Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Thomas C Donaghey"'
Autor:
Jamie H Rosenblum Lichtenstein, Yi-Hsiang Hsu, Igor M Gavin, Thomas C Donaghey, Ramon M Molina, Khristy J Thompson, Chih-Lin Chi, Bruce S Gillis, Joseph D Brain
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126926 (2015)
Molds can cause respiratory symptoms and asthma. We sought to use isolated peripheral blood mononuclear cells (PBMCs) to understand changes in cytokine and chemokine levels in response to mold and mycotoxin exposures and to link these levels with res
Externí odkaz:
https://doaj.org/article/3182905021f5486abf3615337c1d48de
Autor:
Georgios Pyrgiotakis, Nagarjun V. Konduru, Jessica-Miranda Bustamante, Laura S. Van Winkle, Joseph D. Brain, Zhenyuan Zhang, Patricia C. Edwards, Thomas C. Donaghey, Akira Tsuda, Phillip Demokritou
Do immature lungs have air-blood barriers that are more permeable to inhaled nanoparticles than those of fully developed mature lungs? Data supporting this notion and explaining the underlying mechanisms do not exist as far as we know. Using a rat mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9080b163bd86853fe2ac1c167b86f74
https://europepmc.org/articles/PMC6929694/
https://europepmc.org/articles/PMC6929694/
Autor:
Philip Demokritou, Glen M. DeLoid, Joseph D. Brain, Thomas C. Donaghey, Johnatan Padovez Gonçalves, Ramon M. Molina, Leonardo Z. Pipek
Publikováno v:
NanoImpact
Cellulose nanofibers (CNF) reduced serum triglyceride levels in rats when co-administered with heavy cream by gavage. Do CNF and other nanomaterials (NMs) alter the tissue distribution and retention of co-administered metal ions? We evaluated whether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8334d35eb9360c3ed79d982465fe4ddf
https://doi.org/10.1016/j.impact.2020.100279
https://doi.org/10.1016/j.impact.2020.100279
Autor:
Joseph D. Brain, Yi-Hsiang Hsu, Jamie H. Rosenblum Lichtenstein, Joel A. Mathews, Bruce S. Gillis, Andre Bordini, Thomas C. Donaghey, Jin-Ah Park, John J. Godleski, David I. Kasahara, Ramon M. Molina
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 55:521-531
After a single or multiple intratracheal instillations of Stachybotrys chartarum (S. chartarum or black mold) spores in BALB/c mice, we characterized cytokine production, metabolites, and inflammatory patterns by analyzing mouse bronchoalveolar lavag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1b0356a4d19b986fbd0028df783dec0
https://doi.org/10.1165/rcmb.2015-0291oc
https://doi.org/10.1165/rcmb.2015-0291oc
Autor:
Joseph D. Brain, Priscila de Moura Queiroz, Ramon M. Molina, Sylvia Rodrigues, Thomas C. Donaghey, Christa Watson-Wright
Publikováno v:
Experimental lung research. 44(4-5)
AIM OF STUDY: Metal contaminants contribute to adverse human health effects via acute and chronic exposures. Acute metal exposures followed by prolonged secondary metal exposures may elicit exaggerated inflammatory responses in certain individuals. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c31213df774579bdf055e6e2cab3e08e
https://pubmed.ncbi.nlm.nih.gov/30295553
https://pubmed.ncbi.nlm.nih.gov/30295553
Autor:
Flavia Damiani, Philip Demokritou, Svetla Stoilova-McPhie, Ramon M. Molina, Thomas C. Donaghey, Jason S. Tresback, Georgios Pyrgiotakis, Joseph D. Brain, Nagarjun V. Konduru
We explored the influence of nanoparticle (NP) surface charge and hydrophobicity on NP—biomolecule interactions by measuring the composition of adsorbed phospholipids on four NPs, namely, positively charged CeO(2) and ZnO and negatively charged BaS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e36b5420275930c1ecced8ef09ddd31
https://europepmc.org/articles/PMC6507429/
https://europepmc.org/articles/PMC6507429/
Autor:
Philip Demokritou, Joseph D. Brain, Archana Swami, Paulo Lin, Nagarjun V. Konduru, Thomas C. Donaghey, Georgios Pyrgiotakis, Silke Krol, Flavia Damiani, Ramon M. Molina, Wolfgang G. Kreyling, Patrizia Andreozzi
Publikováno v:
Part. Fibre Toxicol. 14:42 (2017)
Particle and Fibre Toxicology, Vol 14, Iss 1, Pp 1-12 (2017)
Particle and Fibre Toxicology
Particle and Fibre Toxicology, Vol 14, Iss 1, Pp 1-12 (2017)
Particle and Fibre Toxicology
BACKGROUND: We previously showed that cerium oxide (CeO2), barium sulfate (BaSO4) and zinc oxide (ZnO) nanoparticles (NPs) exhibited different lung toxicity and pulmonary clearance in rats. We hypothesize that these NPs acquire coronas with different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69eea8b3f4179d9285b17248f7b57764
https://doi.org/10.1186/s12989-017-0223-3
https://doi.org/10.1186/s12989-017-0223-3
Autor:
Christa Watson, Joseph D. Brain, Thomas C. Donaghey, Sylvia Rodrigues, Ramon M. Molina, Jamie H. Rosenblum Lichtenstein, Sumati Ram-Mohan, Ramaswamy Krishnan, Priscila de Moura Queiroz, Flavia Damiani
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 150(1)
To assess chemical toxicity, current high throughput screening (HTS) assays rely primarily on in vitro measurements using cultured cells. Responses frequently differ from in vivo results due to the lack of physical and humoral interactions provided b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19589050ade2378479feb4d26b64e2ce
https://pubmed.ncbi.nlm.nih.gov/26719368
https://pubmed.ncbi.nlm.nih.gov/26719368
Publikováno v:
Environmental Pollution. 182:217-224
We correlated mineralogical and particle characteristics of Zn-containing particles with Zn geoavailability, bioaccessibility, and bioavailability following gavage and intranasal (IN) administration in rats. We compared samples of Zn/Pb mine waste an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a919b34f17dfd012f316766c5788a0ed
https://doi.org/10.1016/j.envpol.2013.07.013
https://doi.org/10.1016/j.envpol.2013.07.013
Autor:
Joseph D. Brain, Thomas C. Donaghey, Hugo Hirano, Benoit Adamo, Nagarjun V. Konduru, Ramon M. Molina, Georgios Pyrgiotakis, Brendan Laurenzi
Publikováno v:
Inhalation toxicology. 28(12)
Particles can be delivered to the respiratory tract of animals using various techniques. Inhalation mimics environmental exposure but requires large amounts of aerosolized NPs over a prolonged dosing time, varies in deposited dose among individual an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea716a19d7c632e21db8f6569fd9f525
https://pubmed.ncbi.nlm.nih.gov/27618878
https://pubmed.ncbi.nlm.nih.gov/27618878