Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Thomas Bickert"'
Autor:
Timo Heckt, Thomas Bickert, Anke Jeschke, Sebastian Seitz, Jochen Schulze, Wulf D Ito, Wolfgang Zimmermann, Michael Amling, Thorsten Schinke, Andrea Kristina Horst, Johannes Keller
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114360 (2014)
Alterations in bone remodeling are a major public health issue, as therapeutic options for widespread bone disorders such as osteoporosis and tumor-induced osteolysis are still limited. Therefore, a detailed understanding of the regulatory mechanism
Externí odkaz:
https://doaj.org/article/6c838fd5aa3346c5ac7ac08bd25aecb9
Autor:
Andrea Mautner, Thorsten Schinke, Lara Duchstein, Robert P. Marshall, Philip Catala-Lehnen, Anke Jeschke, Michaela Schweizer, Michael Amling, Kristofer Wintges, Till Koehne, Benjamin Otto, Sabrina Sieber, Thomas Bickert, Andrea Kristina Horst, Hans-Juergen Kreienkamp
Publikováno v:
The Journal of Immunology. 195:3675-3684
The cytosolic protein Sharpin is a component of the linear ubiquitin chain assembly complex, which regulates NF-κB signaling in response to specific ligands, such as TNF-α. Its inactivating mutation in chronic proliferative dermatitis mutation (Cpd
Autor:
Tobias Polte, Gesine Hansen, Claudia M. Trujillo-Vargas, Gisela Wohlleben, Tobias A. Oelschlaeger, Klaus J. Erb, Matthias J. Duechs, Thomas Bickert
Publikováno v:
International Archives of Allergy and Immunology. 149:219-230
Background: Recent clinical trials, epidemiological studies and animal experiments have suggested that probiotics may help suppress the development of allergic responses. Objective: To investigate whether the application of the probiotic Escherichia
Autor:
Josef Thalhamer, Thomas Bickert, Richard Weiss, Sandra Scheiblhofer, Ulrike Richardt, Bernhard Fleischer, Uwe Ritter
Publikováno v:
Vaccine. 25:25-33
Experimental leishmaniasis represents a suitable model to analyze Th1-type associated immunity. In C57BL/6 mice healing of leishmaniasis correlates with activation of Th1 cells. Recently, it could be demonstrated that dermal dendritic cells rather th
Autor:
Klaus J. Erb, Christian Reiser, Thomas Bickert, Claus Ruehland, Claudia M. Trujillo-Vargas, Juergen Hess, Marc Brinkman, Gisela Wohlleben
Publikováno v:
Medical Microbiology and Immunology. 196:31-39
We analysed the effects of murine polyomavirus-like particles (PLPs) on bone marrow-derived dendritic cells (BMDCs) and T cells in vitro. BMDCs activated with PLPs up-regulated CD40, CD80, CD86 and major histocompatibility complex (MHC) class II surf
Autor:
K. D. Mayer, Susanne M. Grunewald, Tobias Polte, G. Hansen, Claudia M. Trujillo-Vargas, Klaus J. Erb, Gisela Wohlleben, Thomas Bickert, José R. Ramírez-Pineda, Alois Palmetshofer
Publikováno v:
Clinical Experimental Allergy. 35:1003-1013
Summary Background Allergen-induced T-helper type 2 (Th2) responses can be inhibited with Th1 directing vaccines. However, studies comparing the efficacy of the different adjuvants have not been performed in detail. Objective For this reason we compa
Autor:
Johannes Keller, Thorsten Schinke, Anke Jeschke, Thomas Bickert, Wolfgang Zimmermann, Timo Heckt, Andrea Kristina Horst, Sebastian Seitz, Michael Amling, Wulf D. Ito, Jochen Schulze
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 12, p e114360 (2014)
PLoS ONE, Vol 9, Iss 12, p e114360 (2014)
Alterations in bone remodeling are a major public health issue, as therapeutic options for widespread bone disorders such as osteoporosis and tumor-induced osteolysis are still limited. Therefore, a detailed understanding of the regulatory mechanism
Autor:
Robert P. Marshall, Ziyang Zhang, Mascha Binder, Michael Amling, Christoph Wagener, Peter Ludewig, Andrea Kristina Horst, Wolfgang Rottbauer, Thomas Bickert, Wulf D. Ito, Anna Klinke
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 32(11)
Objective— Previously, we demonstrated the relevance for endothelial carcinoembryonic antigen−related cell adhesion molecule 1 (CEACAM1) expression in collateral formation. However, a proarteriogenic role for CEACAM1 + myeloid cells is unknown. H
Autor:
Thorsten Schinke, Johannes Keller, Michael Amling, Jochen Schulze, Philip Catala-Lehnen, Kristofer Wintges, Andrea Kristina Horst, Thomas Bickert, Wulf D. Ito
Publikováno v:
Biochemical and biophysical research communications. 417(1)
Interleukin-33 (IL-33) is the most recently identified member of the IL-1 family of cytokines, which is primarily known for its proinflammatory functions. We have previously reported that IL-33 is expressed by bone-forming osteoblasts, and that admin
Autor:
Andrew N. J. McKenzie, André Gessner, Alexander S. Spiro, Tim N. Hissnauer, Mario M. Zaiss, Thorsten Schinke, Thomas Streichert, Thomas Bickert, Kristofer Wintges, Joachim Albers, Georg Schett, F. Timo Beil, Michael Amling, Andrea Kristina Horst, Kristin Klaetschke, Johannes Keller, Jochen Schulze
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 26(4)
Since the hematopoetic system is located within the bone marrow, it is not surprising that recent evidence has demonstrated the existence of molecular interactions between bone and immune cells. While interleukin 1 (IL-1) and IL-18, two cytokines of