Zobrazeno 1 - 10
of 507
pro vyhledávání: '"Thomas Bradley"'
Autor:
Carolin M. Sauer, James A. Hall, Dominique-Laurent Couturier, Thomas Bradley, Anna M. Piskorz, Jacob Griffiths, Ashley Sawle, Matthew D. Eldridge, Philip Smith, Karen Hosking, Marika A. V. Reinius, Lena Morrill Gavarró, Anne-Marie Mes-Masson, Darren Ennis, David Millan, Aoisha Hoyle, Iain A. McNeish, Mercedes Jimenez-Linan, Filipe Correia Martins, Julia Tischer, Maria Vias, James D. Brenton
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract High-grade serous ovarian carcinoma (HGSOC) is characterised by poor outcome and extreme chromosome instability (CIN). Therapies targeting centrosome amplification (CA), a key mediator of chromosome missegregation, may have significant clini
Externí odkaz:
https://doaj.org/article/2dec6d7efd4243ae9b8168a692f69967
Autor:
Philip Smith, Thomas Bradley, Lena Morrill Gavarró, Teodora Goranova, Darren P. Ennis, Hasan B. Mirza, Dilrini De Silva, Anna M. Piskorz, Carolin M. Sauer, Sarwah Al-Khalidi, Ionut-Gabriel Funingana, Marika A. V. Reinius, Gaia Giannone, Liz-Anne Lewsley, Jamie Stobo, John McQueen, Gareth Bryson, Matthew Eldridge, The BriTROC Investigators, Geoff Macintyre, Florian Markowetz, James D. Brenton, Iain A. McNeish
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract The drivers of recurrence and resistance in ovarian high grade serous carcinoma remain unclear. We investigate the acquisition of resistance by collecting tumour biopsies from a cohort of 276 women with relapsed ovarian high grade serous car
Externí odkaz:
https://doaj.org/article/1ccafbd33afa4d399a8e68fd7523c12c
Publikováno v:
Environmental Research: Energy, Vol 1, Iss 3, p 035012 (2024)
Greenhouse gas emissions from burning fossil fuels, including the predominant energy generation method in many countries, coal power plants, face challenges resulting from the pursuit of climate policy. Modelling performed by intergovernmental organi
Externí odkaz:
https://doaj.org/article/a6ec07124432477291dd60f2cc95108c
Autor:
Philip Smith, Thomas Bradley, Lena Morrill Gavarró, Teodora Goranova, Darren P. Ennis, Hasan B. Mirza, Dilrini De Silva, Anna M. Piskorz, Carolin M. Sauer, Sarwah Al-Khalidi, Ionut-Gabriel Funingana, Marika A. V. Reinius, Gaia Giannone, Liz-Anne Lewsley, Jamie Stobo, John McQueen, Gareth Bryson, Matthew Eldridge, The BriTROC Investigators, Geoff Macintyre, Florian Markowetz, James D. Brenton, Iain A. McNeish
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/7fa144d3f1d843cdbc178d67b28d1d98
Autor:
Tomas Kazda, Deanna H. Pafundi, Alan Kraling, Thomas Bradley, Val J. Lowe, Debra H. Brinkmann, Nadia N. Laack
Publikováno v:
Physics and Imaging in Radiation Oncology, Vol 6, Iss , Pp 94-100 (2018)
Background and purpose: The amino-acid positron emission tomography (PET) tracer 3,4-dihydroxy-6-[18F] fluoro-l-phenylalanine (18F-DOPA) has increased sensitivity for detecting regions of biologically aggressive tumors compared to T1 contrast-enhance
Externí odkaz:
https://doaj.org/article/6829e94b17874e419a8bd886e8a575f0
Publikováno v:
Energies, Vol 14, Iss 17, p 5240 (2021)
Electric vehicle (EV) charging infrastructure is present all over the United States, but charging prices vary greatly, both in amount and in the methods by which they are assessed. For this paper, we interpret and analyze charging price information f
Externí odkaz:
https://doaj.org/article/305614c7a0dd4b409953359eaf80171c
Publikováno v:
Leukemia Research Reports, Vol 4, Iss 1, Pp 36-38 (2015)
Pregnancy in women with paroxysmal nocturnal hemoglobinuria (PNH) is associated with increased maternal and fetal morbidity and mortality. There is limited published experience regarding therapy of PNH during pregnancy. We describe a case of a 30 yea
Externí odkaz:
https://doaj.org/article/7097aea9c0e04ec9b753b537a731ea4c
Publikováno v:
Biologics: Targets & Therapy, Vol 2008, Iss Issue 4, Pp 789-811 (2008)
Kit L Cheng, Thomas Bradley, Daniel R Budman1Monter Cancer Center, North Shore – LIJ Health Systems, Lake Success, New York, USAAbstract: Epothilones are a new class of antimicrotubule agents currently in clinical trials. Their chemical structures
Externí odkaz:
https://doaj.org/article/72e05137839c4d13b14316ea5a51b046
Publikováno v:
Oncology Reviews, Vol 3, Iss 2 (2011)
Drug delivery systems for the therapeutic use of cytotoxic chemotherapy are an essential aspect of successful treatment and remain under active evaluation. Such systems offer advantages such as they can change the pharmacologic and pharmacodynamic pr
Externí odkaz:
https://doaj.org/article/cf76f3ca59b948eea88d08edd8d391d4
Autor:
Jensen, Stephanie, Sanderfer, Van Christian, Porter, Kierstin, Rieker, Madeline G, Maniscalco, Brianna R., Lloyd, Jenna, Gallagher, Robert, Wang, Huaping, Ross, Sam, Lauer, Cynthia, Cunningham, Kyle, Thomas, Bradley
Publikováno v:
In Injury July 2024 55(7)