Zobrazeno 1 - 10
of 214
pro vyhledávání: '"Thomas C Foster"'
Publikováno v:
Frontiers in Aging Neuroscience, Vol 8 (2016)
Cognitive function depends on transcription; however, there is little information linking altered gene expression to impaired prefrontal cortex function during aging. Young and aged F344 rats were characterized on attentional set shift and spatial me
Externí odkaz:
https://doaj.org/article/a63a64ec37e74fa7b96e7e8f4cf682ff
Autor:
Sarah eGuadiana, Alexander eParker, Gileno F Filho, Ashton eSequeira, Susan eRowland, Gerry eShaw, Ron eMandel, Thomas C Foster, Ashok eKumar, Matthew eSarkisian
Publikováno v:
Frontiers in Aging Neuroscience, Vol 8 (2016)
The primary cilia of forebrain neurons assemble around birth and become enriched with neuromodulatory receptors. Our understanding of the permanence of these structures and their associated signaling pathways in the aging brain is poor, but they are
Externí odkaz:
https://doaj.org/article/71f1badbdf3f492cb10b5f43f86697cd
Publikováno v:
Frontiers in Aging Neuroscience, Vol 6 (2014)
The spatial water maze is routinely used to investigate hippocampal-dependent spatial memory and the biological mechanisms that underlie variability in cognitive decline during aging. The utility of the task for repeated testing in order to examine t
Externí odkaz:
https://doaj.org/article/c58fa4a54f7d4b3e8398c53dcef33a94
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
There are sex differences in vulnerability and resilience to the stressors of aging and subsequent age-related cognitive decline. Cellular senescence occurs as a response to damaging or stress-inducing stimuli. The response includes a state of irreve
Externí odkaz:
https://doaj.org/article/b105104a5d394f09ab5acc7231aa9874
Autor:
Thomas C Foster
Publikováno v:
Frontiers in Aging Neuroscience, Vol 4 (2012)
Externí odkaz:
https://doaj.org/article/4e2f2ec3f32e4f429145e706c15b5c44
Autor:
Gene E Alexander, Lee eRyan, Dawn eBowers, Thomas C Foster, Jennifer L Bizon, David S Geldmacher, Elizabeth L Glisky
Publikováno v:
Frontiers in Aging Neuroscience, Vol 4 (2012)
With the population of older adults expected to grow rapidly over the next two decades, it has become increasingly important to advance research efforts to elucidate the mechanisms associated with cognitive aging, with the ultimate goal of developing
Externí odkaz:
https://doaj.org/article/33a71587dbb94376aa3b5cf0690507a1
Publikováno v:
Frontiers in Aging Neuroscience, Vol 4 (2012)
Executive functions supported by prefrontal cortical systems provide essential control and planning mechanisms to guide goal-directed behavior. As such, age-related alterations in executive functions can mediate profound and widespread deficits on a
Externí odkaz:
https://doaj.org/article/a7a6e311558d4e54bb0181413a91decd
Autor:
Erik D Roberson, R. Anthony DeFazio, Carol A. Barnes, Gene E. Alexander, Jennifer L. Bizon, Dawn eBowers, Thomas C Foster, Elizabeth L. Glisky, Bonnie E. Levin, Lee eRyan, Clinton B. Wright, David S. Geldmacher
Publikováno v:
Frontiers in Aging Neuroscience, Vol 4 (2012)
The gradual decline of cognitive ability with age, even in the absence of overt brain disease, is a growing problem. Although cognitive aging is a common and feared accompaniment of the aging process, its underlying mechanisms are not well understood
Externí odkaz:
https://doaj.org/article/c51a5ca5046d46368cf49bd9342fbfad
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51385 (2012)
We previously demonstrated that aged ovariectomized rats that had received prior estradiol treatment in middle-age exhibited increased levels of estrogen receptor alpha (ERα) in the hippocampus as well as enhanced hippocampal dependent memory as com
Externí odkaz:
https://doaj.org/article/7e37e43b28834987a60586a40c041007
Autor:
Jessica A. Peterson, Larissa J. Strath, Chavier Laffitte Nodarse, Asha Rani, Zhiguang Huo, Lingsong Meng, Sean Yoder, James H. Cole, Thomas C. Foster, Roger B. Fillingim, Yenisel Cruz-Almeida
Publikováno v:
Epigenetics, Vol 17, Iss 13, Pp 2178-2187 (2022)
Chronic musculoskeletal pain is a health burden that may accelerate the aging process. Accelerated brain aging and epigenetic aging have separately been observed in those with chronic pain. However, it is unknown whether these biological markers of a
Externí odkaz:
https://doaj.org/article/aae0aa138060444e9da2fe3e33601a46