Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Thomas A. Werfel"'
Autor:
Niko Hensel, Verena Raker, Benjamin Förthmann, Nora Tula Detering, Sabrina Kubinski, Anna Buch, Georgios Katzilieris-Petras, Julia Spanier, Viktoria Gudi, Sylvia Wagenknecht, Verena Kopfnagel, Thomas Andreas Werfel, Martin Stangel, Andreas Beineke, Ulrich Kalinke, Søren Riis Paludan, Beate Sodeik, Peter Claus
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-15 (2019)
Abstract Background Herpes simplex virus-1 (HSV-1) infections of the central nervous system (CNS) can result in HSV-1 encephalitis (HSE) which is characterized by severe brain damage and long-term disabilities. Different cell types including neurons
Externí odkaz:
https://doaj.org/article/6e9d92d914bf4354b8b0dd0af8a1ce9c
Akademický článek
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Autor:
Mehjabeen Hossain, Suresh P. Sulochana, Katie E. Heath, Saif Mohammad Ishraq Bari, Parker Brewster, Jared Barnes, Azim Munivar, Glenn M. Walker, David A. Puleo, Thomas A. Werfel
Publikováno v:
Journal of Biomedical Materials Research Part A. 111:790-800
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e86a47cb4007e8b68034d7460338dc8
https://doi.org/10.1002/jbm.a.37497
https://doi.org/10.1002/jbm.a.37497
Autor:
Judith De Mel, Mehjabeen Hossain, Oluwaseyi Shofolawe-Bakare, Sk Arif Mohammad, Emily Rasmussen, Khadeeja Milloy, Micaela Shields, Eric W. Roth, Karan Arora, Rafael Cueto, Shou-Ching Tang, John T. Wilson, Adam E. Smith, Thomas A. Werfel
Publikováno v:
Molecular Pharmaceutics. 19:4705-4716
Traditional approaches to vaccines use whole organisms to trigger an immune response, but they do not typically generate robust cellular-mediated immunity and have various safety risks. Subunit vaccines composed of proteins and/or peptides represent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1120953a36b4204ccb0bd6c0533a338b
https://doi.org/10.1021/acs.molpharmaceut.2c00750
https://doi.org/10.1021/acs.molpharmaceut.2c00750
Autor:
Rebecca S. Cook, Dana M. Brantley-Sieders, David L. Elion, Jill M. Pulley, Meghan M. Joly, Robert R. Lavieri, Heidi Hamm, Jae G. Maeng, Matthew T. Duvernay, Wendy E. Bendeman, Bushra Rahman, Donna J. Hicks, Thomas A. Werfel
Although new drug discoveries are revolutionizing cancer treatments, repurposing existing drugs would accelerate the timeline and lower the cost for bringing treatments to cancer patients. Our goal was to repurpose CPI211, a potent and selective anta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::554902981c1ddb8ee844d3b98442fefa
https://doi.org/10.1158/1535-7163.c.6542767
https://doi.org/10.1158/1535-7163.c.6542767
Autor:
Rebecca S. Cook, Dana M. Brantley-Sieders, David L. Elion, Jill M. Pulley, Meghan M. Joly, Robert R. Lavieri, Heidi Hamm, Jae G. Maeng, Matthew T. Duvernay, Wendy E. Bendeman, Bushra Rahman, Donna J. Hicks, Thomas A. Werfel
Flow chart depicting the decision making steps towards selecting TBXA2R as a potential therapeutic target for drug repurposing of CPI211.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c2fc2cb86334453a863d17dd9016ea5
https://doi.org/10.1158/1535-7163.22520773
https://doi.org/10.1158/1535-7163.22520773
Autor:
Rebecca S. Cook, Dana M. Brantley-Sieders, David L. Elion, Jill M. Pulley, Meghan M. Joly, Robert R. Lavieri, Heidi Hamm, Jae G. Maeng, Matthew T. Duvernay, Wendy E. Bendeman, Bushra Rahman, Donna J. Hicks, Thomas A. Werfel
Supplemental Table S1. Kaplan-Meier analysis of clinical cancer expression datasets (RNA-Seq) to assess the relationship between disease free patient survival and TBXA2R expression levels, as determined using Kmplot.com software, using the software-g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::013796120427f7f909528763e42c11cd
https://doi.org/10.1158/1535-7163.22520770.v1
https://doi.org/10.1158/1535-7163.22520770.v1
Autor:
Rebecca S. Cook, Holly K. Koblish, Peggy A. Scherle, Justin M. Balko, Jamaal L. James, Mellissa J. Nixon, Paula I. Gonzales-Ericsson, Violeta Sanchez, Donna J. Hicks, Bushra Rahman, David L. Elion, Thomas A. Werfel
Efferocytosis is the process by which apoptotic cells are cleared from tissue by phagocytic cells. The removal of apoptotic cells prevents them from undergoing secondary necrosis and releasing their inflammation-inducing intracellular contents. Effer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a7c8a9839e99a391d54de44b1f8950a
https://doi.org/10.1158/0008-5472.c.6510818.v1
https://doi.org/10.1158/0008-5472.c.6510818.v1
Autor:
Rebecca S. Cook, Holly K. Koblish, Peggy A. Scherle, Justin M. Balko, Jamaal L. James, Mellissa J. Nixon, Paula I. Gonzales-Ericsson, Violeta Sanchez, Donna J. Hicks, Bushra Rahman, David L. Elion, Thomas A. Werfel
Supplemental Figure S6. Tumors harvested on treatment d 7 were assessed by IHC for FoxP3 and Arg-1. Representative images are shown. Original magnification = 400X. Asterisks represent areas of acellular debris. Black arrows indicate tumor infiltratin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b391b6002fd2de78471ae232ce1fdf3
https://doi.org/10.1158/0008-5472.22421027
https://doi.org/10.1158/0008-5472.22421027
Autor:
Craig L. Duvall, Rebecca S. Cook, Dana M. Brantley-Sieders, Samantha M. Sarett, Somtochukwu C. Dimobi, Kameron V. Kilchrist, Paula Gonzalez Ericsson, Violeta Sanchez, Donna J. Hicks, Linus H. Lee, Meghan Morrison Joly, Taylor E. Kavanaugh, Meredith A. Jackson, Shan Wang, Thomas A. Werfel
Supplemental Figures S1-9 Supplemental Figure S1 - Table of Oligos Supplemental Figures S2-5 - Scheme of chemical synthesis and characterization of polymers Supplemental Figure S6 - Basic in vitro characterization of si-NPs Supplemental Figure S7 - T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f85d61b430296663b3ff687420dc690
https://doi.org/10.1158/0008-5472.22417482.v1
https://doi.org/10.1158/0008-5472.22417482.v1