Zobrazeno 1 - 10
of 345
pro vyhledávání: '"Thomas Chang"'
Publikováno v:
BMC Medical Education, Vol 20, Iss 1, Pp 1-12 (2020)
Abstract Background Taiwan’s colleges and universities are struggling to maintain their student enrollment rates owing to the declining fertility rate. Focusing on students in higher education programs, this study aims to analyze online behavioral
Externí odkaz:
https://doaj.org/article/d22345f63bfa4f88af49ecee43b407d6
Autor:
Peter Kirk, Murali Addepalli, Thomas Chang, Palakshi Obalapur, Peiwen Kuo, Phi Quach, Jonathan Zalevsky, Rhoneil Pena, Saul Kivimae, Werner Rubas, Takahiro Miyazaki, Loui Madakamutil, Mekhala Maiti, Marlene Hennessy, Sara Sheibani, Joanna Wilczek, Janet Cetz, Andrew Moffett, Yinyan Tang, Jicai Huang, Dawei Sheng
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 5 (2021)
Background NKTR-255 is a novel polyethylene glycol-conjugate of recombinant human interleukin-15 (rhIL-15), which was designed to retain all known receptor binding interactions of the IL-15 molecule. We explored the biologic and pharmacologic differe
Externí odkaz:
https://doaj.org/article/e08faa8782fa46a5a98602da0126f298
In situ structures of rotavirus polymerase in action and mechanism of mRNA transcription and release
Autor:
Ke Ding, Cristina C. Celma, Xing Zhang, Thomas Chang, Wesley Shen, Ivo Atanasov, Polly Roy, Z. Hong Zhou
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Rotaviruses are of great medical significance because they cause gastroenteritis in children. Here the authors provide insights into the mechanism of viral mRNA transcription by determining the in situ cryo-EM structures of a working rotavirus’ RNA
Externí odkaz:
https://doaj.org/article/d7ab0cfbd1d642369d08a8a85f7cd652
Autor:
Neha Dixit, Christie Fanton, John L. Langowski, Yolanda Kirksey, Peter Kirk, Thomas Chang, Janet Cetz, Vidula Dixit, Grace Kim, Peiwen Kuo, Mekhala Maiti, Yinyan Tang, Laurie A. VanderVeen, Ping Zhang, Myong Lee, Jerome Ritz, Yusuke Kamihara, Chunmei Ji, Werner Rubas, Theresa D. Sweeney, Stephen K. Doberstein, Jonathan Zalevsky
Publikováno v:
Journal of Translational Autoimmunity, Vol 4, Iss , Pp 100103- (2021)
Impaired interleukin-2 (IL-2) production and regulatory T-cell dysfunction have been implicated as immunological mechanisms central to the pathogenesis of multiple autoimmune and inflammatory diseases. NKTR-358, a novel regulatory T-cell stimulator,
Externí odkaz:
https://doaj.org/article/63812ff90adf4c7e9449ec1fa8aa92e5
Autor:
Chen-Feng Chiu, Ru-Huei Fu, Shan-hui Hsu, Yang-Hao (Alex) Yu, Shun-Fa Yang, Thomas Chang-Yao Tsao, Kai-Bo Chang, Chun-An Yeh, Cheng-Ming Tang, Sheng-Chu Huang, Huey-Shan Hung
Publikováno v:
Cancers, Vol 13, Iss 21, p 5317 (2021)
Gold nanoparticles (AuNPs) were fabricated with biocompatible collagen (Col) and then conjugated with berberine (BB), denoted as Au-Col-BB, to investigate the endocytic mechanisms in Her-2 breast cancer cell line and in bovine aortic endothelial cell
Externí odkaz:
https://doaj.org/article/d44c17088d28454ba2a0cf5c8d030b07
Autor:
Kai-Ling Lee, Tsung-Ching Lai, Yao-Chen Wang, Pei-Chun Shih, Yi-Chieh Yang, Thomas Chang-Yao Tsao, Tu-Chen Liu, Yu-Ching Wen, Lun-Ching Chang, Shun-Fa Yang, Ming-Hsien Chien
Publikováno v:
Genes, Vol 12, Iss 3, p 427 (2021)
Non-small cell lung cancer (NSCLC) is a typical inflammation-associated cancer, and lung adenocarcinoma (LUAD) is the most common histopathological subtype. Epidermal growth factor receptor (EGFR) mutations are the most common driver mutations of LUA
Externí odkaz:
https://doaj.org/article/7134408d96194196ad9917690657b284
Autor:
Jer-Hwa Chang, Tsung-Ching Lai, Po-Jen Yang, Pei-Chun Shih, Yi-Chieh Yang, Kai-Ling Lee, Tu-Chen Liu, Thomas Chang-Yao Tsao, Shun-Fa Yang, Ming-Hsien Chien
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 21, p 8023 (2020)
Lung adenocarcinoma (LADC) is a major subtype of lung cancer, particularly among populations of East Asia. The epidermal growth factor receptor (EGFR) is the most frequently mutated oncogene promoting LADC progression and can serve as a therapeutic t
Externí odkaz:
https://doaj.org/article/32336bd5ee9c4ef9bd0d841c056fc219
Autor:
Ching-Hsiung Lin, Po-Jen Yang, Sheng-Hao Lin, Kun-Tu Yeh, Thomas Chang-Yao Tsao, Yu-En Chen, Shu-Hui Lin, Shun-Fa Yang
Publikováno v:
Diagnostics, Vol 10, Iss 9, p 692 (2020)
EGFR mutation status is considered as an important predictor of therapeutic responsiveness in non-small-cell lung carcinoma patients. Recent evidence suggests that antioxidant gene polymorphisms are potential predictors of lung cancer risk. Thus, str
Externí odkaz:
https://doaj.org/article/6a8b4672fc91497aa977fb77137d2c18
Autor:
Jui-Wen Ma, Thomas Chang-Yao Tsao, Yi-Ting Hsi, Ying-Chao Lin, Yuhsin Chen, Yeh Chen, Chi-Tang Ho, Jung-Yie Kao, Tzong-Der Way
Publikováno v:
Journal of Functional Foods, Vol 22, Iss , Pp 101-112 (2016)
Non-small-cell lung cancer (NSCLC) accounts for approximately 85% of all lung cancers, and has highly metastatic capacity and poor prognosis. The anti-tumour activity and the corresponding signal pathways of spring Curcuma aromatica Salisb essential
Externí odkaz:
https://doaj.org/article/ae6a33cfd97c486491b719b40e5a610b
Autor:
Ya-Yen Yu, Hui-Ling Chiou, Shih-Ming Tsao, Chen-Cheng Huang, Chih-Yun Lin, Chia-Yi Lee, Thomas Chang-Yao Tsao, Shun-Fa Yang, Yi-Wen Huang
Publikováno v:
Diagnostics, Vol 10, Iss 5, p 266 (2020)
Carbonic anhydrase 9 (CA9) plays a vital role in lung cancer progression. The current study explored the effect of CA9 gene polymorphisms and the epidermal growth factor receptor (EGFR) mutations on the clinicopathological characters of lung adenocar
Externí odkaz:
https://doaj.org/article/a860982f0818486caa8505601e9ed227