Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Thomas B. Barrett"'
Publikováno v:
Pharmacogenomics. 20(17)
Autor:
Erin N Smith, Daniel L Koller, Corrie Panganiban, Szabolcs Szelinger, Peng Zhang, Judith A Badner, Thomas B Barrett, Wade H Berrettini, Cinnamon S Bloss, William Byerley, William Coryell, Howard J Edenberg, Tatiana Foroud, Elliot S Gershon, Tiffany A Greenwood, Yiran Guo, Maria Hipolito, Brendan J Keating, William B Lawson, Chunyu Liu, Pamela B Mahon, Melvin G McInnis, Francis J McMahon, Rebecca McKinney, Sarah S Murray, Caroline M Nievergelt, John I Nurnberger, Evaristus A Nwulia, James B Potash, John Rice, Thomas G Schulze, William A Scheftner, Paul D Shilling, Peter P Zandi, Sebastian Zöllner, David W Craig, Nicholas J Schork, John R Kelsoe
Publikováno v:
PLoS Genetics, Vol 7, Iss 6, p e1002134 (2011)
Although a highly heritable and disabling disease, bipolar disorder's (BD) genetic variants have been challenging to identify. We present new genotype data for 1,190 cases and 401 controls and perform a genome-wide association study including additio
Externí odkaz:
https://doaj.org/article/3c68f3061e9a495589546577b22507ee
Autor:
Christina M. Hultman, Peter R. Schofield, J. Raymond DePaulo, Martin Alda, Szabolcs Szelinger, Susanne Bengesser, Stefan Herms, Alessio Squassina, Gustavo Turecki, Barbara König, Fabian Streit, Jana Strohmaier, Martin Schalling, Maren Lang, Michael McCarthy, Per Hoffmann, Sarah K. Tighe, William Byerley, Jean-Pierre Kahn, Bárbara Arias, Alfonso Tortorella, Francis J. McMahon, William Lawson, Gonzalo Laje, Wade H. Berrettini, Tatyana Shekhtman, Jean-Michel Aubry, Erin N. Smith, Peng Zhang, Stefanie Heilmann-Heimbach, Evaristus A. Nwulia, Thomas B. Barrett, Cinnamon S. Bloss, Nicholas J. Schork, Tatiana Foroud, Antonio Benabarre, Bernhard T. Baune, William Coryell, Giovanni Severino, Sébastien Gard, Michael Bauer, Layla Kassem, Judith A. Badner, Peter P. Zandi, Rebecca McKinney, Paul D. Shilling, Mazda Adli, Pablo Cervantes, John P. Rice, Nirmala Akula, Marcella Rietschel, Maria Grigoroiu-Serbanescu, Armin Birner, David Craig, Caterina Chillotti, Sebastian Kliwicki, Guy A. Rouleau, Alexandre Dayer, Claire Slaney, Thomas Stamm, Piotr M. Czerski, Pamela B. Mahon, Elliot S. Gershon, Susan L. McElroy, Andreas J. Forstner, Sarah E. Bergen, Peter Propping, Johannes Schumacher, Mikael Landén, Marion Leboyer, Janusz K. Rybakowski, Cristiana Cruceanu, Urs Heilbronner, Joanna Hauser, Fernando S. Goes, Howard J. Edenberg, Markus M. Nöthen, Adam Wright, Chunyu Liu, Daniel L. Koller, James B. Potash, Elise T. Bui, Julie Garnham, Caroline M. Nievergelt, William A. Scheftner, Lina Martinsson, Janice M. Fullerton, Maria Del Zompo, Shashi Hitturlingappa, Mirko Manchia, Andreas Reif, Andrea Pfennig, Thomas G. Schulze, Eduard Vieta, Jie Song, Liping Hou, Maria Hipolito, John I. Nurnberger, Louise Frisén, Anna Maaser, Wolfgang Maier, Thomas W. Mühleisen, Andrea Hofmann, Philip B. Mitchell, Clara Brichant-Petitjean, Raffaella Ardau, Joanna M. Biernacka, N. Lackner, Eva Z. Reininghaus, Francesc Colom, Catharina Lavebratt, Francis M. Mondimore, Urban Ösby, Esther Jiménez, Abesh Kumar Bhattacharjee, Marina Mitjans, Tiffany A. Greenwood, Peter Falkai, Stephanie H. Witt, Stéphane Jamain, Sven Cichon, Julia Volkert, Bruno Etain, Lena Backlund, Tomas Novak, Sarah Kittel-Schneider, Franziska Degenhardt, Barbara W. Schweizer, Mark A. Frye, Christian Simhandl, John R. Kelsoe, Sebastian Zöllner, Frank Bellivier, Palmiero Monteleone, Tony Davis, Susan G. Leckband, Mario Maj, Melvin G. McInnis, Pavla Stopkova
Bipolar disorder (BD) is a genetically complex mental illness characterized by severe oscillations of mood and behavior. Genome-wide association studies (GWAS) have identified several risk loci that together account for a small portion of the heritab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eb9a8b135ce3dd73ba545949303e07f
Autor:
Philip B. Mitchell, Clara Brichant-Petitjean, Raffaella Ardau, Peter R. Schofield, Susanne Bengesser, Stefan Herms, Sebastian Zöllner, Christina M. Hultman, Shashi Hitturlingappa, Maria Hipolito, Louise Frisén, Thomas W. Mühleisen, Layla Kassem, Christian Simhandl, Urban Ösby, Frank Bellivier, Peter Falkai, Alessio Squassina, Jana Strohmaier, Esther Jiménez, Palmiero Monteleone, Caterina Chillotti, Stéphane Jamain, Peter P. Zandi, Abesh Kumar Bhattacharjee, Tony Davis, Sarah K. Tighe, William Byerley, Jean-Pierre Kahn, Michael Bauer, Nicholas J. Schork, Joanna Hauser, Andreas J. Forstner, Francis J. McMahon, Peter Propping, Marina Mitjans, Tiffany A. Greenwood, Alfonso Tortorella, Fernando S. Goes, Szabolcs Szelinger, Tomas Novak, Erin N. Smith, Andrea Pfennig, Susan G. Leckband, Pablo Cervantes, Sarah Kittel-Schneider, Sébastien Gard, Adam Wright, Tatiana Foroud, Joanna M. Biernacka, Jean-Michel Aubry, Marcella Rietschel, Elliot S. Gershon, Janusz K. Rybakowski, John R. Kelsoe, Stephanie H. Witt, Elise T. Bui, Sarah E. Bergen, Tatyana Shekhtman, Thomas G. Schulze, Sven Cichon, Julia Volkert, Thomas Stamm, Eduard Vieta, Jie Song, Liping Hou, Markus M. Nöthen, Bruno Etain, Mikael Landén, Caroline M. Nievergelt, Mirko Manchia, William Coryell, Howard J. Edenberg, Andreas Reif, Urs Heilbronner, Gonzalo Laje, Lena Backlund, Wade H. Berrettini, Martin Schalling, Franziska Degenhardt, Susan L. McElroy, Mario Maj, Francis M. Mondimore, Peng Zhang, Stefanie Heilmann-Heimbach, Janice M. Fullerton, Daniel L. Koller, James B. Potash, Michael McCarthy, Barbara W. Schweizer, Rebecca McKinney, Nirmala Akula, Sebastian Kliwicki, Guy A. Rouleau, N. Lackner, William Lawson, Melvin G. McInnis, Eva Z. Reininghaus, Maria Grigoroiu-Serbanescu, Pavla Stopkova, Francesc Colom, Catharina Lavebratt, Judith A. Badner, Mark A. Frye, Alexandre Dayer, Giovanni Severino, Maren Lang, John P. Rice, Per Hoffmann, William A. Scheftner, Lina Martinsson, Pamela B. Mahon, Piotr M. Czerski, Paul D. Shilling, Mazda Adli, Armin Birner, David Craig, Gustavo Turecki, Bárbara Arias, Evaristus A. Nwulia, Thomas B. Barrett, Cinnamon S. Bloss, Marion Leboyer, Chunyu Liu, Maria Del Zompo, Antonio Benabarre, Bernhard T. Baune, Fabian Streit, John I. Nurnberger, Barbara König, Anna Maaser, Wolfgang Maier, Julie Garnham, Claire Slaney, Johannes Schumacher, Cristiana Cruceanu, J. Raymond DePaulo, Martin Alda, Andrea Hofmann
Publikováno v:
Human Molecular Genetics, Vol. 25, No 15 (2016) pp. 3383-3394
Bipolar disorder (BD) is a genetically complex mental illness characterized by severe oscillations of mood and behaviour. Genome-wide association studies (GWAS) have identified several risk loci that together account for a small portion of the herita
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce84533c151df429b5dcbeb04802d6e9
http://hdl.handle.net/11591/395384
http://hdl.handle.net/11591/395384
Autor:
Erin N. Smith, Cinnamon S. Bloss, Tatiana Foroud, Howard J. Edenberg, Paul D. Shilling, David Craig, Sebastian Zöllner, William A. Scheftner, Elliot S. Gershon, John I. Nurnberger, James B. Potash, William Coryell, Peng Zhang, Nicholas J. Schork, Szabolics Szelinger, Melvin G. McInnis, Sherri Liang, Judith A. Badner, Evaristus A. Nwulia, John P. Rice, Thomas B. Barrett, Maria Hipolito, Pamela B. Mahon, William Lawson, Chunyu Liu, Daniel L. Koller, William Byerley, Francis J. McMahon, Wade H. Berrettini, Peter P. Zandi, John R. Kelsoe, Caroline M. Nievergelt, Tiffany A. Greenwood, Thomas G. Schulze, Stephanie Nissen, Rebecca McKinney, Tatyana Shehktman
Publikováno v:
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. :941-950
We have previously reported genome-wide significant linkage of bipolar disorder to a region on 22q12.3 near the marker D22S278. Towards identifying the susceptibility gene, we have conducted a fine-mapping association study of the region in two indep
Autor:
William Lawson, John R. Kelsoe, Sebastian Zöllner, William A. Scheftner, John I. Nurnberger, Eric R. Gamazon, Rebecca McKinney, Thomas B. Barrett, Maria Hipolito, Szabolics Szelinger, Chunling Zhang, Erin N. Smith, Nancy J. Cox, William Byerley, Howard J. Edenberg, Dandan Zhang, Judith A. Badner, Caroline M. Nievergelt, Francis J. McMahon, Thomas G. Schulze, William Coryell, Daniel L. Koller, Nicholas J. Schork, T. Foroud, Melvin G. McInnis, Cinnamon S. Bloss, James B. Potash, Tiffany A. Greenwood, Peng Zhang, Wade H. Berrettini, Peter P. Zandi, Elliot S. Gershon, Lijun Cheng, Chunyu Liu, Paul D. Shilling, David Craig, Evaristus A. Nwulia, Chao Chen, John P. Rice, Pamela B. Mahon
Publikováno v:
Molecular psychiatry
We conducted a systematic study of top susceptibility variants from a genome-wide association (GWA) study of bipolar disorder to gain insight into the functional consequences of genetic variation influencing disease risk. We report here the results o
Autor:
Noah Zaitlen, Sarah S. Murray, Wade H. Berrettini, Peter P. Zandi, James B. Potash, Elliot S. Gershon, Maria Hipolito, Pamela L. Belmonte, Nicholas J. Schork, Howard J. Edenberg, John I. Nurnberger, Evaristus A. Nwulia, Justin Paschall, D. B. Mirel, William Byerley, Francis J. McMahon, William Lawson, Chunyu Liu, Eleazar Eskin, William Coryell, Caroline M. Nievergelt, John P. Rice, Thomas B. Barrett, William A. Scheftner, Corrie B. Panganiban, Judith A. Badner, Erin N. Smith, Sebastian Zöllner, Tatiana Foroud, David Craig, Thomas G. Schulze, Cinnamon S. Bloss, Melvin G. McInnis, Tiffany A. Greenwood, Daniel L. Koller, Falk W. Lohoff, John R. Kelsoe
Publikováno v:
Molecular Psychiatry. 14:755-763
To identify bipolar disorder (BD) genetic susceptibility factors, we conducted two genome-wide association (GWA) studies: one involving a sample of individuals of European ancestry (EA; n=1001 cases; n=1033 controls), and one involving a sample of in
Autor:
William Lawson, Sebastian Zöllner, Peter P. Zandi, Rebecca McKinney, Evaritus A. Nwulia, Tiffany A. Greenwood, Wade H. Berrettini, John I. Nurnberger, William Byerley, Thomas G. Schulze, Maria Hipolito, Elliot S. Gershon, Francis J. McMahon, Ney Alliey-Rodriguez, Erin N. Smith, James B. Potash, Caroline M. Nievergelt, Susan L. Christian, Tatiana Foroud, Szabolics Szelinger, William Sheftner, John P. Rice, Nicholas J. Schork, Dandan Zhang, Pamela L. Belmonte, Melvin G. McInnis, Howard J. Edenberg, David Craig, William Coryell, Cinnamon S. Bloss, Lijun Cheng, Chunyu Liu, Thomas B. Barrett, Daniel L. Koller, John R. Kelsoe, Yudong Qian
Publikováno v:
Molecular Psychiatry. 14:376-380
An overall burden of rare structural genomic variants has not been reported in bipolar disorder (BD), although there have been reports of cases with microduplication and microdeletion. Here, we present a genome-wide copy number variant (CNV) survey o
Publikováno v:
Biological Psychiatry. 64:104-110
Background We have previously reported a single nucleotide polymorphism (P-5, G-384A) in the proximal promoter of the gene for G protein receptor kinase 3 (GRK3) that was associated with bipolar disorder in two independent samples. In this study, we
Autor:
Thomas B. Barrett, Nicholas J. Schork, John E. Emberton, John R. Kelsoe, Sherri G. Liang, Richard L. Hauger, Caroline M. Nievergelt, Eleazar Eskin
Publikováno v:
Psychiatric Genetics. 17:315-322
OBJECTIVES Two genome-wide linkage surveys suggest chromosome 22q12 may contain a susceptibility locus for bipolar disorder (BPD) in the immediate region of the gene G protein receptor kinase-3 (GRK3). We previously published evidence that a single n