Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Thomas C. Watson"'
Publikováno v:
Frontiers in Systems Neuroscience, Vol 17 (2023)
Cerebellar networks have traditionally been linked to sensorimotor control. However, a large body of evidence suggests that cerebellar functions extend to non-motor realms, such as fear-based emotional processing and that these functions are supporte
Externí odkaz:
https://doaj.org/article/fc3dc02dc44d4dc4b108e9cd2f4d1769
Autor:
Natasha J. Anstey, Vijayakumar Kapgal, Shashank Tiwari, Thomas C. Watson, Anna K. H. Toft, Owen R. Dando, Felicity H. Inkpen, Paul S. Baxter, Zrinko Kozić, Adam D. Jackson, Xin He, Mohammad Sarfaraz Nawaz, Aiman Kayenaat, Aditi Bhattacharya, David J. A. Wyllie, Sumantra Chattarji, Emma R. Wood, Oliver Hardt, Peter C. Kind
Publikováno v:
Molecular Autism, Vol 13, Iss 1, Pp 1-19 (2022)
Abstract Background Mutations in the postsynaptic transmembrane protein neuroligin-3 are highly correlative with autism spectrum disorders (ASDs) and intellectual disabilities (IDs). Fear learning is well studied in models of these disorders, however
Externí odkaz:
https://doaj.org/article/3d9e90cbc8e047a6a47ce223c07a8fd8
Autor:
Natasha J. Anstey, Vijayakumar Kapgal, Shashank Tiwari, Thomas C. Watson, Anna K. H. Toft, Owen R. Dando, Felicity H. Inkpen, Paul S. Baxter, Zrinko Kozić, Adam D. Jackson, Xin He, Mohammad Sarfaraz Nawaz, Aiman Kayenaat, Aditi Bhattacharya, David J. A. Wyllie, Sumantra Chattarji, Emma R. Wood, Oliver Hardt, Peter C. Kind
Publikováno v:
Anstey, N J, Kapgal, V, Tiwari, S, Watson, T C, Toft, A K H, Dando, O R, Inkpen, F H, Baxter, P S, Kozic, Z, Jackson, A D, He, X, Nawaz, M S, Kayenaat, A, Bhattacharya, A, Wyllie, D J A, Chattarji, S, Wood, E R, Hardt, O & Kind, P C 2022, ' Imbalance of flight-freeze responses and their cellular correlates in the Nlgn3-/y rat model of autism ', Molecular Autism, vol. 13, 34 . https://doi.org/10.1186/s13229-022-00511-8
BackgroundMutations in the postsynaptic transmembrane protein neuroligin-3 are highly correlative with autism spectrum disorders (ASDs) and intellectual disabilities (IDs). Fear learning is well studied in models of these disorders, however differenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02c236db287e28b698524b9c96f2a988
https://doi.org/10.1186/s13229-022-00511-8
https://doi.org/10.1186/s13229-022-00511-8
Autor:
Thomas C Watson, Katerina Hristova, Alfredo Gonzalez-Sulser, Cristina Martinez-Gonzalez, Kevan Hashemi, Neela K. Codadu, Matthew F. Nolan, Peter C. Kind
Publikováno v:
Brain
Hristova, K, Martinez Gonzalez, C, Watson, T, Codadu, N, Hashemi, K, Kind, P, Nolan, M & Gonzalez-Sulser, A 2021, ' Medial Septal GABAergic Neurons Reduce Seizure Duration Upon Optogenetic Closed-Loop Stimulation ', Brain, vol. 144, no. 5, pp. 1576–1589 . https://doi.org/10.1093/brain/awab042
Hristova, K, Martinez Gonzalez, C, Watson, T, Codadu, N, Hashemi, K, Kind, P, Nolan, M & Gonzalez-Sulser, A 2021, ' Medial Septal GABAergic Neurons Reduce Seizure Duration Upon Optogenetic Closed-Loop Stimulation ', Brain, vol. 144, no. 5, pp. 1576–1589 . https://doi.org/10.1093/brain/awab042
Seizures can emerge from multiple or large foci in temporal lobe epilepsy, complicating focally targeted strategies such as surgical resection or the modulation of the activity of specific hippocampal neuronal populations through genetic or optogenet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3519087d6305deed7ad76b00b2b8e37a
http://europepmc.org/articles/PMC8219369
http://europepmc.org/articles/PMC8219369
Autor:
Jaime Olavarrieta, Stephen Meek, Angela Salzano, Tamir Chandra, Jun Wei, Linda Sutherland, Thomas C Watson, Taeho Oh, Anagha Joshi, Tom Burdon, Daniel F. Carlson
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Vol 14, Iss 1, Pp 154-166 (2020)
Meek, S, Wei, J, Oh, T, Olavarrieta, J, Sutherland, L, Carlson, D F, Salzano, A, Chandra, T, Joshi, A & Burdon, T 2020, ' A stem cell reporter for investigating pluripotency and self-renewal in the rat. ', Stem Cell Reports . https://doi.org/10.1016/j.stemcr.2019.12.001
Stem Cell Reports, Vol 14, Iss 1, Pp 154-166 (2020)
Meek, S, Wei, J, Oh, T, Olavarrieta, J, Sutherland, L, Carlson, D F, Salzano, A, Chandra, T, Joshi, A & Burdon, T 2020, ' A stem cell reporter for investigating pluripotency and self-renewal in the rat. ', Stem Cell Reports . https://doi.org/10.1016/j.stemcr.2019.12.001
Summary Rat embryonic stem cells (rESCs) are capable of contributing to all differentiated tissues, including the germ line in chimeric animals, and represent a unique, authentic alternative to mouse embryonic stem cells for studying stem cell plurip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55334f9a88e35d5468f1fe725aab9f2a
https://doi.org/10.1016/j.stemcr.2019.12.001
https://doi.org/10.1016/j.stemcr.2019.12.001
Autor:
Thomas C. Watson, Richard Apps
Publikováno v:
Handbook of the Cerebellum and Cerebellar Disorders ISBN: 9783319979113
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf4a1c27ff7e535bef25171d37ca7dc4
https://doi.org/10.1007/978-3-030-23810-0_48
https://doi.org/10.1007/978-3-030-23810-0_48
Autor:
Natasha J, Anstey, Vijayakumar, Kapgal, Shashank, Tiwari, Thomas C, Watson, Anna K H, Toft, Owen R, Dando, Felicity H, Inkpen, Paul S, Baxter, Zrinko, Kozić, Adam D, Jackson, Xin, He, Mohammad Sarfaraz, Nawaz, Aiman, Kayenaat, Aditi, Bhattacharya, David J A, Wyllie, Sumantra, Chattarji, Emma R, Wood, Oliver, Hardt, Peter C, Kind
Publikováno v:
Molecular autism. 13(1)
Mutations in the postsynaptic transmembrane protein neuroligin-3 are highly correlative with autism spectrum disorders (ASDs) and intellectual disabilities (IDs). Fear learning is well studied in models of these disorders, however differences in fear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2eba4b5c5f50b8abb5c2bf2ef1b0ffb6
https://pubmed.ncbi.nlm.nih.gov/35850732
https://pubmed.ncbi.nlm.nih.gov/35850732
Stem cell-derived macrophages as a new platform for studying host-pathogen interactions in livestock
Autor:
Pablo J. Ross, Jayne Hope, Monika Nowak-Imialek, Alan Archibald, Gus R. McFarlane, Heiner Niemann, Christine Tait-Burkard, Linda Sutherland, Sarah Brown, Thomas C Watson, Alistair Lawrence, Pentao Liu, Barry W. McColl, Felicity J. Wynne, Stephen McCleary, Musa A. Hassan, Tom Burdon, Emily Charlton, Finn Grey, Chloe Criag, Anton Gossner, Cosmin Chintoan-Uta, Lucas Lefevre, Xuefei Gao, Stephen Meek, Ryan Taylor, Sarah Fletcher, Tim Regan, Falko Steinbach, Helen Crooke, Laura E.M. Dunn, Barbara Shih, Mark P. Stevens, Lel Eory, Gerard Thomson, Pip Beard
Infectious diseases of farmed and wild animals pose a recurrent threat to food security and human health. The macrophage, a key component of the innate immune system, is the first line of defence against many infectious agents and plays a major role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9201f265bd6809a46722e23d9370c94
https://doi.org/10.1101/2021.09.10.459580
https://doi.org/10.1101/2021.09.10.459580
Autor:
Thomas C Watson
Publikováno v:
Frontiers in Systems Neuroscience, Vol 9 (2015)
Externí odkaz:
https://doaj.org/article/7dc00acebc374ea09ec4eebc6b03a9b5
Publikováno v:
Frontiers in Systems Neuroscience, Vol 8 (2014)
Although recent neuroanatomical evidence has demonstrated closed-loop connectivity between prefrontal cortex and the cerebellum, the physiology of cerebello-cerebral circuits and the extent to which cerebellar output modulates neuronal activity in ne
Externí odkaz:
https://doaj.org/article/064207e1bd4a4233918a93feee516994