Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Thomas D, Parker"'
Autor:
Matthew J Cross, Mathew G Wilson, Simon Kemp, Daniel Friedland, David J Sharp, Thomas D Parker, Karl A Zimmerman, Neil S N Graham, Jessica A Hain, Erin Jane Rooney, Ying Lee, Martina Del-Giovane, Richard J Sylvester
Publikováno v:
BMJ Open, Vol 14, Iss 4 (2024)
Introduction Although limited, recent research suggests that contact sport participation might have an adverse long-term effect on brain health. Further work is required to determine whether this includes an increased risk of neurodegenerative diseas
Externí odkaz:
https://doaj.org/article/ab5bc75522d74c1c87e7b35928f1f36c
Autor:
Rebecca E. Green, Jodie Lord, Marzia A. Scelsi, Jin Xu, Andrew Wong, Sarah Naomi-James, Alex Handy, Lachlan Gilchrist, Dylan M. Williams, Thomas D. Parker, Christopher A. Lane, Ian B. Malone, David M. Cash, Carole H. Sudre, William Coath, David L. Thomas, Sarah Keuss, Richard Dobson, Cristina Legido-Quigley, Nick C. Fox, Jonathan M. Schott, Marcus Richards, Petroula Proitsi, The Insight 46 study team
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-13 (2023)
Abstract Background Identifying blood-based signatures of brain health and preclinical pathology may offer insights into early disease mechanisms and highlight avenues for intervention. Here, we systematically profiled associations between blood meta
Externí odkaz:
https://doaj.org/article/f5a5b80764c34bc1b3fd5049c6dcb527
Autor:
William Coath, Marc Modat, M. Jorge Cardoso, Pawel J. Markiewicz, Christopher A. Lane, Thomas D. Parker, Ashvini Keshavan, Sarah M. Buchanan, Sarah E. Keuss, Matthew J. Harris, Ninon Burgos, John Dickson, Anna Barnes, David L. Thomas, Daniel Beasley, Ian B. Malone, Andrew Wong, Kjell Erlandsson, Benjamin A. Thomas, Michael Schöll, Sebastien Ourselin, Marcus Richards, Nick C. Fox, Jonathan M. Schott, David M. Cash, for the Alzheimer's Disease Neuroimaging Initiative
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 15, Iss 2, Pp n/a-n/a (2023)
Abstract INTRODUCTION The Centiloid scale aims to harmonize amyloid beta (Aβ) positron emission tomography (PET) measures across different analysis methods. As Centiloids were created using PET/computerized tomography (CT) data and are influenced by
Externí odkaz:
https://doaj.org/article/89fc878da77c45b0abc21824ecd8a625
Autor:
Christopher A. Lane, Josephine Barnes, Jennifer M. Nicholas, John W. Baker, Carole H. Sudre, David M. Cash, Thomas D. Parker, Ian B. Malone, Kirsty Lu, Sarah-Naomi James, Ashvini Keshavan, Sarah Buchanan, Sarah Keuss, Heidi Murray-Smith, Andrew Wong, Elizabeth Gordon, William Coath, Marc Modat, David Thomas, Rebecca Hardy, Marcus Richards, Nick C. Fox, Jonathan M. Schott
Publikováno v:
Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-19 (2021)
Abstract Background In view of reported associations between high adiposity, particularly in midlife and late-life dementia risk, we aimed to determine associations between body mass index (BMI), and BMI changes across adulthood and brain structure a
Externí odkaz:
https://doaj.org/article/10e2a7dba0b142c4a8c65a142938d773
Autor:
Sarah‐Naomi James, Jennifer M. Nicholas, Christopher A. Lane, Thomas D. Parker, Kirsty Lu, Ashvini Keshavan, Sarah M. Buchanan, Sarah E. Keuss, Heidi Murray‐Smith, Andrew Wong, David M. Cash, Ian B. Malone, Josephine Barnes, Carole H. Sudre, William Coath, Lloyd Prosser, Sebastien Ourselin, Marc Modat, David L. Thomas, Jorge Cardoso, Amanda Heslegrave, Henrik Zetterberg, Sebastian J. Crutch, Jonathan M. Schott, Marcus Richards, Nick C. Fox
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 8, Iss 4, Pp 842-856 (2021)
Abstract Objective To assess associations between head injury (HI) with loss of consciousness (LOC), ageing and markers of later‐life cerebral pathology; and to explore whether those effects may help explain subtle cognitive deficits in dementia‐
Externí odkaz:
https://doaj.org/article/f1db91f3d9084dcca21faecff35979d1
Autor:
Sarah-Naomi James, Christopher A. Lane, Thomas D. Parker, Kirsty Lu, Jessica D. Collins, Heidi Murray-Smith, Michelle Byford, Andrew Wong, Ashvini Keshavan, Sarah Buchanan, Sarah E. Keuss, Diana Kuh, Nick C. Fox, Jonathan M. Schott, Marcus Richards
Publikováno v:
BMC Research Notes, Vol 11, Iss 1, Pp 1-9 (2018)
Abstract Objective Identifying and recruiting people with early pre-symptomatic Alzheimer’s disease to neuroimaging research studies is increasingly important. The extent to which results of these studies can be generalised depends on the recruitme
Externí odkaz:
https://doaj.org/article/ba3b7ef34ae3429e973d5ecddf4dc1ef
Autor:
Ashvini Keshavan, Henrietta Wellington, Zhongbo Chen, Ayesha Khatun, Miles Chapman, Melanie Hart, David M. Cash, William Coath, Thomas D. Parker, Sarah M. Buchanan, Sarah E. Keuss, Matthew J. Harris, Heidi Murray‐Smith, Amanda Heslegrave, Nick C. Fox, Henrik Zetterberg, Jonathan M Schott
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 13, Iss 1, Pp n/a-n/a (2021)
Abstract INTRODUCTION We assessed the concordance of cerebrospinal fluid (CSF) amyloid beta (Aβ) and tau measured on the fully automated Lumipulse platform with pre‐symptomatic Alzheimer's disease (AD) pathology on amyloid positron emission tomogr
Externí odkaz:
https://doaj.org/article/6d192a34b4fb4435b96b930df6feef2f
Autor:
Thomas D. Parker, David M. Cash, Christopher A. Lane, Kirsty Lu, Ian B. Malone, Jennifer M. Nicholas, Sarah‐Naomi James, Ashvini Keshavan, Heidi Murray‐Smith, Andrew Wong, Sarah M. Buchanan, Sarah E. Keuss, Carole H. Sudre, David L. Thomas, Sebastian J. Crutch, Nick C. Fox, Marcus Richards, Jonathan M. Schott
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 12, Iss 1, Pp n/a-n/a (2020)
Abstract Introduction Cortical thickness has been proposed as a biomarker of Alzheimer's disease (AD)– related neurodegeneration, but the nature of its relationship with amyloid beta (Aβ) deposition and white matter hyperintensity volume (WMHV) in
Externí odkaz:
https://doaj.org/article/cd9606478e5d4d4c8b5a8c069934908e
Autor:
Kirsty Lu, Jennifer M. Nicholas, Sarah‐Naomi James, Christopher A. Lane, Thomas D. Parker, Ashvini Keshavan, Sarah E. Keuss, Sarah M. Buchanan, Heidi Murray‐Smith, David M. Cash, Carole H. Sudre, Ian B. Malone, William Coath, Andrew Wong, Susie M.D. Henley, Nick C. Fox, Marcus Richards, Jonathan M. Schott, Sebastian J. Crutch
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 12, Iss 1, Pp n/a-n/a (2020)
Abstract Introduction We investigated whether life‐course factors and neuroimaging biomarkers of Alzheimer's disease pathology predict reaction time (RT) performance in older adults. Methods Insight 46 study participants, all born in the same week
Externí odkaz:
https://doaj.org/article/581b7ddff37a46509cc58782170ae19f
Autor:
Ashvini Keshavan, Henrietta Wellington, Zhongbo Chen, Ayesha Khatun, Miles Chapman, Melanie Hart, David M. Cash, William Coath, Thomas D. Parker, Sarah M. Buchanan, Sarah E. Keuss, Matthew J. Harris, Heidi Murray‐Smith, Amanda Heslegrave, Nick C. Fox, Henrik Zetterberg, Jonathan M. Schott
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 12, Iss 1, Pp n/a-n/a (2020)
Abstract Introduction We assessed the concordance of cerebrospinal fluid (CSF) amyloid beta (Aβ) and tau measured on the fully automated Lumipulse platform with pre‐symptomatic Alzheimer's disease (AD) pathology on amyloid positron emission tomogr
Externí odkaz:
https://doaj.org/article/e0d2b395b65f4dd1afd1a7baf34097a2