Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Thomas A. Winters"'
Autor:
Brynn A. Hollingsworth, David R. Cassatt, Andrea L. DiCarlo, Carmen I. Rios, Merriline M. Satyamitra, Thomas A. Winters, Lanyn P. Taliaferro
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Study of the human microbiota has been a centuries-long endeavor, but since the inception of the National Institutes of Health (NIH) Human Microbiome Project in 2007, research has greatly expanded, including the space involving radiation injury. As a
Externí odkaz:
https://doaj.org/article/9324bfec30bb4996b6e7d859dbc67172
Autor:
Merriline M. Satyamitra, David R. Cassatt, Brynn A. Hollingsworth, Paul W. Price, Carmen I. Rios, Lanyn P. Taliaferro, Thomas A. Winters, Andrea L. DiCarlo
Publikováno v:
Metabolites, Vol 10, Iss 8, p 328 (2020)
Triage and medical intervention strategies for unanticipated exposure during a radiation incident benefit from the early, rapid and accurate assessment of dose level. Radiation exposure results in complex and persistent molecular and cellular respons
Externí odkaz:
https://doaj.org/article/775777f338604466b47dc2d7bf3f2bc8
Autor:
Cynthia L. Hendrickson, Shubhadeep Purkayastha, Elzbieta Pastwa, Ronald D. Neumann, Thomas A. Winters
Publikováno v:
Journal of Nucleic Acids, Vol 2010 (2010)
In mammalian cells, DNA double-strand breaks (DSBs) are primarily repaired by nonhomologous end joining (NHEJ). The current model suggests that the Ku 70/80 heterodimer binds to DSB ends and recruits DNA-PKcs to form the active DNA-dependent protein
Externí odkaz:
https://doaj.org/article/00cd3c3a0d2843b5a14bc311c2416c41
Autor:
Carmen I, Rios, Brynn A, Hollingsworth, Andrea L, DiCarlo, John E, Esker, Merriline M, Satyamitra, Toby A, Silverman, Thomas A, Winters, Lanyn P, Taliaferro
Publikováno v:
Radiat Res
Animal models are necessary to demonstrate the efficacy of medical countermeasures (MCM) to mitigate/treat acute radiation syndrome and the delayed effects of acute radiation exposure and develop biodosimetry signatures for use in triage and to guide
Autor:
Merriline M. Satyamitra, Andrea L. DiCarlo, Brynn A. Hollingsworth, Thomas A. Winters, Lanyn P. Taliaferro
Publikováno v:
Radiat Res
Biomarkers are important indicators of biological processes in health or disease. For this reason, they play a critical role in advanced development of radiation biodosimetry tools and medical countermeasures (MCMs). They can aid in the assessment of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2d7990f5ca6a1007f48eb6e484a87ff
https://europepmc.org/articles/PMC9119904/
https://europepmc.org/articles/PMC9119904/
Publikováno v:
Radiat Res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b69e34037bd45a9e6cdfc90a90a2a71
https://europepmc.org/articles/PMC10283012/
https://europepmc.org/articles/PMC10283012/
Autor:
Andrea L. DiCarlo, Lanyn P. Taliaferro, Carmen I. Rios, David R. Cassatt, Brynn A. Hollingsworth, Merriline M. Satyamitra, Paul W. Price, Thomas A. Winters
Publikováno v:
Metabolites, Vol 10, Iss 328, p 328 (2020)
Metabolites
Metabolites
Triage and medical intervention strategies for unanticipated exposure during a radiation incident benefit from the early, rapid and accurate assessment of dose level. Radiation exposure results in complex and persistent molecular and cellular respons
Autor:
Shubhankar Suman, Olga Rodriguez, Kamal Datta, Thomas A. Winters, Chris Albanese, Albert J. Fornace
Publikováno v:
Aging (Albany NY)
Despite recent epidemiological evidences linking radiation exposure and a number of human ailments including cancer, mechanistic understanding of how radiation inflicts long-term changes in cerebral cortex, which regulates important neuronal function
Autor:
Charles W. Loftin, Alexandros G. Georgakilas, Khaled Aziz, Olga A. Sedelnikova, Dave C. Francisco, Jessica M. Hair, Thomas A. Winters, Prakash Peddi, Jennifer S. Dickey, Kara J. Burns, Mihalis I. Panayiotidis, William M. Bonner
Publikováno v:
Free Radical Biology and Medicine. 48:1435-1443
DNA-dependent protein kinase (DNA-PK) is a key non-homologous end joining (NHEJ) nuclear serine/threonine protein kinase involved in various DNA metabolic and damage signaling pathways contributing to the maintenance of genomic stability and preventi
Autor:
Cynthia L. Hendrickson, Elzbieta Pastwa, Ronald D. Neumann, Shubhadeep Purkayastha, Thomas A. Winters
Publikováno v:
Journal of Nucleic Acids, Vol 2010 (2010)
Journal of Nucleic Acids
Journal of Nucleic Acids
In mammalian cells, DNA double-strand breaks (DSBs) are primarily repaired by nonhomologous end joining (NHEJ). The current model suggests that the Ku 70/80 heterodimer binds to DSB ends and recruits DNA-PKcsto form the active DNA-dependent protein k