Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Thomas C Schulz"'
Autor:
Thomas C Schulz, Holly Y Young, Alan D Agulnick, M Josephine Babin, Emmanuel E Baetge, Anne G Bang, Anindita Bhoumik, Igor Cepa, Rosemary M Cesario, Carl Haakmeester, Kuniko Kadoya, Jonathan R Kelly, Justin Kerr, Laura A Martinson, Amanda B McLean, Mark A Moorman, Janice K Payne, Mike Richardson, Kelly G Ross, Eric S Sherrer, Xuehong Song, Alistair Z Wilson, Eugene P Brandon, Chad E Green, Evert J Kroon, Olivia G Kelly, Kevin A D'Amour, Allan J Robins
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37004 (2012)
Development of a human embryonic stem cell (hESC)-based therapy for type 1 diabetes will require the translation of proof-of-principle concepts into a scalable, controlled, and regulated cell manufacturing process. We have previously demonstrated tha
Externí odkaz:
https://doaj.org/article/217b85207ea64dde8656ee24573940b2
Autor:
Lyndon M. West, Allan J. Robins, Amanda B. McLean, Rian J. Meginley, Thomas C. Schulz, Prasoon Gupta
Publikováno v:
Marine Drugs, Vol 10, Iss 8, Pp 1662-1670 (2012)
Two new briarane diterpenoids briareolate esters J (1) and K (2) were isolated from the methanolic extract of the octocoral Briareum asbestinum collected off the coast of Boca Raton, Florida. The structures of briaranes 1 and 2 were elucidated by int
Externí odkaz:
https://doaj.org/article/1c7eff2ff380498596154bf68d64f5e3
Autor:
Daniel A. Bartlett, Korey A. Wilson, Xiaowen Lyu, Rachel Patton McCord, Peiyao A. Zhao, David M. Gilbert, Zhaohui S. Qin, Allan J. Robins, Vishnu Dileep, Ben Li, Thomas C. Schulz, Victor G. Corces, Axel Poulet, Stephen Dalton, Claire Marchal, Michael Kulik, Juan Carlos Rivera-Mulia, Job Dekker
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Vol 13, Iss 1, Pp 193-206 (2019)
Stem Cell Reports, Vol 13, Iss 1, Pp 193-206 (2019)
Summary The temporal order of DNA replication is regulated during development and is highly correlated with gene expression, histone modifications and 3D genome architecture. We tracked changes in replication timing, gene expression, and chromatin co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7e2e295c8e62050b2ff2afe8ee1a0b2
https://doi.org/10.1016/j.stemcr.2019.05.021
https://doi.org/10.1016/j.stemcr.2019.05.021
Autor:
Thomas C. Schulz
Publikováno v:
Stem Cells Translational Medicine. 4:927-931
The cellular component of ViaCyte's VC-01 combination product for type 1 diabetes, pancreatic endoderm cells (PEC-01) derived from CyT49 human embryonic stem cells, matures after transplantation and functions to regulate blood glucose in rodent model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9b8350751fef2962fdacf379d2c67eb
https://doi.org/10.5966/sctm.2015-0058
https://doi.org/10.5966/sctm.2015-0058
Autor:
Thomas C. Schulz, Amanda B. McLean, Allan J. Robins, Prasoon Gupta, Upasana Sharma, Lyndon M. West
Publikováno v:
Journal of Natural Products. 75:1223-1227
Three new bicyclic C(21) terpenoids, clathric acid (1) and two N-acyl taurine derivatives, clathrimides A (2) and B (3), were isolated from the marine sponge Clathria compressa. The structures of these compounds were elucidated by interpretation of s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::391efce7020ae9bc67f5436503fa88bc
https://doi.org/10.1021/np300265p
https://doi.org/10.1021/np300265p
Autor:
Eric S. Sherrer, Amanda B. McLean, Upasana Sharma, Allan J. Robins, Prasoon Gupta, Lyndon M. West, Thomas C. Schulz
Publikováno v:
Organic Letters. 13:3920-3923
Three new briarane diterpenoids, briareolate esters L-N (1-3), have been isolated from a gorgonian Briareum asbestinum. Briareolate esters L (1) and M (2) are the first natural products possessing a 10-membered macrocyclic ring with a (E,Z)-dieneone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b036a4d73af76281874f844d5bad5e3
https://doi.org/10.1021/ol201443k
https://doi.org/10.1021/ol201443k
Autor:
Stephen Dalton, David M. Gilbert, Tyrone Ryba, Michael Kulik, Allan J. Robins, Mari Itoh, Junjie Lu, Ichiro Hiratani, Jinfeng Zhang, Thomas C. Schulz
Publikováno v:
Genome Research. 20:761-770
To identify evolutionarily conserved features of replication timing and their relationship to epigenetic properties, we profiled replication timing genome-wide in four human embryonic stem cell (hESC) lines, hESC-derived neural precursor cells (NPCs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::077707c4a822e4a05ca2fb261e5e6dc6
https://doi.org/10.1101/gr.099655.109
https://doi.org/10.1101/gr.099655.109
Autor:
Nissim Benvenisty, Minal Patel, Glyn Stacey, Lesley Young, Sanna Vuoristo, Barak Blum, Robert Passier, Steve Oh, Rebecca S. Hamilton, Miodrag Stojkovic, Barbara B. Knowles, Benjamin Reubinoff, Kehkooi Kee, Barbara S. Mallon, Andras Nagy, Michal Amit, Janet Rossant, Paul J. Gokhale, Franck Lebrin, Henrike Siemen, Simon Bevan, Weidong Zhang, Milla Mikkola, Stephen L. Minger, Norio Nakatsuji, Peter W. Andrews, Eric S Sherrer, Paul Bello, Tikva Turetsky, Lorraine S. Berry, Behrouz Aflatoonian, Christine L. Mummery, Masha Mileikovsky, Yoav Mayshar, Angela Ford, Harry Moore, Mark Jones, Joseph Itskovitz-Eldor, Jackie Johnson, Lars Ährlund-Richter, Roland A. Fleck, Oluseun Adewumi, Jamie P. Jackson, Alex Hampl, Andre Bh Choo, Petr Dvorak, Timo Otonkoski, Daisy Manning, Henrik Semb, Marta P. Imreh, Justin Brooking, Marina Gertsenstein, Dorien Ward, Jin P. Szatkiewicz, Timo Tuuri, Thomas C Schulz, Marian S Piekarczyk, Kevin G. Chen, Karin Astrid Maria Gertow, Renee A. Reijo Pera, Thomas A Weaver, Gemma Beighton, Kye-Yoon Park, Majlinda Lako, Ronald D.G. McKay, Katarina Emanuelsson, Cia Olsson, Carmel M. O’Brien, Johan Hyllner, Hema Patel, Outi Hovatta, Allan J. Robins, Hirofumi Suemori, Peter J. Rugg-Gunn, Martin F. Pera, Marie Corbel, Gary A. Churchill, Ivan Damjanov, John S Draper, Benjamin L. King, Lyn Healy, Steineke van den Brink, Roger A. Pedersen, Anna E. Michalska, Kristina Vintersten
Publikováno v:
Nature Biotechnology. 25:803-816
The International Stem Cell Initiative characterized 59 human embryonic stem cell lines from 17 laboratories worldwide. Despite diverse genotypes and different techniques used for derivation and maintenance, all lines exhibited similar expression pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::867a067cc25cab7204dd3712d4e89593
https://doi.org/10.1038/nbt1318
https://doi.org/10.1038/nbt1318
Autor:
David M. Gilbert, Jared Zimmerman, Tamer Kahveci, Kristopher L. Nazor, Michael Kulik, Haitham Gabr, Zheng Lian, Allan J. Robins, Jeanne F. Loring, Sherman M. Weissman, Quinton Buckley, Laura Menendez, Ruth Didier, Juan Carlos Rivera-Mulia, Thomas C. Schulz, Stephen Dalton, Takayo Sasaki
Duplication of the genome in mammalian cells occurs in a defined temporal order referred to as its replication-timing (RT) program. RT changes dynamically during development, regulated in units of 400–800 kb referred to as replication domains (RDs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ae645c3c6d126d50927e769b30149f1
https://europepmc.org/articles/PMC4509994/
https://europepmc.org/articles/PMC4509994/
Autor:
Smita Savant-Bhonsale, Eliza Wickham Garcia, Ying Liu, Rodolfo Gonzalez, Marina Bibikova, Jian-Bing Fan, Aparna Khanna, Allan J. Robins, Thomas C. Schulz, Todd W. Plaia, Padmavathy Vanguri, Jeremy M. Crook, Dan E. Arking, Bruce Davidson, Mahendra S. Rao, Soojung Shin, Lixin Zhou, Johan Hyllner, Eugene Chudin, Aravinda Chakravarti, Peter Sartipy, Alan K. Smith, Bonnie Wu, Jonathan M. Auerbach, David L. Barker, Jeanne F. Loring, Anirban Maitra
Publikováno v:
Genome Research. 16:1075-1083
Human embryonic stem (hES) cells originate during an embryonic period of active epigenetic remodeling. DNA methylation patterns are likely to be critical for their self-renewal and pluripotence. We compared the DNA methylation status of 1536 CpG site
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01a009918186f6a05e71db7b3fc6d830
https://doi.org/10.1101/gr.5319906
https://doi.org/10.1101/gr.5319906