Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Thomas Bukur"'
Autor:
Nikolai Schleussner, Pierre Cauchy, Vedran Franke, Maciej Giefing, Oriol Fornes, Naveen Vankadari, Salam A. Assi, Mariantonia Costanza, Marc A. Weniger, Altuna Akalin, Ioannis Anagnostopoulos, Thomas Bukur, Marco G. Casarotto, Frederik Damm, Oliver Daumke, Benjamin Edginton-White, J. Christof M. Gebhardt, Michael Grau, Stephan Grunwald, Martin-Leo Hansmann, Sylvia Hartmann, Lionel Huber, Eva Kärgel, Simone Lusatis, Daniel Noerenberg, Nadine Obier, Ulrich Pannicke, Anja Fischer, Anja Reisser, Andreas Rosenwald, Klaus Schwarz, Srinivasan Sundararaj, Andre Weilemann, Wiebke Winkler, Wendan Xu, Georg Lenz, Klaus Rajewsky, Wyeth W. Wasserman, Peter N. Cockerill, Claus Scheidereit, Reiner Siebert, Ralf Küppers, Rudolf Grosschedl, Martin Janz, Constanze Bonifer, Stephan Mathas
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Disease-causing mutations in genes encoding transcription factors (TFs) can affect TF interactions with their cognate DNA-binding motifs. Whether and how TF mutations impact upon the binding to TF composite elements (CE) and the interaction
Externí odkaz:
https://doaj.org/article/89617bbfc2d9437a8c22b2474e5ec08c
Publikováno v:
Brain and Spine, Vol 3, Iss , Pp 102116- (2023)
Externí odkaz:
https://doaj.org/article/284f72c179aa423cb384a2ce93d05920
Autor:
Thomas Bukur, Pablo Riesgo-Ferreiro, Patrick Sorn, Ranganath Gudimella, Johannes Hausmann, Thomas Rösler, Martin Löwer, Barbara Schrörs, Ugur Sahin
Publikováno v:
Viruses, Vol 15, Iss 6, p 1391 (2023)
Background: The outbreak of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) resulted in the global COVID-19 pandemic. The urgency for an effective SARS-CoV-2 vaccine has led to the development of the first series of vaccines at unpre
Externí odkaz:
https://doaj.org/article/a052a53a25a84b7aaa9a0b2eac1e543d
Autor:
Vinzenz Särchen, Lisa Marie Reindl, Sara Wiedemann, Senthan Shanmugalingam, Thomas Bukur, Julia Becker, Martin Suchan, Evelyn Ullrich, Meike Vogler
Publikováno v:
Cells, Vol 12, Iss 6, p 906 (2023)
Although the overall survival in pediatric rhabdomyosarcoma (RMS) has increased over the last decades, the most aggressive subtype of alveolar RMS is in dire need of novel treatment strategies. RMS cells evade cell death induction and immune control
Externí odkaz:
https://doaj.org/article/09fafa2ac250487fb27749fce316188b
Autor:
Barbara Schrörs, Pablo Riesgo-Ferreiro, Patrick Sorn, Ranganath Gudimella, Thomas Bukur, Thomas Rösler, Martin Löwer, Ugur Sahin
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0249254 (2021)
Due to the widespread of the COVID-19 pandemic, the SARS-CoV-2 genome is evolving in diverse human populations. Several studies already reported different strains and an increase in the mutation rate. Particularly, mutations in SARS-CoV-2 spike-glyco
Externí odkaz:
https://doaj.org/article/37f08c2151554ad79d9100c6ddc74c9a
Autor:
Sara Becker, Annette Fink, Jürgen Podlech, Irina Giese, Julia K. Schmiedeke, Thomas Bukur, Matthias J. Reddehase, Niels A. Lemmermann
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Murine cytomegalovirus (mCMV) codes for MHC class-I trafficking modulators m04/gp34, m06/gp48, and m152/gp40. By interacting with the MHC class-Iα chain, these proteins disconnect peptide-loaded MHC class-I (pMHC-I) complexes from the constitutive v
Externí odkaz:
https://doaj.org/article/c237d69e45f24517b9089c80522eb416
Autor:
Barbara Schrörs, Sebastian Boegel, Christian Albrecht, Thomas Bukur, Valesca Bukur, Christoph Holtsträter, Christoph Ritzel, Katja Manninen, Arbel D. Tadmor, Mathias Vormehr, Ugur Sahin, Martin Löwer
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Background: Tumor models are critical for our understanding of cancer and the development of cancer therapeutics. The 4T1 murine mammary cancer cell line is one of the most widely used breast cancer models. Here, we present an integrated map of the g
Externí odkaz:
https://doaj.org/article/a4d91ac8c0444717b82ad54389e39553
Autor:
Nadja Salomon, Fulvia Vascotto, Abderaouf Selmi, Mathias Vormehr, Juliane Quinkhardt, Thomas Bukur, Barbara Schrörs, Martin Löewer, Mustafa Diken, Özlem Türeci, Ugur Sahin, Sebastian Kreiter
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
Antigen-encoding, lipoplex-formulated RNA (RNA-LPX) enables systemic delivery to lymphoid compartments and selective expression in resident antigen-presenting cells. We report here that the rejection of CT26 tumors, mediated by local radiotherapy (LR
Externí odkaz:
https://doaj.org/article/3e5a60314c6a4287a58876c10a7472b0
Publikováno v:
BMC Medical Genomics, Vol 11, Iss 1, Pp 1-12 (2018)
Abstract Background The presentation of HLA peptide complexes to T cells is a highly regulated and tissue specific process involving multiple transcriptionally controlled cellular components. The extensive polymorphism of HLA genes and the complex co
Externí odkaz:
https://doaj.org/article/0e31c173a1ef4fa595c68594e1cb9c3d
Autor:
Christian Grunwitz, Nadja Salomon, Fulvia Vascotto, Abderaouf Selmi, Thomas Bukur, Mustafa Diken, Sebastian Kreiter, Özlem Türeci, Ugur Sahin
Publikováno v:
OncoImmunology, Vol 8, Iss 9 (2019)
HPV16 infections are associated with a variety of cancers and there is compelling evidence that the transforming activity of HPV16 critically depends on the expression of the viral oncoproteins E6 and E7. Therapeutic cancer vaccines capable of genera
Externí odkaz:
https://doaj.org/article/21ba36e27494446595238e26cdfe2b56