Výsledky vyhledávání - "Thomas C. VanderHeyden"

Central Hypothyroidism Reveals Compound Heterozygous Mutations in the Pit-1 Gene

Autor: John S. Parks, Barry H. Rich, David L. Hurley, Matthew E. Adess, Thomas C. VanderHeyden, Milton R. Brown, Ty C. Voss, Ira M. Rosenthal

Publikováno v: Hormone Research in Paediatrics. 49:98-102

Mutations in the gene encoding the Pit-1 transcriptional activator interfere with the embryologic determination and ultimate functions of anterior pituitary cells that produce growth hormone (GH), prolactin (Prl) and thyroid-stimulating hormone (TSH)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8463ad89cb953c03bc00e6625d04d48d
https://doi.org/10.1159/000023134

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Mouse growth hormone transcription factor Zn-16: unique bipartite structure containing tandemly repeated zinc finger domains not reported in rat Zn-15

Autor: Carol J. Phelps, David L. Hurley, Thomas C. VanderHeyden, Kevin M Ahlers, Ty C Voss, Patrick W. Wojtkiewicz, Zachary Harrelson, Teresa M. Mangin

Publikováno v: Molecular and cellular endocrinology. 159(1-2)

Rat Zn-15 is a transcription factor activating GH gene expression by synergistic interactions with Pit-1, named for 15 DNA-binding zinc fingers, including fingers IX, X, and XI that are responsible for GH promoter binding. In this study, a mouse cDNA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b2c716b8d26c24107e8d448cc3751fb
https://pubmed.ncbi.nlm.nih.gov/10687855

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