Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Thomas A. Vida"'
Autor:
Ryder Davidson, Reese I. Krider, Philip Borsellino, Keith Noorda, George Alhwayek, Thomas A. Vida
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 11, Pp 8816-8839 (2023)
Neuroinflammation, a core pathological feature observed in several neurodegenerative diseases, including Alzheimer’s disease (AD), is rapidly gaining attention as a target in understanding the molecular underpinnings of these disorders. Glial cells
Externí odkaz:
https://doaj.org/article/41beca0a9bb64f129382349375589a27
Publikováno v:
Pharmaceuticals, Vol 16, Iss 5, p 742 (2023)
Ketamine is a promising alternative to traditional pharmacotherapies for major depressive disorder, treatment-resistant depression, and other psychiatric conditions that heavily contribute to the global disease burden. In contrast to the current stan
Externí odkaz:
https://doaj.org/article/6be1dd91815b4363b69dcf0a55e50744
Autor:
Neil G. Haycocks, Jessica Hernandez-Moreno, Johan C. Bester, Robert Hernandez, Rosalie Kalili, Daman Samrao, Edward Simanton, Thomas A. Vida
Multiple choice questions (MCQs) are the mainstay of examinations for medical education, physician licensing, and board certification. MCQs are traditionally a preferred way to test rote recall of memorized facts. Their utility in assessing higher co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a05d9cc4a38642ed17b68c4802f03003
https://doi.org/10.21203/rs.3.rs-1965172/v1
https://doi.org/10.21203/rs.3.rs-1965172/v1
Autor:
Andrew J. Bean, Phyllis I. Hanson, Natalie Sirisaengtaksin, Wei Sun, Samuel A. Merrill, Thomas A. Vida
Publikováno v:
Traffic. 11:867-876
The number of surface membrane proteins and their residence time on the plasma membrane are critical determinants of cellular responses to cues that can control plasticity, growth and differentiation. After internalization, the ultimate fate of many
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f9a9fe91400c4d623089c0472604cf2
https://doi.org/10.1111/j.1600-0854.2010.01053.x
https://doi.org/10.1111/j.1600-0854.2010.01053.x
Publikováno v:
Journal of Biological Chemistry. 279:18270-18276
The endosome-associated protein Hrs inhibits the homotypic fusion of early endosomes. A helical region of Hrs containing a Q-SNARE motif mediates this effect as well as its endosomal membrane association via SNAP-25, an endosomal receptor for Hrs. Hr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f2d0df5ec9eb5da3a6e55e042a7c2b7
https://doi.org/10.1074/jbc.m400093200
https://doi.org/10.1074/jbc.m400093200
Publikováno v:
The Journal of Cell Biology
Movement through the endocytic pathway occurs principally via a series of membrane fusion and fission reactions that allow sorting of molecules to be recycled from those to be degraded. Endosome fusion is dependent on SNARE proteins, although the nat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e466cbe8c28d5c9af8dd382bfcccc2ea
https://doi.org/10.1083/jcb.200302083
https://doi.org/10.1083/jcb.200302083
Autor:
Jean-Jacques Panthier, Rashi Gautam, Tamio Suzuki, Thomas A. Vida, Richard A. Spritz, Naoki Oiso, Edward K. Novak, Richard T. Swank, P. G. Suprabha
Publikováno v:
Proceedings of the National Academy of Sciences. 100:1146-1150
In the mouse, more than 16 loci are associated with mutant phenotypes that include defective pigmentation, aberrant targeting of lysosomal enzymes, prolonged bleeding, and immunodeficiency, the result of defective biogenesis of cytoplasmic organelles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db9cc0ebfe8ff86fe2fb0453a03dad22
https://doi.org/10.1073/pnas.0237292100
https://doi.org/10.1073/pnas.0237292100
Autor:
Harnath Shelat, Ta Jen Liu, Michael K. Barnhart, Diane L. Hickman-Bick, Thomas A. Vida, James T. Willerson, Patricia M. Dillard, Pierre Zoldhelyi
Publikováno v:
Circulation. 103:407-414
Background —The transcription factor E2F-1 promotes S-phase entry and death in transformed cells and primary cardiomyocytes. We tested the hypothesis that overexpression of E2F-1 forces growth-arrested human coronary vascular smooth muscle cells (V
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a98c9bb3b8d88f518560a9b24f36777
https://doi.org/10.1161/01.cir.103.3.407
https://doi.org/10.1161/01.cir.103.3.407
Autor:
Brenda Gerhardt, Thomas A. Vida
Publikováno v:
The Journal of Cell Biology
We report a cell-free system that measures transport-coupled maturation of carboxypeptidase Y (CPY). Yeast spheroplasts are lysed by extrusion through polycarbonate filters. After differential centrifugation, a 125,000-g pellet is enriched for radiol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7781e4fa8551e78c9c3a627946238d60
http://europepmc.org/articles/PMC2199724
http://europepmc.org/articles/PMC2199724
Publikováno v:
Journal of Biological Chemistry. 273:15818-15829
Molecular mechanisms of vesicle transport between the prevacuolar compartment and the vacuole in yeast or the lysosome in mammalian cells are poorly understood. To learn more about the specificity of this intercompartmental step, we have examined the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3881445c71c413ac4d80debc24f8c9c
https://doi.org/10.1074/jbc.273.25.15818
https://doi.org/10.1074/jbc.273.25.15818