Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Thomas Andl"'
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 5 (2023)
ABSTRACT Lysyl-diacylglycerol (Lys-DAG) was identified three decades ago in Mycobacterium phlei, but the biosynthetic pathway and function of this aminoacylated lipid have since remained uncharacterized. Combining genetic methods, mass spectrometry,
Externí odkaz:
https://doaj.org/article/29c7be3fddfa4fee9bd5d260da6ee56e
Autor:
Kavya Ganapathy, Christopher Ngo, Thomas Andl, Domenico Coppola, Jong Park, Ratna Chakrabarti
Publikováno v:
Molecular Oncology, Vol 16, Iss 16, Pp 2936-2958 (2022)
Prostate cancer (PCa) progression relies on androgen receptor (AR) function, making AR a top candidate for PCa therapy. However, development of drug resistance is common, which eventually leads to development of castration‐resistant PCa. This warra
Externí odkaz:
https://doaj.org/article/b3ea6c23bd05461588e3fe5f872252a4
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract The purpose of this study is to provide an increased understanding of the molecular mechanisms responsible for mammalian polyamine transport, a process that has been a long-standing ‘black box’ for the polyamine field. Here, we describe
Externí odkaz:
https://doaj.org/article/7bcd694c4168484d9a118697e8039c68
Autor:
Cong Lv, Fengyin Li, Xiang Li, Yuhua Tian, Yue Zhang, Xiaole Sheng, Yongli Song, Qingyong Meng, Shukai Yuan, Liming Luan, Thomas Andl, Xu Feng, Baowei Jiao, Mingang Xu, Maksim V. Plikus, Xing Dai, Christopher Lengner, Wei Cui, Fazheng Ren, Jianwei Shuai, Sarah E. Millar, Zhengquan Yu
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-4 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/e76adeb2c76c4a8e8ca468d031d7f0ae
Autor:
Alexia Bossan, Richard Ottman, Thomas Andl, Md Faqrul Hasan, Nupam Mahajan, Domenico Coppola, Ratna Chakrabarti
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-13 (2018)
Abstract Background FGD4 (Frabin) is an F-actin binding protein with GTP/GDP exchange activity specific for CDC42. It is involved in reorganization of the actin cytoskeleton, which requires both actin binding and CDC42 activating function of FGD4. Ex
Externí odkaz:
https://doaj.org/article/32cb2fa058ad4da0aa71e728d06ddd6e
Autor:
Cong Lv, Fengyin Li, Xiang Li, Yuhua Tian, Yue Zhang, Xiaole Sheng, Yongli Song, Qingyong Meng, Shukai Yuan, Liming Luan, Thomas Andl, Xu Feng, Baowei Jiao, Mingang Xu, Maksim V. Plikus, Xing Dai, Christopher Lengner, Wei Cui, Fazheng Ren, Jianwei Shuai, Sarah E. Millar, Zhengquan Yu
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-18 (2017)
MicroRNAs play an important role in stem cell fate and tumorigenesis. In this work, the authors show that miR-31 controls mammary stem cell self-renewal and tumorigenesis by simultaneously activating Wnt/β-catenin and repressing TGFβ signaling path
Externí odkaz:
https://doaj.org/article/ca55349c2f9c4d529171e92fed21d469
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Tumor cells reside in a highly complex and heterogeneous tumor microenvironment (TME), which is composed of a myriad of genetically stable non-cancer cells, including fibroblasts, immune cells, endothelial cells, and epithelial cells, and a tumor-spe
Externí odkaz:
https://doaj.org/article/06623a80df104bccbcdb7a66edae4142
Autor:
Yuhua Tian, Xianghui Ma, Cong Lv, Xiaole Sheng, Xiang Li, Ran Zhao, Yongli Song, Thomas Andl, Maksim V Plikus, Jinyue Sun, Fazheng Ren, Jianwei Shuai, Christopher J Lengner, Wei Cui, Zhengquan Yu
Publikováno v:
eLife, Vol 6 (2017)
Intestinal regeneration and tumorigenesis are believed to be driven by intestinal stem cells (ISCs). Elucidating mechanisms underlying ISC activation during regeneration and tumorigenesis can help uncover the underlying principles of intestinal homeo
Externí odkaz:
https://doaj.org/article/1d2bccaaafe9496e8e76507d170d4c34
Autor:
Mikaeel Young, Ali Ozcan, Briana Lee, Tyler Maxwell, Thomas Andl, Parthiban Rajasekaran, Melanie J. Beazley, Laurene Tetard, Swadeshmukul Santra
Publikováno v:
Pathogens, Vol 8, Iss 3, p 120 (2019)
Nosocomial infections pose serious health concerns with over 2 million reported annually in the United States. Many of these infections are associated with bacterial resistance to antibiotics and hence, alternative treatments are critically needed. T
Externí odkaz:
https://doaj.org/article/5b90b1a22fd244209f3ae932f2e2c363
Autor:
Linli Zhou, Mingang Xu, Yongguang Yang, Kun Yang, Randall R Wickett, Thomas Andl, Sarah E Millar, Yuhang Zhang
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0160425 (2016)
The hair follicle dermal papilla (DP) contains a unique prominin-1/CD133-positive (CD133+) cell subpopulation, which has been shown to possess hair follicle-inducing capability. By assaying for endogenous CD133 expression and performing lineage traci
Externí odkaz:
https://doaj.org/article/8db6bb1964b743b18022b50fd13b8016