Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Thomas C Williams"'
Autor:
Ashley Akbari, James Farrell, Aziz Sheikh, Ben Goldacre, Alex J Walker, Ewen M Harrison, Laurie A Tomlinson, Ronan Lyons, Sinead Brophy, Jennifer Preston, Colin R Simpson, Nazir I Lone, Louisa Pollock, Annemarie B Docherty, J Kenneth Baillie, Malcolm G Semple, Peter S Hall, Olivia V Swann, Sohan Seth, Thomas C Williams, Srinivasa V Katikireddi, Michael J Seaborne, J. Samantha Ainsworth, Freya F Semple
Publikováno v:
BMJ Open, Vol 12, Iss 11 (2022)
Introduction SARS-CoV-2 infection rarely causes hospitalisation in children and young people (CYP), but mild or asymptomatic infections are common. Persistent symptoms following infection have been reported in CYP but subsequent healthcare use is unc
Externí odkaz:
https://doaj.org/article/cf07730a349e46cca37b328be010fc5c
Autor:
Mark D. Lyttle, Helen Groves, Thomas C. Williams, Simon B. Drysdale, Ian Sinha, Xinxue Liu, Steve Cunningham, Dalia Iskander, Abigail Maxwell-Hodkinson, Shaun O'Hagan, Olivia V. Swann, Chengetai D. Mpamhanga, Damian Roland, Thomas Waterfield, Robin Marlow
Publikováno v:
Wellcome Open Research, Vol 6 (2024)
Background In 2021 we launched the BronchStart study, which collected information on 17,899 presentations in children with serious respiratory tract infections following the release of lockdown restrictions. Our study informed the Joint Committee on
Externí odkaz:
https://doaj.org/article/818e52225723452da626b227fd0f93be
Autor:
Tiina Talts, Lucy G. Mosscrop, David Williams, John S. Tregoning, Whitney Paulo, Arinder Kohli, Thomas C. Williams, Katja Hoschler, Joanna Ellis, Simon de Lusignan, Maria Zambon
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 4 (2024)
ABSTRACTPrevention of respiratory syncytial virus (RSV) infection is now a global health priority, with a long-acting monoclonal antibody and two RSV vaccines recently licenced for clinical use. Most licenced and candidate interventions target the RS
Externí odkaz:
https://doaj.org/article/b3898c91b7de4407be54ac9d4b238011
Autor:
Mario Hönemann, Melanie Maier, Armin Frille, Stephanie Thiem, Sandra Bergs, Thomas C. Williams, Vicente Mas, Christoph Lübbert, Corinna Pietsch
Publikováno v:
Viruses, Vol 16, Iss 6, p 943 (2024)
Following an interseasonal rise in mainly pediatric respiratory syncytial virus (RSV) cases in Germany in 2021, an exceptionally high number of adult cases was observed in the subsequent respiratory season of 2022/2023. The aim of this study was to c
Externí odkaz:
https://doaj.org/article/d0a9393445e348e8ad8a2dfc2ff3197d
Autor:
Alexander C. Carpenter, Adam M. Feist, Fergus S.M. Harrison, Ian T. Paulsen, Thomas C. Williams
Publikováno v:
Metabolic Engineering Communications, Vol 17, Iss , Pp e00227- (2023)
Adaptive Laboratory Evolution (ALE) is a powerful tool for engineering and understanding microbial physiology. ALE relies on the selection and enrichment of mutations that enable survival or faster growth under a selective condition imposed by the ex
Externí odkaz:
https://doaj.org/article/9cda84a8ff8247b3962bd063e0d29514
Autor:
Xin Xu, Felix Meier, Benjamin A. Blount, Isak S. Pretorius, Tom Ellis, Ian T. Paulsen, Thomas C. Williams
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Naturally evolved genomes tend to be unnecessarily large and redundant, and are not optimised for biotechnological or research applications. In this review, the authors explore genome minimization and re-functionalisation approaches, and discuss thei
Externí odkaz:
https://doaj.org/article/b48e29581c2f49e99b9a9fd76a69f807
Publikováno v:
Biotechnology for Biofuels, Vol 12, Iss 1, Pp 1-14 (2019)
Abstract Background Propionic acid (PA), a key platform chemical produced as a by-product during petroleum refining, has been widely used as a food preservative and an important chemical intermediate in many industries. Microbial PA production throug
Externí odkaz:
https://doaj.org/article/bbe52e2a79e44b03b851ffa294dc56ef
Publikováno v:
BMC Pediatrics, Vol 18, Iss 1, Pp 1-12 (2018)
Abstract Background An estimated 11% of births occur preterm, and survival is improving. Early studies suggested an association between preterm birth and earlier puberty. Given the adverse outcomes associated with early puberty this could have signif
Externí odkaz:
https://doaj.org/article/c07edd24ef084c2b857c1f6c8d1e74ff
Publikováno v:
ACS synthetic biology. 11(8)
The global expansion of biomanufacturing is currently limited by the availability of sugar-based microbial feedstocks, which require farmland for cultivation and therefore cannot support large increases in production without impacting the human food
Autor:
Victoria Holdstock, Jonathan Twynam-Perkins, Timothy Bradnock, Elizabeth M Dickson, Kathleen Harvey-Wood, Pota Kalima, Jill King, William J Olver, Mustafa Osman, Atul Sabharwal, Andrew Smith, Stefan Unger, Louisa Pollock, Ross Langley, Philip Davies, Thomas C Williams
Publikováno v:
The Lancet Infectious Diseases. 23:154-156