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pro vyhledávání: '"Thomas C. Brunold"'
Autor:
Thomas C. Brunold
Publikováno v:
CHIMIA, Vol 58, Iss 4 (2004)
This article illustrates how the combined computational/spectroscopic methodology used in our studies of metal centers in proteins and cofactors can be applied to vitamin B12 and its biologically relevant derivatives. The B12 cofactors have long fasc
Externí odkaz:
https://doaj.org/article/28b6fbadf6b94302ace68705ef14621b
Publikováno v:
Accounts of Chemical Research. 55:2480-2490
ConspectusIn recent years, considerable progress has been made toward elucidating the geometric and electronic structures of thiol dioxygenases (TDOs). TDOs catalyze the conversion of substrates with a sulfhydryl group to their sulfinic acid derivati
Publikováno v:
Biochemistry
Queuosine (Q) is a highly modified nucleoside of transfer RNA that is formed from guanosine triphosphate over the course of eight steps. The final step in this process, involving the conversion of epoxyqueuosine (oQ) to Q, is catalyzed by the enzyme
Autor:
Joshua R. Miller, Thomas C. Brunold
Publikováno v:
Methods in Enzymology ISBN: 9780443185922
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9567a59b8cb1989611db72c0be6be762
https://doi.org/10.1016/bs.mie.2023.01.002
https://doi.org/10.1016/bs.mie.2023.01.002
Autor:
Laura D, Elmendorf, Thomas C, Brunold
Publikováno v:
Methods in enzymology. 669
Electronic absorption (Abs) and circular dichroism (CD) spectroscopic techniques have been used successfully for over half a century in studies of free and enzyme-bound B
Autor:
Thomas C. Brunold, Albert Kallon, Kurt Warncke, Zhu Li, Elizabeth D. Greenhalgh, Markus Ruetz, Umar T. Twahir, Ruma Banerjee
Publikováno v:
Inorganic Chemistry. 59:16065-16072
CblC is a chaperone that catalyzes removal of the β-axial ligand of cobalamin (or B12), generating cob(II)alamin in an early step in the cofactor trafficking pathway. Cob(II)alamin is subsequently partitioned to support cellular needs for the synthe
Publikováno v:
Encyclopedia of Inorganic and Bioinorganic Chemistry
Publikováno v:
Biochemistry. 59:1124-1136
ATP:Co(I)rrinoid adenosyltransferases (ACATs) catalyze the transfer of the adenosyl moiety from co-substrate ATP to a corrinoid substrate. ACATs are grouped into three families, namely, CobA, PduO, and EutT. The EutT family of enzymes is further divi
Autor:
Laura D. Elmendorf, Thomas C. Brunold
Publikováno v:
Methods in Enzymology ISBN: 9780323955577
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2cbfdca07bbd8f6aeb41457cfa304566
https://doi.org/10.1016/bs.mie.2022.02.002
https://doi.org/10.1016/bs.mie.2022.02.002
Autor:
Danushka M. Ekanayake, Sergey V. Lindeman, Thomas C. Brunold, Anne A. Fischer, Richard J Jodts, Joshua R Miller, Adam T. Fiedler
Publikováno v:
Inorg Chem
Parallel spectroscopic and computational studies of iron(III) cysteine dioxygenase (CDO) and synthetic models are presented. The synthetic complexes utilize the ligand tris(4,5-diphenyl-1-methylimidazol-2-yl)phosphine ((Ph2)TIP), which mimics the fac