Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Thomas Colby"'
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Legionella pneumophila (LP) employs the metaeffector SidJ to suppress the toxicity of SdeA and other LP SidE effector family members by catalysing the glutamylation of the catalytic Glu residue. Here, the authors present the cryo-EM structures of Sid
Externí odkaz:
https://doaj.org/article/330293d1384b47d989742f3a1d1d4179
Autor:
Yiming Wang, Ruben Garrido-Oter, Jingni Wu, Thomas M. Winkelmüller, Matthew Agler, Thomas Colby, Tatsuya Nobori, Eric Kemen, Kenichi Tsuda
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
During innate immune responses, plant cells secrete proteases into apoplastic spaces where they contribute to pathogen resistance. Here Wang et al. show that the Arabidopsis SAP1 and SAP2 proteases cleave the bacterial MucD protein to inhibit growth
Externí odkaz:
https://doaj.org/article/550b7d3412424bf1a7f98c3e009be790
Autor:
Jan Schulze Hüynck, Farnusch Kaschani, Karina van der Linde, Sebastian Ziemann, André N. Müller, Thomas Colby, Markus Kaiser, Johana C. Misas Villamil, Gunther Doehlemann
Publikováno v:
Frontiers in Plant Science, Vol 10 (2019)
Plant proteases are key regulators of plant cell processes such as seed development, immune responses, senescence and programmed cell death (PCD). Apoplastic papain-like cysteine proteases (PL) are hubs in plant-microbe interactions and play an impor
Externí odkaz:
https://doaj.org/article/69a68c306c0946c69b0d3676cfd1ec8b
Publikováno v:
Respiratory Medicine Case Reports, Vol 27, Iss , Pp - (2019)
Benign metastasizing leiomyoma (BML) is a rare benign smooth muscle neoplasm that originates in the uterus and metastasizes to distant sites—most commonly the lungs. BMLs are often found incidentally in patients with a history of uterine leiomyoma(
Externí odkaz:
https://doaj.org/article/511e53bb0aa04fceba637d3b654673f8
Autor:
Edward Bartlett, Juan José Bonfiglio, Evgeniia Prokhorova, Thomas Colby, Florian Zobel, Ivan Ahel, Ivan Matic
Publikováno v:
Cell Reports, Vol 24, Iss 13, Pp 3488-3502.e5 (2018)
Summary: Serine ADP-ribosylation (Ser-ADPr) is a recently discovered protein modification that is catalyzed by PARP1 and PARP2 when in complex with the eponymous histone PARylation factor 1 (HPF1). In addition to numerous other targets, core histone
Externí odkaz:
https://doaj.org/article/f0809864647342958677be9548b2a375
Autor:
Alisa Zhiteneva, Juan Jose Bonfiglio, Alexandr Makarov, Thomas Colby, Paola Vagnarelli, Eric C. Schirmer, Ivan Matic, William C. Earnshaw
Publikováno v:
Open Biology, Vol 7, Iss 9 (2017)
How eukaryotic chromosomes are compacted during mitosis has been a leading question in cell biology since the nineteenth century. Non-histone proteins such as condensin complexes contribute to chromosome shaping, but appear not to be necessary for mi
Externí odkaz:
https://doaj.org/article/ec56b7ce31d64db289ebf27f0d06f770
Autor:
Cristiano Claudino Oliveira, Marcelo Padovani Toledo de Moraes, Thomas Colby, Gilmar Felisberto Oliveira, Erica Nishida Hasimoto, Daniele Cristina Cataneo, Antônio José Maria Cataneo, Julio De Faveri
Publikováno v:
Autopsy and Case Reports, Vol 6, Iss 4 (2016)
Solitary fibrous tumor (SFT) is a mesenchymal neoplasm that appears primarily in the pleura and rarely in intrapulmonary or endobronchial topography. The authors report the case of a 47-year-old woman who presented obstructive respiratory symptoms fo
Externí odkaz:
https://doaj.org/article/c4f9186f60ec4af2b5e4db73545c8b75
Autor:
Edoardo José Longarini, Helen Dauben, Carolina Locatelli, Anne R. Wondisford, Rebecca Smith, Charlotte Muench, Andreas Kolvenbach, Michelle Lee Lynskey, Alexis Pope, Juan José Bonfiglio, Eva Pinto Jurado, Roberta Fajka-Boja, Thomas Colby, Marion Schuller, Ivan Ahel, Gyula Timinszky, Roderick J. O’Sullivan, Sébastien Huet, Ivan Matic
Publikováno v:
Molecular Cell
Molecular Cell, 2023, 83 (10), pp.1743-1760.e11. ⟨10.1016/j.molcel.2023.03.027⟩
Molecular Cell, 2023, 83 (10), pp.1743-1760.e11. ⟨10.1016/j.molcel.2023.03.027⟩
International audience; PARP1, an established anti-cancer target that regulates many cellular pathways, including DNA repair signaling, has been intensely studied for decades as a poly(ADP-ribosyl)transferase. Although recent studies have revealed th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1601d4dc993fd64a43906626e289a5e
https://hal.science/hal-04121387/file/hal-04121387.pdf
https://hal.science/hal-04121387/file/hal-04121387.pdf
Autor:
Momen M. Wahidi, Angela Christine Argento, Kamran Mahmood, Scott L. Shofer, Coral Giovacchini, Aaron Pulsipher, Matthew Hartwig, Betty Tong, John M. Carney, Thomas Colby, Ben Neely, Xiaofei Wang, Jane Dematte, Neil Ninan, Sonye Danoff, Lake Daniel Morrison, Lonny Yarmus
Publikováno v:
Kompass Neumología. 4:171-176
Justificación: La criobiopsia pulmonar transbronquial (TBLC) se ha propuesto como un método menos invasivo para obtener un diagnóstico tisular en pacientes con enfermedad pulmonar intersticial (EPI). El rendimiento diagnóstico de la TBLC en compa
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nat Commun
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nat Commun
Legionella pneumophila (LP) avoids phagocytosis by secreting nearly 300 effector proteins into the host cytosol. SidE family of effectors (SdeA, SdeB, SdeC and SidE) employ phosphoribosyl ubiquitination to target multiple host Rab GTPases and innate