Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Thomas B. Clarke"'
Autor:
Alexander Y. G. Yip, Olivia G. King, Oleksii Omelchenko, Sanjana Kurkimat, Victoria Horrocks, Phoebe Mostyn, Nathan Danckert, Rohma Ghani, Giovanni Satta, Elita Jauneikaite, Frances J. Davies, Thomas B. Clarke, Benjamin H. Mullish, Julian R. Marchesi, Julie A. K. McDonald
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract The intestine is the primary colonisation site for carbapenem-resistant Enterobacteriaceae (CRE) and serves as a reservoir of CRE that cause invasive infections (e.g. bloodstream infections). Broad-spectrum antibiotics disrupt colonisation r
Externí odkaz:
https://doaj.org/article/dfbcc9d5a51c4088979906aa338bfd0e
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
Emulsions are critical across a broad spectrum of industries. Here authors demonstrate a mechanism of spontaneous droplet formation, where the interfacial solute flux promotes droplet formation at the liquid-liquid interface when a phase transfer age
Externí odkaz:
https://doaj.org/article/caf294e84e1f4746b0e106dd64ab4114
Autor:
Aran Singanayagam, Joseph Footitt, Matthias Marczynski, Giorgia Radicioni, Michael T. Cross, Lydia J. Finney, Maria-Belen Trujillo-Torralbo, Maria Calderazzo, Jie Zhu, Julia Aniscenko, Thomas B. Clarke, Philip L. Molyneaux, Nathan W. Bartlett, Miriam F. Moffatt, William O. Cookson, Jadwiga Wedzicha, Christopher M. Evans, Richard C. Boucher, Mehmet Kesimer, Oliver Lieleg, Patrick Mallia, Sebastian L. Johnston
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 8 (2022)
The respiratory tract surface is protected from inhaled pathogens by a secreted layer of mucus rich in mucin glycoproteins. Abnormal mucus accumulation is a cardinal feature of chronic respiratory diseases, but the relationship between mucus and path
Externí odkaz:
https://doaj.org/article/8bada2e2d7bf4317a4dc8b248c77d273
Autor:
Kam Pou Ha, Rebecca S. Clarke, Gyu-Lee Kim, Jane L. Brittan, Jessica E. Rowley, Despoina A. I. Mavridou, Dane Parker, Thomas B. Clarke, Angela H. Nobbs, Andrew M. Edwards
Publikováno v:
mBio, Vol 11, Iss 6 (2020)
ABSTRACT To cause infection, Staphylococcus aureus must withstand damage caused by host immune defenses. However, the mechanisms by which staphylococcal DNA is damaged and repaired during infection are poorly understood. Using a panel of transposon m
Externí odkaz:
https://doaj.org/article/c366ab45cdbd41dbacadbfc7679c2b74
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
The microbiota promotes resistance to respiratory infection through unclear mechanisms. Here, the authors identify members of the gut and upper airway microbiota that protect against respiratory infection by Streptococcus pneumoniae and Klebsiella pn
Externí odkaz:
https://doaj.org/article/42f80173d6014fef9e269abc5d8866a0
Autor:
Akshay Sabnis, Katheryn LH Hagart, Anna Klöckner, Michele Becce, Lindsay E Evans, R Christopher D Furniss, Despoina AI Mavridou, Ronan Murphy, Molly M Stevens, Jane C Davies, Gérald J Larrouy-Maumus, Thomas B Clarke, Andrew M Edwards
Publikováno v:
eLife, Vol 10 (2021)
Colistin is an antibiotic of last resort, but has poor efficacy and resistance is a growing problem. Whilst it is well established that colistin disrupts the bacterial outer membrane (OM) by selectively targeting lipopolysaccharide (LPS), it was uncl
Externí odkaz:
https://doaj.org/article/f64d8e9c4ae644fe8acd8e4ffd54da30
Publikováno v:
Chemical Science. 14:2336-2341
The collision of two or more water microdroplets adsorbed on an electrified surface has been tracked by ECL imaging, uncovering the dynamic complexity of the resulting water microdroplet.
Publikováno v:
Advanced Materials Technologies.
Autor:
Thomas B. Clarke, Jeffrey E. Dick
Publikováno v:
J Phys Chem Lett
Chemistry in confined volumes, such as aqueous droplets, is different from bulk, continuous water. However, few techniques are available to probe interfacial reactivity in complex, multiphase environments. Here, we demonstrate preferential electrored
Publikováno v:
Journal of Chemical Education. 98:2927-2936
Over 200 years ago, Alessandro Volta published his observations of a steady voltage when a piece of electrolyte-soaked cardboard was sandwiched between two dissimilar metals. This observation initiated a century of argument as to the origin of voltai