Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Thomas Broggini"'
Publikováno v:
Brain and Spine, Vol 3, Iss , Pp 102098- (2023)
Externí odkaz:
https://doaj.org/article/e9a1a297496448419da03a9520392246
Autor:
Maximilian Geissler, Weiyi Jia, Emine Nisanur Kiraz, Ida Kulacz, Xiao Liu, Adrian Rombach, Vincent Prinz, Daniel Jussen, Konstantinos D. Kokkaliaris, Hind Medyouf, Lisa Sevenich, Marcus Czabanka, Thomas Broggini
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 12, p 10055 (2023)
Metastasis, particularly brain metastasis, continues to puzzle researchers to this day, and exploring its molecular basis promises to break ground in developing new strategies for combatting this deadly cancer. In recent years, the research focus has
Externí odkaz:
https://doaj.org/article/719ab18e91514638a7f64c2e98dc17e6
Publikováno v:
Life, Vol 12, Iss 5, p 691 (2022)
Vascular guidance is critical in developmental vasculogenesis and pathological angiogenesis. Brain tumors are strongly vascularized, and antiangiogenic therapy was anticipated to exhibit a strong anti-tumor effect in this tumor type. However, vascula
Externí odkaz:
https://doaj.org/article/c9b35fed154f4e5eba08a508c071c2a3
Autor:
Lena Stange, Kristin Elizabeth Lucia, Adnan Ghori, Peter Vajkoczy, Marcus Czabanka, Thomas Broggini
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 6, p 3108 (2022)
Despite intensive research, glioblastoma remains almost invariably fatal. Various promising drugs targeting specific aspects of glioma biology, in addition to or as an alternative to antiproliferative chemotherapy, were not successful in larger clini
Externí odkaz:
https://doaj.org/article/758e40b5ddfc4ad99391c63d42414c0c
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Objective: Spinal metastatic disease remains a major problem of oncological diseases. Patients affected may suffer pain, spinal instability, and severe neurological deficits. Today, palliative surgery and radiotherapy are the mainstays of therapy. In
Externí odkaz:
https://doaj.org/article/39125c90b2214955b5de15adf061f325
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 3, p 1679 (2022)
EphrinB2–EphB4 signaling is critical during embryogenesis for cardiovascular formation and neuronal guidance. Intriguingly, critical expression patterns have been discovered in cancer pathologies over the last two decades. Multiple connections to t
Externí odkaz:
https://doaj.org/article/51f7795ef0ac4ca8b1dd30adc07989c9
Autor:
Andras Piffko, Thomas Broggini, Christoph Harms, Ralf Heinrich Adams, Peter Vajkoczy, Marcus Czabanka
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 15, p 8028 (2021)
Tumor–endothelial cell interactions represent an essential mechanism in spinal metastasis. Ephrin-B2–EphB4 communication induces tumor cell repulsion from the endothelium in metastatic melanoma, reducing spinal bone metastasis formation. To shed
Externí odkaz:
https://doaj.org/article/a2d422e7e8164b1cb7a937ecd4a5db0e
Autor:
Thomas Broggini, Andras Piffko, Christian J Hoffmann, Christoph Harms, Peter Vajkoczy, Marcus Czabanka
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162540 (2016)
During the metastatic process tumor cells circulate in the blood stream and are carried to various organs. In order to spread to different organs tumor cell-endothelial cell interactions are crucial for extravasation mechanisms. It remains unclear if
Externí odkaz:
https://doaj.org/article/e96a5b604bdb4ae7baebc97ca1aeee81
Autor:
Iftach Shaked, Conrad Foo, Rui Liu, Yingying Cui, Xiang Ji, Thomas Broggini, Philipp Mächler, Prithu Sundd, Anna Devor, Beth Friedman, David Kleinfeld
How transient hyperglycemia contributes to cerebro-vascular disease has been a challenge to study under controlled conditions. We present an approach to model luminal vessel thrombo-inflammation using amplified, ultrashort laser-pulses to physically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::535eaf863291307fee11d7598b35c489
https://doi.org/10.1101/2022.08.10.503527
https://doi.org/10.1101/2022.08.10.503527
Autor:
Thomas Broggini, Ralf H. Adams, Marcus Czabanka, Christian J. Hoffmann, Andras Piffko, Peter Vajkoczy, Christoph Harms, Adnan Ghori
Publikováno v:
Oncogene. 39:7063-7075
Metastases account for the majority of cancer deaths. Bone represents one of the most common sites of distant metastases, and spinal bone metastasis is the most common source of neurological morbidity in cancer patients. During metastatic seeding of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b26a551efac79a06559e4dd4a27c8a5f
https://doi.org/10.1038/s41388-020-01473-y
https://doi.org/10.1038/s41388-020-01473-y