Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Thomas C Boothby"'
Autor:
Shraddha KC, Kenny H Nguyen, Vincent Nicholson, Annie Walgren, Tony Trent, Edith Gollub, Paulette Sofia Romero-Perez, Alex S Holehouse, Shahar Sukenik, Thomas C Boothby
Publikováno v:
eLife, Vol 13 (2024)
The conformational ensemble and function of intrinsically disordered proteins (IDPs) are sensitive to their solution environment. The inherent malleability of disordered proteins, combined with the exposure of their residues, accounts for this sensit
Externí odkaz:
https://doaj.org/article/68e5334fa09a44b89622454bfe66b813
Publikováno v:
eLife, Vol 13 (2024)
Tiny animals known as tardigrades use a combination of DNA repair machinery and a novel protein to mend their genome after intense ionizing radiation.
Externí odkaz:
https://doaj.org/article/c748d4f614704b1ba818af822a64ce41
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
The disaccharide trehalose is a synergistic cosolute and key biomarker of desiccation tolerance in tardigrades.
Externí odkaz:
https://doaj.org/article/a7ee0d341c234f4f9dbdabfcc6cc1305
Autor:
Ilaria Giovannini, Thomas C. Boothby, Michele Cesari, Bob Goldstein, Roberto Guidetti, Lorena Rebecchi
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Water unavailability is an abiotic stress causing unfavourable conditions for life. Nevertheless, some animals evolved anhydrobiosis, a strategy allowing for the reversible organism dehydration and suspension of metabolism as a direct respon
Externí odkaz:
https://doaj.org/article/576329eb994c485e82ed1695695cab08
Publikováno v:
BMC Microbiology, Vol 20, Iss 1, Pp 1-13 (2020)
Abstract Background Anhydrobiotes, such as the yeast Saccharomyces cerevisiae, are capable of surviving almost total loss of water. Desiccation tolerance requires an interplay of multiple events, including preserving the protein function and membrane
Externí odkaz:
https://doaj.org/article/5640d9b794804be88043f6a3c291b5fa
Autor:
Cherie Hesgrove, Thomas C. Boothby
Publikováno v:
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-15 (2020)
Abstract Disordered proteins have long been known to help mediate tolerance to different abiotic stresses including freezing, osmotic stress, high temperatures, and desiccation in a diverse set of organisms. Recently, three novel families of intrinsi
Externí odkaz:
https://doaj.org/article/22af78abf11f490391ed9222d6612d47
Autor:
Thomas C. Boothby
Publikováno v:
EvoDevo, Vol 10, Iss 1, Pp 1-12 (2019)
Abstract When animals are exposed to an extreme environmental stress, one of three possible outcomes takes place: the animal dies, the animal avoids the environmental stress and survives, or the animal tolerates the environmental stress and survives.
Externí odkaz:
https://doaj.org/article/8405c77fc03a422ab07c13af43977962
Autor:
Jerry A. Holmberg, Stephen M. Henry, Thierry Burnouf, Dana Devine, Susanne Marschner, Thomas C. Boothby, Scott R. Burger, Stella T. Chou, Brian Custer, Neil Blumberg, Donald L. Siegel, Steven L. Spitalnik
Publikováno v:
Transfusion. 62:2391-2404
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e137558a926c125deb0690a63089840
https://doi.org/10.1111/trf.17092
https://doi.org/10.1111/trf.17092
Autor:
Maxwell H. Packebush, Silvia Sanchez-Martinez, Sourav Biswas, Shraddha KC, Kenny H. Nguyen, John F. Ramirez, Vincent Nicholson, Thomas C. Boothby
Publikováno v:
Scientific Reports. 13
Biologics, pharmaceuticals containing or derived from living organisms, such as vaccines, antibodies, stem cells, blood, and blood products are a cornerstone of modern medicine. However, nearly all biologics have a major deficiency: they are inherent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2222fa11568686ce4e7a7b9bfa4e6c7
https://doi.org/10.1038/s41598-023-31586-9
https://doi.org/10.1038/s41598-023-31586-9
Autor:
Maxwell H. Packebush, Silvia Sanchez-Martinez, Sourav Biswas, KC Shraddha, Kenny Nguyen, Thomas C. Boothby
Biologics, pharmaceuticals containing or derived from living organisms, such as vaccines, antibodies, stem cells, blood, and blood products are a cornerstone of modern medicine. However, nearly all biologics have a major deficiency: they are inherent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cdf2a885508e24eb4d0010b11b58633
https://doi.org/10.1101/2022.11.28.518276
https://doi.org/10.1101/2022.11.28.518276
