Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Thomas Biederer"'
Autor:
Sandra Sanchez-Roige, Mariela V. Jennings, Hayley H. A. Thorpe, Jazlene E. Mallari, Lieke C. van der Werf, Sevim B. Bianchi, Yuye Huang, Calvin Lee, Travis T. Mallard, Samuel A. Barnes, Jin Yi Wu, Amanda M. Barkley-Levenson, Ely C. Boussaty, Cedric E. Snethlage, Danielle Schafer, Zeljana Babic, Boyer D. Winters, Katherine E. Watters, Thomas Biederer, andMe Research Team, James Mackillop, David N. Stephens, Sarah L. Elson, Pierre Fontanillas, Jibran Y. Khokhar, Jared W. Young, Abraham A. Palmer
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Impulsivity is a multidimensional heritable phenotype that broadly refers to the tendency to act prematurely and is associated with multiple forms of psychopathology, including substance use disorders. We performed genome-wide association st
Externí odkaz:
https://doaj.org/article/b47ec1bf7cc04d37956dc97a36fdfe9e
Autor:
Karen Perez de Arce, Adema Ribic, Dhrubajyoti Chowdhury, Katherine Watters, Garth J. Thompson, Basavaraju G. Sanganahalli, Elizabeth T. C. Lippard, Astrid Rohlmann, Stephen M. Strittmatter, Markus Missler, Fahmeed Hyder, Thomas Biederer
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
LRRTM1 is a post synaptic adhesion protein, that promotes AMPA receptor mediated synaptic transmission. Here the authors show that LRRTM1 and the adhesion molecule SynCAM 1 act together to organize synapses in the prefrontal cortex with relevance for
Externí odkaz:
https://doaj.org/article/dd39d5faa5084166b39c89b441a273e5
Autor:
Vincent Paget-Blanc, Marlene E. Pfeffer, Marie Pronot, Paul Lapios, Maria-Florencia Angelo, Roman Walle, Fabrice P. Cordelières, Florian Levet, Stéphane Claverol, Sabrina Lacomme, Mélina Petrel, Christelle Martin, Vincent Pitard, Véronique De Smedt Peyrusse, Thomas Biederer, David Perrais, Pierre Trifilieff, Etienne Herzog
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
The neurotransmitter dopamine is an important regulator of brain function. Here the authors describe “dopamine hub synapses”, where dopamine transmission may act in synergy with other neurotransmitters.
Externí odkaz:
https://doaj.org/article/d9419129d0284637921db33ea1d13266
Autor:
Francesca Cucinotta, Arianna Ricciardello, Laura Turriziani, Giorgia Calabrese, Marilena Briguglio, Maria Boncoddo, Fabiana Bellomo, Pasquale Tomaiuolo, Silvia Martines, Marianna Bruschetta, Francesca La Fauci Belponer, Tiziana Di Bella, Costanza Colombi, Marco Baccarin, Chiara Picinelli, Paola Castronovo, Carla Lintas, Roberto Sacco, Thomas Biederer, Barbara Kellam, Stephen W. Scherer, Antonio M. Persico
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 8, Iss 9, Pp n/a-n/a (2020)
Abstract Background Children with autism spectrum disorder (ASD) display impressive clinical heterogeneity, also involving treatment response. Genetic variants can contribute to explain this large interindividual phenotypic variability. Methods Array
Externí odkaz:
https://doaj.org/article/fad1dd81389e4f15bb4c6f2937598d76
Autor:
Adema Ribic, Thomas Biederer
Publikováno v:
Neural Plasticity, Vol 2019 (2019)
Experience remodels cortical connectivity during developmental windows called critical periods. Experience-dependent regulation of synaptic strength during these periods establishes circuit functions that are stabilized as critical period plasticity
Externí odkaz:
https://doaj.org/article/25f59038e72d4930b7f754296f35bf3f
Publikováno v:
Cell Reports, Vol 26, Iss 2, Pp 381-393.e6 (2019)
Summary: Cortical plasticity peaks early in life and tapers in adulthood, as exemplified in the primary visual cortex (V1), wherein brief loss of vision in one eye reduces cortical responses to inputs from that eye during the critical period but not
Externí odkaz:
https://doaj.org/article/37751a32608c43b8a9b03f0486115f11
Autor:
Antonella Pirone, Jonathan M. Alexander, Jenny B. Koenig, Denise R. Cook-Snyder, Medha Palnati, Robert J. Wickham, Lillian Eden, Neha Shrestha, Leon Reijmers, Thomas Biederer, Klaus A. Miczek, Chris G. Dulla, Michele H. Jacob
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 10 (2018)
Autism spectrum disorder (ASD) is a highly prevalent and genetically heterogeneous brain disorder. Developing effective therapeutic interventions requires knowledge of the brain regions that malfunction and how they malfunction during ASD-relevant be
Externí odkaz:
https://doaj.org/article/ee6f2bb4c1464cf5ae2867677d363b46
Autor:
Yehuda Salzberg, Andrew J Coleman, Kevin Celestrin, Moran Cohen-Berkman, Thomas Biederer, Sivan Henis-Korenblit, Hannes E Bülow
Publikováno v:
PLoS Genetics, Vol 13, Iss 1, p e1006579 (2017)
Neurons receive excitatory or sensory inputs through their dendrites, which often branch extensively to form unique neuron-specific structures. How neurons regulate the formation of their particular arbor is only partially understood. In genetic scre
Externí odkaz:
https://doaj.org/article/f4998e0a71ee4fbea6268418a06d7afa
Autor:
Tony Cijsouw, Austin M. Ramsey, TuKiet T. Lam, Beatrice E. Carbone, Thomas A. Blanpied, Thomas Biederer
Publikováno v:
Proteomes, Vol 6, Iss 4, p 48 (2018)
Synapses are specialized neuronal cell-cell contacts that underlie network communication in the mammalian brain. Across neuronal populations and circuits, a diverse set of synapses is utilized, and they differ in their molecular composition to enable
Externí odkaz:
https://doaj.org/article/016703b1c9de4a5c92371d1900ff022d
Autor:
Sandra Sanchez-Roige, Mariela V Jennings, Hayley HA Thorpe, Jazlene Mallari, Lieke C van der Werf, Sevim B Bianchi, Travis T Mallard, Katherine E Watters, Thomas Biederer, Sarah L Elson, Pierre Fontanillas, Jibran Y Khokhar, Jared W Young, Abraham A Palmer
Publikováno v:
European Neuropsychopharmacology. 63:e82-e83