Zobrazeno 1 - 10
of 294
pro vyhledávání: '"Thomas A. Wilkinson"'
Autor:
Jeffrey M. Bender, Fan Li, Helty Adisetiyo, David Lee, Sara Zabih, Long Hung, Thomas A. Wilkinson, Pia S. Pannaraj, Rosemary C. She, Jennifer Dien Bard, Nicole H. Tobin, Grace M. Aldrovandi
Publikováno v:
Microbiome, Vol 6, Iss 1, Pp 1-12 (2018)
Abstract Background Recent advances in sequencing technologies and bioinformatics tools have allowed for large-scale microbiome studies that are rapidly advancing medical research. However, small changes in technique or analysis can significantly alt
Externí odkaz:
https://doaj.org/article/1fcb9adeddeb440da1607521e2ca87a9
Autor:
Courtney J. Lightfoot, Thomas J. Wilkinson, Gurneet K. Sohansoha, Clare L. Gillies, Noemi Vadaszy, Ella C. Ford, Melanie J. Davies, Thomas Yates, Alice C. Smith, Matthew P. M. Graham-Brown, On behalf of SMILE-K collaborators
Publikováno v:
npj Digital Medicine, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract My Kidneys & Me (MK&M), a digital health intervention delivering specialist health and lifestyle education for people with CKD, was developed and its effects tested (SMILE-K trial, ISRCTN18314195, 18/12/2020). 420 adult patients with CKD sta
Externí odkaz:
https://doaj.org/article/f95c140ae1c4474188f585a61f6ec302
Publikováno v:
BMC Nephrology, Vol 25, Iss 1, Pp 1-13 (2024)
Abstract Background National guidance recognises the key role of rehabilitation in improving outcomes for people living with chronic kidney disease. Implementation of this guidance is reliant upon an adequate and skilled rehabilitation workforce. Dat
Externí odkaz:
https://doaj.org/article/41c43a476de74b4eb26925dd26e1acae
Autor:
Masafumi Horie, Alessandra Castaldi, Mitsuhiro Sunohara, Hongjun Wang, Yanbin Ji, Yixin Liu, Fan Li, Thomas A. Wilkinson, Long Hung, Hua Shen, Hidenori Kage, Ite A. Offringa, Crystal N. Marconett, Per Flodby, Beiyun Zhou, Zea Borok
Publikováno v:
Cells, Vol 9, Iss 11, p 2460 (2020)
Molecular and functional characterization of alveolar epithelial type I (AT1) cells has been challenging due to difficulty in isolating sufficient numbers of viable cells. Here we performed single-cell RNA-sequencing (scRNA-seq) of tdTomato+ cells fr
Externí odkaz:
https://doaj.org/article/ce2fcf11018c4b0d9564c1d239275256
Autor:
Genevieve M. Hilliard, Thomas Stephens Wilkinson, Llinos G. Harris, Rowena E. Jenkins, Laurie P. Shornick
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
IntroductionBacterial infection and biofilm formation contribute to impaired healing in chronic diabetic wounds. Staphylococcus aureus and Pseudomonas aeruginosa are found in human diabetic wound biofilms. They may develop antibiotic resistance, incr
Externí odkaz:
https://doaj.org/article/78945cd3ccf84c09851917dbeee9d652
Autor:
Phillip D. Monk, Jody L. Brookes, Victoria J. Tear, Toby N. Batten, Clare Newall, Marcin Mankowski, Michael G. Crooks, Dave Singh, Rekha Chaudhuri, Brian Leaker, Kerry Lunn, Sophie Reynolds, Sarah Dudley, Felicity J. Gabbay, Stephen T. Holgate, Ratko Djukanovic, Thomas MA Wilkinson
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-17 (2024)
Abstract Background Respiratory viral infections are major drivers of chronic obstructive pulmonary disease (COPD) exacerbations. Interferon-β is naturally produced in response to viral infection, limiting replication. This exploratory study aimed t
Externí odkaz:
https://doaj.org/article/0e45758b1a514217839b388bd5252764
Autor:
Nathan P. Carey, Ffion Curtis, McKenna L. Eisenbeisz, Sadaf Akbari, Meenakshi Sambharia, Diana I. Jalal, Thomas J. Wilkinson
Publikováno v:
The Journal of Clinical Hypertension, Vol 26, Iss 4, Pp 314-329 (2024)
Abstract High blood pressure is an important risk factor for cardiovascular disease and disease progression in chronic kidney disease (CKD). Evidence on the effects of home blood pressure monitoring (HBPM) is limited. This review aimed to determine t
Externí odkaz:
https://doaj.org/article/fabf7887c39d4dcd8fd356de61146379
Autor:
Marvery P. Duarte, Lucas S. Almeida, Silvia G.R. Neri, Juliana S. Oliveira, Thomas J. Wilkinson, Heitor S. Ribeiro, Ricardo M. Lima
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 2, Pp 501-512 (2024)
Abstract Sarcopenia is a risk factor for adverse clinical outcomes in chronic kidney disease (CKD) patients, including mortality. Diagnosis depends on adopted consensus definition and cutoff values; thus, prevalence rates are generally heterogeneous.
Externí odkaz:
https://doaj.org/article/fe1486f834d640e68d91f2f622a5125f
Autor:
Hannah M. L. Young, Ellen M. Castle, Juliet Briggs, Christy Walklin, Roseanne E. Billany, Elham Asgari, Sunil Bhandari, Nicolette Bishop, Kate Bramham, James O. Burton, Jackie Campbell, Joseph Chilcot, Nicola Cooper, Vashist Deelchand, Matthew P. M. Graham-Brown, Lynda Haggis, Alexander Hamilton, Mark Jesky, Philip A. Kalra, Pelagia Koufaki, Jamie Macdonald, Kieran McCafferty, Andrew C. Nixon, Helen Noble, Zoe L. Saynor, Maarten W. Taal, James Tollitt, David C. Wheeler, Thomas J. Wilkinson, Sharlene A. Greenwood
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-21 (2024)
Abstract This trial assessed the feasibility and acceptability of Kidney BEAM, a physical activity and emotional well-being self-management digital health intervention (DHI) for people with chronic kidney disease (CKD), which offers live and on-deman
Externí odkaz:
https://doaj.org/article/929daa35b9e5447792f36af5ef3b5899
Publikováno v:
Physiologia, Vol 3, Iss 3, Pp 451-460 (2023)
Chronic kidney disease (CKD) is characterised by poor physical function. Mechanical muscle properties such as tone, elasticity, and stiffness influence the functional state of the muscle. Measuring these muscle mechanical properties is difficult and
Externí odkaz:
https://doaj.org/article/b9961d68e6b1418bb311bc3e9fe9ca62