Výsledky vyhledávání - "Thomas B. Clarkson"

Akademický článek

Estradiol Treatment Initiated Early After Ovariectomy Regulates Myocardial Gene Expression and Inhibits Diastolic Dysfunction in Female Cynomolgus Monkeys: Potential Roles for Calcium Homeostasis and Extracellular Matrix Remodeling

Autor: Kristofer T. Michalson, Leanne Groban, Timothy D. Howard, Carol A. Shively, Areepan Sophonsritsuk, Susan E. Appt, J. Mark Cline, Thomas B. Clarkson, J. Jeffrey Carr, Dalane W. Kitzman, Thomas C. Register

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 21 (2018)

Background Left ventricular (LV) diastolic dysfunction often precedes heart failure with preserved ejection fraction, the dominant form of heart failure in postmenopausal women. The objective of this study was to determine the effect of oral estradio

Externí odkaz: https://doaj.org/article/4a1ba9d5740344c885ebb677183efc56

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Akademický článek

Consumption of Mediterranean versus Western Diet Leads to Distinct Mammary Gland Microbiome Populations

Autor: Carol A. Shively, Thomas C. Register, Susan E. Appt, Thomas B. Clarkson, Beth Uberseder, Kenysha Y.J. Clear, Adam S. Wilson, Akiko Chiba, Janet A. Tooze, Katherine L. Cook

Publikováno v: Cell Reports, Vol 25, Iss 1, Pp 47-56.e3 (2018)

Summary: Recent identification of a mammary gland-specific microbiome led to studies investigating bacteria populations in breast cancer. Malignant breast tumors have lower Lactobacillus abundance compared with benign lesions, implicating Lactobacill

Externí odkaz: https://doaj.org/article/191077a29093483eadc9546181b01aaa

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Akademický článek

Lipid metabolism in pigeon aorta during atherogenesis

Autor: Hugh B. Lofland, Jr., Daniel M. Moury, Carl W. Hoffman, Thomas B. Clarkson

Publikováno v: Journal of Lipid Research, Vol 6, Iss 1, Pp 112-118 (1965)

The development of atherosclerosis has been studied in White Carneau and Show Racer pigeons. The results of analytical studies indicate that the disease process is characterized by the accumulation of various lipids, and especially of sterol esters a

Externí odkaz: https://doaj.org/article/31275327220244adaed5c67bc07b2c0e

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Akademický článek

Studies on the regulation of plasma cholesterol levels in squirrel monkeys of two genotypes

Autor: Hugh B. Lofland, Jr., Thomas B. Clarkson, Richard W. St. Clair, Noel D.M. Lehner

Publikováno v: Journal of Lipid Research, Vol 13, Iss 1, Pp 39-47 (1972)

Certain individual squirrel monkeys (“hyporesponders”) are able to remain normocholesterolemic when fed diets containing cholesterol (0.5 mg/kcal). Other squirrel monkeys (“hyperresponders”) when fed the same diet become hypercholesterolemic.

Externí odkaz: https://doaj.org/article/f11b78b7e0f843e69d24f696aa70015b

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Akademický článek

Composition and synthesis of fatty acids in atherosclerotic aortas of the pigeon

Autor: Richard W. St. Clair, Hugh B. Lofland, Jr., Thomas B. Clarkson

Publikováno v: Journal of Lipid Research, Vol 9, Iss 6, Pp 739-747 (1968)

The composition, synthesis, and esterification of fatty acids were studied in aortas of White Carneau and Show Racer pigeons after perfusion of the aortas with a medium containing acetate-1-14C.For both breeds of pigeons the principal change in aorti

Externí odkaz: https://doaj.org/article/b80bd5e7dd4d44abb4bb2dbeaa331dc7

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Association between coronary artery vitamin D receptor expression and select systemic risks factors for coronary artery atherosclerosis

Autor: Thomas C. Register, David M. O’Sullivan, R Xie, P F Schnatz, Jay R. Kaplan, Thomas B. Clarkson, Xuezhi Jiang, Matthew Nudy, S.E. Appt

Publikováno v: Climacteric. 25:369-375

OBJECTIVE The aim of this study is to analyze the association between coronary artery vitamin D receptor (VDR) expression and systemic coronary artery atherosclerosis (CAA) risk factors. METHODS Female cynomolgus monkeys (n = 39) consumed atherogenic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb50776e22ce204cbbfcb262bac517ce
https://doi.org/10.1080/13697137.2021.1985992

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Psychosocial stress increases risk for type 2 diabetes in female cynomolgus macaques consuming a western diet

Autor: Marnie G. Silverstein-Metzler, Brett M. Frye, Jamie N. Justice, Thomas B. Clarkson, Susan E. Appt, J. Jeffrey Carr, Thomas C. Register, Mays Albu-Shamah, Hossam A. Shaltout, Carol A. Shively

Publikováno v: Psychoneuroendocrinology

Chronic psychosocial stress is associated with increased risk of many chronic diseases including type 2 diabetes mellitus. However, it is difficult to establish a causal relationship between stress and diabetes in human studies because stressors ofte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84f007ee802316b283ed407a2694e1b0
https://doi.org/10.1016/j.psyneuen.2022.105706

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