Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Thomas B. Bolton"'
Autor:
Thomas B. Bolton, Iliyana V. Ivanova, Lubomir T. Lubomirov, Duridanova Db, Hristo Gagov, Rudolf Schubert
Publikováno v:
Experimental Physiology. 92:1037-1046
The aim of this study was to investigate the effect of CART peptide on cardiac performance and on the physiological signalling pathways involved using Rana ridibunda frog heart preparations in vivo. The CART peptide, when injected into the venous sin
Autor:
Oleksandr V. Povstyan, Dmitri V. Gordienko, Ray F. Moss, Maksym I. Harhun, V Pucovský, Thomas B. Bolton
Publikováno v:
Journal of Cellular and Molecular Medicine
This work aimed to establish the lineage of cells similar to the interstitial cells of Cajal (ICC), the arterial ICC-like (AIL) cells, which have recently been described in resistance arteries, and to study their location in the artery wall. Segments
Publikováno v:
British Journal of Pharmacology. 149:179-187
Background and purpose: There is little information about the excitatory cholinergic mechanisms of mouse small intestine although this model is important for gene knock-out studies. Experimental approach: Using patch-clamp techniques, voltage-depende
Autor:
V Pucovský, Thomas B. Bolton
Publikováno v:
Cell Calcium. 39:113-129
Smooth muscle cells (SMCs) contain numerous calcium release domains, grouped into regions discharging as a single unit. Laser scanning confocal microscopy, voltage clamp and immunocytochemistry of single SMCs from small mesenteric arteries of guinea-
Publikováno v:
Neurophysiology. 38:1-8
Using a two-wave fluorescence probe, Fura-2, we studied changes in the intracellular concentration of calcium ions ([Ca2+]i) resulting from activation of muscarinic and purine receptors in single myocytes of the guinea-pig small intestine. Applicatio
Publikováno v:
Journal of Cellular and Molecular Medicine. 9:232-243
Interstitial cells of Cajal are believed to play an important role in gastrointestinal tissues by generating and propagating electrical slow waves to gastrointestinal muscles and/or mediating signals from the enteric nervous system. Recently cells wi
Publikováno v:
Neurophysiology. 36:407-417
A rise in the intracellular concentration of ionized calcium ([Ca2+]i) is a primary signal for contraction in all types of muscles. Recent progress in the development of imaging techniques, with special accent on fluorescence confocal microscopy, and
Publikováno v:
Journal of General Physiology. 123:581-598
There is little information about the mechanisms by which G-protein–coupled receptors gate ion channels although many ionotropic receptors are well studied. We have investigated gating of the muscarinic cationic channel, which mediates the excitato
Autor:
Thomas B. Bolton, Sean P. Parsons
Publikováno v:
The Journal of Physiology. 554:687-705
After enzymatic dispersion of the muscle of the guinea-pig gastric fundus, single elongated cells were observed which differed from archetypal smooth muscle cells due to their knurled, tuberose or otherwise irregular surface morphology. These, but no
Publikováno v:
The Journal of Physiology. 552:119-133
Arterial interstitial cells of Cajal (ICC)-like cells (AIL cells) with a multipolar, irregular, elongated shape and with numerous thin (often less than 1 microm), sometimes branching, processes with lengths up to approximately 60 microm were isolated