Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Thomas Cokelaer"'
Autor:
Laxmi Shanker Rai, Murielle Chauvel, Hiram Sanchez, Lasse van Wijlick, Corinne Maufrais, Thomas Cokelaer, Natacha Sertour, Mélanie Legrand, Kaustuv Sanyal, David R Andes, Sophie Bachellier-Bassi, Christophe d'Enfert
Publikováno v:
PLoS Biology, Vol 22, Iss 6, p e3002693 (2024)
Candida albicans is a commensal of the human microbiota that can form biofilms on implanted medical devices. These biofilms are tolerant to antifungals and to the host immune system. To identify novel genes modulating C. albicans biofilm formation, w
Externí odkaz:
https://doaj.org/article/950f30e96bf34aa18748985f1e9630d6
Autor:
Camille Sous, Wafa Frigui, Alexandre Pawlik, Fadel Sayes, Laurence Ma, Thomas Cokelaer, Roland Brosch
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 6 (2024)
ABSTRACT Four species of non-tuberculous mycobacteria (NTM) rated as biosafety level 1 or 2 (BSL-1/BSL-2) organisms and showing higher genomic similarity with Mycobacterium tuberculosis (Mtb) than previous comparator species Mycobacterium kansasii an
Externí odkaz:
https://doaj.org/article/ba98bcfd71dc497e9da14c0fddcb9a9d
Autor:
Cecilia Patitucci, Juan Diego Hernández-Camacho, Elodie Vimont, Sonny Yde, Thomas Cokelaer, Thibault Chaze, Quentin Giai Gianetto, Mariette Matondo, Anastasia Gazi, Ivan Nemazanyy, David A. Stroud, Daniella H. Hock, Erminia Donnarumma, Timothy Wai
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Hepatic steatosis is the result of imbalanced nutrient delivery and metabolism in the liver and is the first hallmark of Metabolic dysfunction-associated steatotic liver disease (MASLD). MASLD is the most common chronic liver disease and inv
Externí odkaz:
https://doaj.org/article/b09b45d1602f49a8a762f6a77dc40a33
Autor:
Anne-Aurélie Lopes, Sol Vendrell-Fernández, Julien Deschamps, Sonia Georgeault, Thomas Cokelaer, Romain Briandet, Jean-Marc Ghigo
Publikováno v:
mBio, Vol 15, Iss 5 (2024)
ABSTRACTBacteroides thetaiotaomicron is a prominent member of the human gut microbiota contributing to nutrient exchange, gut function, and maturation of the host’s immune system. This obligate anaerobe symbiont can adopt a biofilm lifestyle, and i
Externí odkaz:
https://doaj.org/article/a1c5e22701f341c6b062da72aadb1c88
Autor:
Egill Richard, Baptiste Darracq, Eloi Littner, Gael A Millot, Valentin Conte, Thomas Cokelaer, Jan Engelstädter, Eduardo P C Rocha, Didier Mazel, Céline Loot
Publikováno v:
PLoS Genetics, Vol 20, Iss 4, p e1011231 (2024)
Integrons are adaptive devices that capture, stockpile, shuffle and express gene cassettes thereby sampling combinatorial phenotypic diversity. Some integrons called sedentary chromosomal integrons (SCIs) can be massive structures containing hundreds
Externí odkaz:
https://doaj.org/article/7858995495e6436592d51e1f865adab5
Autor:
Linda Grillova, Thomas Cokelaer, Jean-François Mariet, Juliana Pipoli da Fonseca, Mathieu Picardeau
Publikováno v:
BMC Infectious Diseases, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background The life-threatening pathogen Leptospira interrogans is the most common agent of leptospirosis, an emerging zoonotic disease. However, little is known about the strains that are currently circulating worldwide due to the fastidiou
Externí odkaz:
https://doaj.org/article/0fa8ffebbf8b419ea4a4d4aeee9d8542
Autor:
Juliana Pipoli da Fonseca, Etienne Kornobis, Elodie Turc, Vincent Enouf, Laure Lemée, Thomas Cokelaer, Marc Monot
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Since the beginning of the SARS-CoV-2 coronavirus pandemic, genome sequencing is essential to monitor viral mutations over time and by territory. This need for complete genetic information is further reinforced by the rapid spread of variant
Externí odkaz:
https://doaj.org/article/d938ec81c7c3412fbd515b4038fdc70c
Autor:
Estelle Vincendeau, Wenming Wei, Xuefei Zhang, Cyril Planchais, Wei Yu, Hélène Lenden-Hasse, Thomas Cokelaer, Juliana Pipoli da Fonseca, Hugo Mouquet, David J. Adams, Frederick W. Alt, Stephen P. Jackson, Gabriel Balmus, Chloé Lescale, Ludovic Deriano
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
SHLD1, as a component of the Shieldin (SHLD) complex, mediates DNA repair via non-homologous end-joining (NHEJ), an essential process during lymphocyte development. Here the authors show that SHLD1 is actually dispensable for lymphocyte development a
Externí odkaz:
https://doaj.org/article/29536601a7d546f9b2f28d98202fe331
Autor:
Mathieu Claireaux, Rémy Robinot, Jérôme Kervevan, Mandar Patgaonkar, Isabelle Staropoli, Anne Brelot, Alexandre Nouël, Stacy Gellenoncourt, Xian Tang, Mélanie Héry, Stevenn Volant, Emeline Perthame, Véronique Avettand-Fenoël, Julian Buchrieser, Thomas Cokelaer, Christiane Bouchier, Laurence Ma, Faroudy Boufassa, Samia Hendou, Valentina Libri, Milena Hasan, David Zucman, Pierre de Truchis, Olivier Schwartz, Olivier Lambotte, Lisa A. Chakrabarti
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Here, Claireaux et al. show that people who naturally control HIV infection express lower levels of the viral co-receptor CCR5 in specific CD4+ T cells, and that this results from mutations or receptor internalization by CD4+ T cell-produced chemokin
Externí odkaz:
https://doaj.org/article/e28895a87b7e41c89703ad60c628fffd
Autor:
Laura Piel, K Shanmugha Rajan, Giovanni Bussotti, Hugo Varet, Rachel Legendre, Caroline Proux, Thibaut Douché, Quentin Giai-Gianetto, Thibault Chaze, Thomas Cokelaer, Barbora Vojtkova, Nadav Gordon-Bar, Tirza Doniger, Smadar Cohen-Chalamish, Praveenkumar Rengaraj, Céline Besse, Anne Boland, Jovana Sadlova, Jean-François Deleuze, Mariette Matondo, Ron Unger, Petr Volf, Shulamit Michaeli, Pascale Pescher, Gerald F Späth
Publikováno v:
PLoS Pathogens, Vol 18, Iss 3, p e1010375 (2022)
The protozoan parasite Leishmania donovani causes fatal human visceral leishmaniasis in absence of treatment. Genome instability has been recognized as a driver in Leishmania fitness gain in response to environmental change or chemotherapy. How genom
Externí odkaz:
https://doaj.org/article/6054875378b740aabcc0a4e834d05c3b