Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Thomas B. Aufdemorte"'
Autor:
M.B. Kester, A. J P Yates, R. Walker, G. Favarato, Lynda F. Bonewald, C. Marcelli, Gregory R. Mundy, Brendan F. Boyce, Thomas B. Aufdemorte, B.C. Langton
Publikováno v:
Journal of Bone and Mineral Research. 7:847-853
Transforming growth factor alpha (TGF-alpha) is a polypeptide regulator of cell growth produced by many malignant tumors. It stimulates osteoclastic resorption in bone organ culture and osteoclast-like cell formation in marrow culture. To determine w
Autor:
Theresa L. Chen, Arthur J. Ammann, Lorrie A. McFatridge, Wyne P. Lee, Thomas B. Aufdemorte, L. Steven Beck, Leo Deguzman, Yvette Xu
Publikováno v:
Journal of Bone and Mineral Research. 6:961-968
A single application of recombinant human transforming growth factor beta 1 (rhTGF-beta 1) adjacent to cartilage was found to induce bone formation in rabbit ear full-thickness skin wounds. At doses that optimally promote soft tissue healing, 25-100
Autor:
Felipe Toro, Michael A. Wirth, Carl J. Basamania, Thomas B. Aufdemorte, Donna Korvick, Charles A. Rockwood
Publikováno v:
Journal of Shoulder and Elbow Surgery. 10:140-148
Aseptic loosening of glenoid components is a common problem associated with total shoulder arthroplasty. A new glenoid design aimed at improving fixation outcomes was compared with conventional keeled glenoids in weight-bearing canine shoulders. Radi
Autor:
Thomas B. Aufdemorte, Susan L. Ishaug, Michael J. Yaszemski, Antonios G. Mikos, Rena Bizios, Richard G. Payne
Publikováno v:
Biotechnology and Bioengineering. 50:443-451
We investigated the migration of rat calvaria osteoblast populations on poly(α-hydroxy ester) films for up to 14 days to determine effects of substrate composition and culture conditions on the migratory characteristics of osteoblasts. Initial osteo
Autor:
Thane Morgan, Christoph H. Lohmann, Barbara D. Boyan, Thomas B. Aufdemorte, Bryan P. Brooks, William Ehler, James D. Heckman
Publikováno v:
The Journal of Bone & Joint Surgery. 81:1717-29
Background: The purpose of the present study was to create an effective bone-graft substitute for the treatment of a diaphyseal nonunion. Methods: A standardized nonunion was established in the midportion of the radial diaphysis in thirty mongrel dog
Autor:
Robert C. Thomson, Antonios G. Mikos, Michael J. Miller, Elizabeth Beahm, James C. Lemon, Thomas B. Aufdemorte, William C. Satterfield
Publikováno v:
Biomaterials. 20:2007-2018
A successful tissue engineering method for bone replacement would imitate natural bone graft by providing the essential elements for new bone formation using synthetic scaffolds, osteogenic cell populations, and bone induction factors. This is a stud
Publikováno v:
Journal of Orthopaedic Research. 17:607-614
Recent advances in understanding the biology of fracture healing and the availability of specific macromolecules has resulted in the development of novel treatments for injuries to bone. Fibroblast growth factor-2 or basic fibroblast growth factor (4
Autor:
M. A. Brunsvold, Thomas C. Waldrop, D. R. Miller, Thomas B. Aufdemorte, Brian L Mealey, W. C. Fox
Publikováno v:
Journal of Periodontal Research. 30:404-409
Advances in periodontics with respect to disease activity, microbiology and immunology have demonstrated the multifactorial nature of periodontal diseases. This serves to underscore the need for an ideal animal model for periodontal research. Non-hum
Autor:
Thomas B. Aufdemorte, Howard Dang, Norman Talal, Noriyoshi Ogawa, Howard S Mcguff, Konstantinos Lazaridis
Publikováno v:
Journal of Interferon & Cytokine Research. 15:759-767
Cytokines play a major role in tissue destruction caused by autoimmune dysregulation. In Sjögren's syndrome (SS) patients, salivary glands are the target organs for autoimmune tissue damage. In the present study, reverse transcriptase-polymerase cha
Autor:
Eros S. Chaves, H. Quartuccio, J.G. Seedor, Miron Weinreb, Gideon A. Rodan, Michael A. Brunsvold, Kenneth S. Kornman, Thomas B. Aufdemorte
Publikováno v:
Journal of Periodontal Research. 29:35-40
This study tested the efficacy of alendronate, a bisphosphonate, in reducing alveolar bone loss caused by experimental periodontitis in cynomolgus monkeys. Periodontitis was initiated in adult monkeys by ligating mandibular molar teeth at the cemento