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pro vyhledávání: '"Thomas Alexander Packard"'
Autor:
Thomas Alexander Packard, Eytan Herzig, Xiaoyu Luo, Johanne H Egedal, Zachary W Grimmett, Kim J Hasenkrug, Nadia Roan, Warner C Greene
Publikováno v:
The Journal of Immunology. 202:197.2-197.2
Seeding of the latent HIV reservoir occurs quickly within hours to a few days after initial viral infection. It is the persistence of virus within this reservoir that thwarts an HIV cure and necessitates life-long antiretroviral therapy (ART). Centra
Autor:
Thomas Alexander Packard, Xiaoyu Luo, Zachary W. Grimmett, Eytan Herzig, Nadia R. Roan, Warner C. Greene
Publikováno v:
The Journal of Immunology. 200:182.4-182.4
HIV infection rapidly causes localized inflammation, which contributes to viral pathogenesis by recruiting cells to become infected. At the same time, the stable HIV reservoir forms swiftly and persists over the life of the individual, likely due to
Publikováno v:
The Journal of Immunology. 198:125.1-125.1
HIV-1 infected individuals require lifelong antiretroviral therapy (ART). If ART is discontinued, HIV rebounds from a reservoir of cells containing latent provirus—persistence of this reservoir is the most significant roadblock to curing people inf