Zobrazeno 1 - 10
of 251
pro vyhledávání: '"Thomas C, Friedrich"'
Autor:
Tulika Singh, Itzayana G. Miller, Sravani Venkatayogi, Helen Webster, Holly J. Heimsath, Josh A. Eudailey, Dawn M. Dudley, Amit Kumar, Riley J. Mangan, Amelia Thein, Matthew T. Aliota, Christina M. Newman, Mariel S. Mohns, Meghan E. Breitbach, Madison Berry, Thomas C. Friedrich, Kevin Wiehe, David H. O'Connor, Sallie R. Permar
Publikováno v:
mBio, Vol 15, Iss 3 (2024)
ABSTRACT Immunodominant and highly conserved flavivirus envelope proteins can trigger cross-reactive IgG antibodies against related flaviviruses, which shapes subsequent protection or disease severity. This study examined how prior dengue serotype 3
Externí odkaz:
https://doaj.org/article/496d519ecdd14e718fa10a683dc6b9bf
Autor:
Michael W Grunst, Hwi Min Gil, Andres G Grandea, Brian J Snow, Raiees Andrabi, Rebecca Nedellec, Iszac Burton, Natasha M Clark, Sanath Kumar Janaka, Nida K Keles, Ryan V Moriarty, Andrea M Weiler, Saverio Capuano, Christine M Fennessey, Thomas C Friedrich, Shelby L O'Connor, David H O'Connor, Aimee T Broman, Brandon F Keele, Jeffrey D Lifson, Lars Hangartner, Dennis R Burton, David T Evans
Publikováno v:
PLoS Pathogens, Vol 20, Iss 1, p e1011819 (2024)
Fc-mediated antibody effector functions, such as antibody-dependent cellular cytotoxicity (ADCC), can contribute to the containment HIV-1 replication but whether such activities are sufficient for protection is unclear. We previously identified an an
Externí odkaz:
https://doaj.org/article/8f8b7d273bab487cb298ce773438920f
Autor:
Emma C Boehm, Anna S Jaeger, Hunter J Ries, David Castañeda, Andrea M Weiler, Corina C Valencia, James Weger-Lucarelli, Gregory D Ebel, Shelby L O'Connor, Thomas C Friedrich, Mostafa Zamanian, Matthew T Aliota
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 10, p e0011674 (2023)
A promising candidate for arbovirus control and prevention relies on replacing arbovirus-susceptible Aedes aegypti populations with mosquitoes that have been colonized by the intracellular bacterium Wolbachia and thus have a reduced capacity to trans
Externí odkaz:
https://doaj.org/article/bacbba45b99b4ed289a48a08606de945
Autor:
Olivia E Harwood, Lea M Matschke, Ryan V Moriarty, Alexis J Balgeman, Abigail J Weaver, Amy L Ellis-Connell, Andrea M Weiler, Lee C Winchester, Courtney V Fletcher, Thomas C Friedrich, Brandon F Keele, David H O'Connor, Jessica D Lang, Matthew R Reynolds, Shelby L O'Connor
Publikováno v:
PLoS Pathogens, Vol 19, Iss 9, p e1011676 (2023)
Sustainable HIV remission after antiretroviral therapy (ART) withdrawal, or post-treatment control (PTC), remains a top priority for HIV treatment. We observed surprising PTC in an MHC-haplomatched cohort of MHC-M3+ SIVmac239+ Mauritian cynomolgus ma
Externí odkaz:
https://doaj.org/article/4923447812844a0a8eb8bb1afde9858e
Autor:
Nicholas P. Krabbe, Elaina Razo, Hunter J. Abraham, Rachel V. Spanton, Yujia Shi, Saswati Bhattacharya, Ellie K. Bohm, Julia C. Pritchard, Andrea M. Weiler, Ann M. Mitzey, Jens C. Eickhoff, Eric Sullivan, John C. Tan, Matthew T. Aliota, Thomas C. Friedrich, David H. O’Connor, Thaddeus G. Golos, Emma L. Mohr
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionZika virus (ZIKV) infection during pregnancy results in a spectrum of birth defects and neurodevelopmental deficits in prenatally exposed infants, with no clear understanding of why some pregnancies are more severely affected. Differentia
Externí odkaz:
https://doaj.org/article/fc3e7c5657814d8791677bf87f7d1787
Autor:
Michelle R Koenig, Ann M Mitzey, Xiankun Zeng, Leticia Reyes, Heather A Simmons, Terry K Morgan, Ellie K Bohm, Julia C Pritchard, Jenna A Schmidt, Emily Ren, Fernanda B Leyva Jaimes, Eva Winston, Puja Basu, Andrea M Weiler, Thomas C Friedrich, Matthew T Aliota, Emma L Mohr, Thaddeus G Golos
Publikováno v:
PLoS Pathogens, Vol 19, Iss 8, p e1011274 (2023)
Zika virus (ZIKV) can be transmitted vertically from mother to fetus during pregnancy, resulting in a range of outcomes including severe birth defects and fetal/infant death. Potential pathways of vertical transmission in utero have been proposed but
Externí odkaz:
https://doaj.org/article/e28b7219fce54b63b1bf6e6e718f3ad3
Autor:
Mitchell D. Ramuta, Christina M. Newman, Savannah F. Brakefield, Miranda R. Stauss, Roger W. Wiseman, Amanda Kita-Yarbro, Eli J. O’Connor, Neeti Dahal, Ailam Lim, Keith P. Poulsen, Nasia Safdar, John A. Marx, Molly A. Accola, William M. Rehrauer, Julia A. Zimmer, Manjeet Khubbar, Lucas J. Beversdorf, Emma C. Boehm, David Castañeda, Clayton Rushford, Devon A. Gregory, Joseph D. Yao, Sanjib Bhattacharyya, Marc C. Johnson, Matthew T. Aliota, Thomas C. Friedrich, David H. O’Connor, Shelby L. O’Connor
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Air surveillance offers a potential means of monitoring airborne pathogens without the need for individual sampling. Here, the authors perform continuous air sampling in 15 community settings in the US for 29 weeks and demonstrate its feasibility for
Externí odkaz:
https://doaj.org/article/2b085b42cb1041bb95275d470a2ada17
Autor:
Katherine A. Amato, Luis A. Haddock, Katarina M. Braun, Victoria Meliopoulos, Brandi Livingston, Rebekah Honce, Grace A. Schaack, Emma Boehm, Christina A. Higgins, Gabrielle L. Barry, Katia Koelle, Stacey Schultz-Cherry, Thomas C. Friedrich, Andrew Mehle
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Transmission of influenza A viruses (IAV) between hosts and replication within host impose genetic bottlenecks, constraining viral diversity and adaptation. Here, Amato et al. perform site-specific inoculation of barcoded IAV of ferrets and track vir
Externí odkaz:
https://doaj.org/article/d3cb8e6727e14346a2d7c30f2568dc31
Frequent first-trimester pregnancy loss in rhesus macaques infected with African-lineage Zika virus.
Autor:
Jenna R Rosinski, Lauren E Raasch, Patrick Barros Tiburcio, Meghan E Breitbach, Phoenix M Shepherd, Keisuke Yamamoto, Elaina Razo, Nicholas P Krabbe, Mason I Bliss, Alexander D Richardson, Morgan A Einwalter, Andrea M Weiler, Emily L Sneed, Kerri B Fuchs, Xiankun Zeng, Kevin K Noguchi, Terry K Morgan, Alexandra J Alberts, Kathleen M Antony, Sabrina Kabakov, Karla K Ausderau, Ellie K Bohm, Julia C Pritchard, Rachel V Spanton, James N Ver Hoove, Charlene B Y Kim, T Michael Nork, Alex W Katz, Carol A Rasmussen, Amy Hartman, Andres Mejia, Puja Basu, Heather A Simmons, Jens C Eickhoff, Thomas C Friedrich, Matthew T Aliota, Emma L Mohr, Dawn M Dudley, David H O'Connor, Christina M Newman
Publikováno v:
PLoS Pathogens, Vol 19, Iss 3, p e1011282 (2023)
In the 2016 Zika virus (ZIKV) pandemic, a previously unrecognized risk of birth defects surfaced in babies whose mothers were infected with Asian-lineage ZIKV during pregnancy. Less is known about the impacts of gestational African-lineage ZIKV infec
Externí odkaz:
https://doaj.org/article/9603e93a993b481b9b1de7a38cf4ca26
Autor:
Michelle R Koenig, Ann M Mitzey, Terry K Morgan, Xiankun Zeng, Heather A Simmons, Andres Mejia, Fernanda Leyva Jaimes, Logan T Keding, Chelsea M Crooks, Andrea M Weiler, Ellie K Bohm, Matthew T Aliota, Thomas C Friedrich, Emma L Mohr, Thaddeus G Golos
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0284964 (2023)
BackgroundCongenital Zika virus (ZIKV) infection can result in birth defects, including malformations in the fetal brain and visual system. There are two distinct genetic lineages of ZIKV: African and Asian. Asian-lineage ZIKVs have been associated w
Externí odkaz:
https://doaj.org/article/ad69e4377e494c85b2ba523b7e1ca04f