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Abstract 1757: Developing sensitive assays to facilitate hit identification of RNA modifying enzymes
Autor:
Grace Boden, Bethany Smith, Rachel Lawrence, Stuart A. Best, Thomas Alanine, Stuart Thomson, Chris Tomlinson, Scott Pollack, Ross Wilkie, Allan M. Jordan, James Wasp, John Unitt
Publikováno v:
Cancer Research. 80:1757-1757
N-6-methyladenosine (m6A) is the most abundant RNA chemical modification found in the eukaryotic transcriptome. It is a dynamic and reversible modification which plays a role in RNA function across a wide range of biological processes. Dysregulation