Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Thomas C. Cunnane"'
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e29209 (2011)
Prejunctional nicotinic acetylcholine receptors (nAChRs) amplify postganglionic sympathetic neurotransmission, and there are indications that intraterminal Ca(2+) stores might be involved. However, the mechanisms by which nAChR activation stimulates
Externí odkaz:
https://doaj.org/article/46d7d6dc1de3470eb4731e1c96daeee2
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 464:493-502
Patch-clamp experiments were performed to investigate the molecular properties of resurgent-like currents in single smooth muscle cells dispersed from mouse vas deferens, utilizing both Na(V)1.6-null mice (Na(V)1.6(-/-)), lacking the expression of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66adcf2df4e7f76b4b8276373878ef8d
https://doi.org/10.1007/s00424-012-1153-4
https://doi.org/10.1007/s00424-012-1153-4
Autor:
Masatoshi Nomura, Hai Lei Zhu, Richard D. Wassall, Noriyoshi Teramoto, Maki Takai, Thomas C. Cunnane, Hidetaka Morinaga
Publikováno v:
British Journal of Pharmacology. 157:1483-1493
Background and purpose: The effects of veratridine, an alkaloid found in Liliaceae plants, on tetrodotoxin (TTX)-sensitive voltage-gated Na+ channels were investigated in mouse vas deferens. Experimental approach: Effects of veratridine on TTX-sensit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf355f37f2cf845b4b95d788bb3c84ba
https://doi.org/10.1111/j.1476-5381.2009.00301.x
https://doi.org/10.1111/j.1476-5381.2009.00301.x
Publikováno v:
British Journal of Pharmacology. 150:906-912
Background and purpose: Nicotinic agonists increase sympathetic field-stimulus-evoked contraction of the rodent vas deferens, presumably by increasing evoked neurotransmitter release. This presumption was tested in two species. Experimental approach:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8f032be9246a30a56aa535127d15d29
https://doi.org/10.1038/sj.bjp.0707183
https://doi.org/10.1038/sj.bjp.0707183
Publikováno v:
The Journal of Physiology. 553:627-635
The detection of focal Ca(2+) transients (called neuroeffector Ca(2+) transients, or NCTs) in smooth muscle of the mouse isolated vas deferens has been used to detect the packeted release of ATP from nerve terminal varicosities acting at postjunction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecc047f5e6abb875fde8ce0d4239dcab
https://doi.org/10.1113/jphysiol.2003.049734
https://doi.org/10.1113/jphysiol.2003.049734
Publikováno v:
The Journal of Physiology. 541:849-862
A confocal Ca2+ imaging technique has been used to detect ATP release from individual sympathetic varicosities on the same nerve terminal branch. Varicose nerve terminals and smooth muscle cells in mouse vas deferens were loaded with the Ca2+ indicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::439a8bee06bc5477954489bbd7f5dcb8
https://doi.org/10.1113/jphysiol.2002.019612
https://doi.org/10.1113/jphysiol.2002.019612
Publikováno v:
British Journal of Pharmacology. 135:197-205
The effects of endothelin-1 (ET-1) on guinea-pig lower oesophageal sphincter (LOS) circular smooth muscle were investigated by using intracellular microelectrodes and isometric tension recording techniques. ET-1 produced biphasic mechanical responses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1703217a612914e3808bf3d657016e3
https://doi.org/10.1038/sj.bjp.0704426
https://doi.org/10.1038/sj.bjp.0704426
Publikováno v:
Neuroscience. 106:395-403
While nicotine is known to act at neuronal nicotinic acetylcholine receptors (nAChRs) to facilitate neurotransmitter release, the mechanisms underlying this action are poorly understood. Some of its effects are known to be mediated by presynaptic rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ab011d82cbc2db581335208cbc758c3
https://doi.org/10.1016/s0306-4522(01)00280-9
https://doi.org/10.1016/s0306-4522(01)00280-9
Autor:
Thomas C. Cunnane, James A. Brock
Publikováno v:
British Journal of Pharmacology. 126:11-18
The effects of Ca2+ concentration and Ca2+ channel blockers on noradrenaline (NA) and adenosine 5′-triphosphate (ATP) release from postganglionic sympathetic nerves have been investigated in rat tail arteries in vitro. Intracellularly recorded exci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04d914c9e7507d045b2de48a1cdcb4f4
https://doi.org/10.1038/sj.bjp.0702256
https://doi.org/10.1038/sj.bjp.0702256
Publikováno v:
British Journal of Pharmacology. 120:769-776
The effects of prejunctional β-adrenoceptor activation on electrically evoked noradrenaline (NA) and adenosine 5′-triphosphate (ATP) were studied by use of continuous amperometry and conventional intracellular recording techniques. Excitatory junc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::beff1e9393d1045f9bc727a9687cec98
https://doi.org/10.1038/sj.bjp.0700959
https://doi.org/10.1038/sj.bjp.0700959