Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Thomas Arnhold"'
Autor:
Arnhold, Thomas (1635–1698)
Publikováno v:
Biblioteka Uniwersytecka we Wrocławiu.
Publikováno v:
International Journal of Mass Spectrometry. 296:1-9
The evaluation of ADME properties contributes importantly to drug candidate selection and therefore is crucial for the drug discovery process. Providing a sufficiently high-throughput capability in laboratories dedicated to early pharmacokinetic stud
Autor:
Thomas Arnhold, Dooti Roy, Christophe Le Tourneau, Francesco Ricci, Christoph Rummelt, O. Fietz, Rainer Claus, Ralph Fritsch, Zohra Oum'Hamed, Björn Hackanson
Publikováno v:
Journal of Clinical Oncology. 36:12024-12024
12024Background: VEGF and Ang-2 inhibitors have demonstrated clinical activity in various tumor types. Given the overlap of the VEGF/VEGFR2 and Ang-2/Tie-2 signaling pathways there is a rationale f...
Autor:
Ralph Fritsch, Björn Hackanson, Heiko G. Niessen, Thomas Arnhold, Christophe Le Tourneau, Rainer Claus, Francesco Ricci, Ulrich Kunz, Elena Elez, Ralph Graeser, Josep Tabernero, Sascha Keller, Nicolas Isambert
Publikováno v:
Journal of Clinical Oncology. 36:2523-2523
2523Background: BI 836880 (q3w or qw, iv) was evaluated in two first-in-human, Phase I trials in pts with advanced/metastatic solid tumors. We report exploratory PK/PD analysis of these studies to ...
Publikováno v:
Travel & Leisure; Sep2024, Vol. 54 Issue 8, p104-104, 1p, 2 Color Photographs
Publikováno v:
European Journal of Pharmaceutical Sciences. 24:451-463
In the early phases of current pharmaceutical research projects, huge numbers of compounds are tested on their biological activity with respect to a certain target by experimental or virtual screening campaigns. To reduce the attrition rate in later
Publikováno v:
Journal of Computer-Aided Molecular Design. 19:189-201
The cytochrome P450 (CYP) enzyme superfamily plays a major role in the metabolism of commercially available drugs. Inhibition of these enzymes by a drug may result in a plasma level increase of another drug, thus leading to unwanted drug-drug interac
In der Reihe'Sprechwissenschaft & Psycholinguistik'werden aktuelle Beiträge zur Erforschung von Sprachprozessen publiziert.Einen Schwerpunkt des fünften Bandes bildet das Thema'Dysgrammatismus'. Weitere Forschungsbeiträge beziehen sich auf die The
Publikováno v:
The Journal of Nutrition. 132:197-203
Vitamin A is a well-established teratogen in all animal species. A number of case reports also suggest a teratogenic potential of vitamin A in humans. A possible teratogenic risk of dietary liver vitamin A intake, the kinetics of vitamin A and its me
Publikováno v:
Journal of biomolecular screening. 16(3)
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG geförderten) Allianz- bzw. Nationallizenz frei zugänglich. This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national