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pro vyhledávání: '"Thomas C. Mayer"'
Autor:
Thomas C. Mayer
Publikováno v:
Journal of Experimental Zoology. 210:81-87
Through the use of dermal-epidermal recombination methods a competition between mouse embryo melanoblasts of the genotype Wv/w C/C, w/w c/c, Sld/sl C/C and sl/sl c/c was established. Control combinations were made between C/C and c/d components. The
Publikováno v:
Development. 32:707-713
The site of action of the mutation fuzzy (fz) was investigated by the method of dermal- epidermal recombination. Skins from 14-day mutant and normal mouse embryos were sepa- rated into dermal and epidermal components, recombined, and grown in the mou
Autor:
Thomas C. Mayer
Publikováno v:
Developmental Biology. 94:509-514
Isolated pigment cells in long-term cultures derived from 14-day mouse epidermal ectoderm are responsive to cAMP in the culture medium. By 48 hr after stimulation 62% of the cells are proliferating as measured by the uptake of [3H]thymidine, compared
Autor:
Thomas C. Mayer, M L Lamoreux
Publikováno v:
Developmental Biology. 46:160-166
The site of gene action of the extension ( e ) locus in the mouse was investigated through the use of the neural tube-skin recombination grafting technique. Recessive yellow ( e e , a a ) neural tubes were grown with nonyellow ( E + E + , a a ) skin,
Autor:
Thomas C. Mayer
Publikováno v:
Developmental Biology. 11:319-334
The site of action of piebald, a major spotting gene in the mouse, was investigated according to a method by which embryonic neural tube and skin of various genotypes were grafted in combination to White Leghorn chick embryo hosts. Melanoblasts from
Autor:
Thomas C. Mayer
Publikováno v:
Developmental Biology. 15:521-535
White-spotting patterns in mice have been attributed alternatively to a selective migration of melanoblasts into certain regions of the skin, or to a failure of the melanoblasts to differentiate in the areas that remain pigment free. These two altern
Autor:
Thomas C. Mayer, Jill L. Fishbane
Publikováno v:
Genetics. 71:297-303
Alleles at the agouti locus in the mouse determine the synthesis of either phaeomelanin or eumelanin by follicular melanocytes by altering the hair follicle environment. The method of dermal-epidermal recombination of mouse skin from C57BL/6J a/a and
Autor:
Thomas C. Mayer
Publikováno v:
Journal of Experimental Zoology. 184:345-352
Mice homozygous for the gene steel (S1) are black-eyed white, anemic and sterile. Previous studies have shown that the pigment defect in the skin and hair results from a failure of the tissue environment to support pigment cell development. In an att
Autor:
Leroy Oddis, Thomas C. Mayer
Publikováno v:
The Journal of experimental zoology. 202(3)
Pigment cell differentiation was studied in cell cultures derived from 14-day embryonic mouse skin, and in cultures of dermal or epidermal skin cells. Cell cultures from dissociated whole skin produced melanocytes in very small numbers, and they were
Autor:
Thomas C. Mayer
Publikováno v:
Developmental biology. 79(2)
Cultures of 14-day embryonic mouse epidermis that include melanoblasts initiate melanin synthesis 30 hr after plating, a schedule that is 2.5 days earlier than in vivo. In order to determine if the accelerated differentiation of melanoblasts is relat