Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Thomas B. Alexander"'
Autor:
Kofi B. Opoku, Teresa Santiago, Priya Kumar, Sophia M. Roush, Yuri Fedoriw, Tamiwe Tomoka, Vasiliki Leventaki, Larissa V. Furtado, Nickhill Bhakta, Thomas B. Alexander, Jeremy R. Wang
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Approximately 80% of pediatric tumors occur in low- and middle-income countries (LMIC), where diagnostic tools essential for treatment decisions are often unavailable or incomplete. Development of cost-effective molecular diagnostics will he
Externí odkaz:
https://doaj.org/article/69d7cfb9f9094a4199bb02c5b072daa6
Autor:
Diriba Fufa Hordofa, Muktar Ahmed, Zewdie Birhanu, Sheila Weitzman, Julie Broas, Aziza Shad, Miguel Bonilla, Thomas B. Alexander
Publikováno v:
PLOS Global Public Health, Vol 4, Iss 7 (2024)
Externí odkaz:
https://doaj.org/article/faf7760748e440e39afc3b5e860b02f8
Autor:
Catherine Habashy, Tatenda T. Yemeke, Nancy S. Bolous, Yichen Chen, Sachiko Ozawa, Nickhill Bhakta, Thomas B. Alexander
Publikováno v:
EClinicalMedicine, Vol 60, Iss , Pp 102005- (2023)
Summary: Background: The stark disparity in survival for children with cancer across the world has inspired a global call to expand chemotherapy access in low and middle income countries. Among the numerous barriers to success, a paucity of reliable
Externí odkaz:
https://doaj.org/article/8477c4e389324222871db78887155bd0
Autor:
Atalay Mulu Fentie, Kaitlyn Buhlinger, Jared Borlagdan, Adam Bernstein, Sheila Weitzman, Wondwessen Bekele, David Korones, Thomas B. Alexander, Julie Broas, Aziza Shad, Ali Mamude Dinkiye, Daniel Hailu, Benyam Muluneh
Publikováno v:
Blood Advances, Vol 3, Iss , Pp 16-19 (2019)
Externí odkaz:
https://doaj.org/article/4161fb2fdcd74ddc873af2d8fc7d3717
Autor:
Jeremy Wang, Nickhill Bhakta, Vanessa Ayer Miller, Mahler Revsine, Mark R. Litzow, Elisabeth Paietta, Yuri Fedoriw, Kathryn G. Roberts, Zhaohui Gu, Charles G. Mullighan, Corbin D. Jones, Thomas B. Alexander
Publikováno v:
JCO Precis Oncol
PURPOSE Most cases of pediatric acute leukemia occur in low- and middle-income countries, where health centers lack the tools required for accurate diagnosis and disease classification. Recent research shows the robustness of using unbiased short-rea
Autor:
Wendy Stock, Thomas B. Alexander, Charles G. Mullighan, Amanda Jacobson, Su Young Kim, Lindsey Rosenwinkel, Deeksha Vishwamitra, Jeremy A. Ross, Yan Sun, John C. Pesko, Bo Tong, Michelle Schmidt, Mohamed Badawi, Chunxu Qu, Yaqi Zhao, Kathryn G. Roberts, Joseph T. Opferman, Robin Norris, Ryan J. Mattison, Shaun A. Fleming, Seong Lin Khaw, Susan I. Colace, Jessica Leonard, Theodore W. Laetsch, Ashish Bajel, Jeffrey E. Rubnitz, Elias Jabbour, Norman J. Lacayo, Vinod A. Pullarkat
Combining venetoclax, a selective BCL2 inhibitor, with low-dose navitoclax, a BCL-XL/BCL2 inhibitor, may allow targeting of both BCL2 and BCL-XL without dose-limiting thrombocytopenia associated with navitoclax monotherapy. The safety and preliminary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e45bfde002b935bce0e2049afbee2a4b
https://doi.org/10.1158/2159-8290.c.6549358.v1
https://doi.org/10.1158/2159-8290.c.6549358.v1
Autor:
Wendy Stock, Thomas B. Alexander, Charles G. Mullighan, Amanda Jacobson, Su Young Kim, Lindsey Rosenwinkel, Deeksha Vishwamitra, Jeremy A. Ross, Yan Sun, John C. Pesko, Bo Tong, Michelle Schmidt, Mohamed Badawi, Chunxu Qu, Yaqi Zhao, Kathryn G. Roberts, Joseph T. Opferman, Robin Norris, Ryan J. Mattison, Shaun A. Fleming, Seong Lin Khaw, Susan I. Colace, Jessica Leonard, Theodore W. Laetsch, Ashish Bajel, Jeffrey E. Rubnitz, Elias Jabbour, Norman J. Lacayo, Vinod A. Pullarkat
Supplementary Data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3a7a73d874845837c5236e29615a265
https://doi.org/10.1158/2159-8290.22540348.v1
https://doi.org/10.1158/2159-8290.22540348.v1
Publikováno v:
Journal of Pediatric Hematology/Oncology. 44:398-401
6-mercaptopurine is a mainstay of acute lymphoblastic leukemia treatment. It has a narrow therapeutic window, dictated by its metabolite, thioguanine and 6-methylmercaptopurine. Skin manifestations usually consist of mild facial rash or hypersensitiv
Autor:
Kurtis J Stocker, Andrew Tiemann, Kelly M Brunk, Bemnat Agegnehu, Kaitlyn Buhlinger, Lindsey Amerine, Megan C Roberts, Jacqueline E McLaughlin, Stephen M Clark, Robert Rose, Befikadu Mekonnen, Nickhill Bhakta, Atalay Mulu Fentie, Thomas B Alexander, Sachiko Ozawa, Michael Chargualaf, Benyam Muluneh
Publikováno v:
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners.
Background The impact and downstream effects of the chemotherapy supply chain in Ethiopia are not well understood. The purpose of this study was to identify perceived gaps in supply chain and characterize their impact on patient care. Methods A concu
Publikováno v:
Annual Review of Cancer Biology. 5:95-117
Childhood hematological malignancies (HM) exhibit profound genetic and biological heterogeneity. Many sporadic and familial HM have a heritable predisposition. Genomic sequencing has revised the taxonomy of lymphoid and myeloid leukemias, indicating