, L-aptamer inhibitor of CXCL12/SDF-1, a chemokine which attracts and activates immune- and non-immune cells. The signaling of CXCL12 has been shown to play an important role in the pathophysiology o
Autor:
Malcolm Boyce, Stefan Zöllner, Kai Riecke, Luciana Summo, Dorine W. Swinkels, Frank Schwoebel, Stephanie Vauléon, Frank Fliegert, Coby M. Laarakkers, Thomas Dümmler
Publikováno v:
Blood. 120:2342-2342
Abstract 2342 Background: NOX-H94, the first-in-class hepcidin inhibitor in development for treatment of anemia of chronic disease (ACD), is a PEGylated anti-hepcidin L-RNA oligonucleotide. ACD is caused by iron sequestration in the reticulo-endothel