Zobrazeno 1 - 10
of 373
pro vyhledávání: '"Thomas A. Neff"'
Autor:
Beatrice Beck-Schimmer, Erik Schadde, Urs Pietsch, Miodrag Filipovic, Seraina Dübendorfer-Dalbert, Patricia Fodor, Tobias Hübner, Reto Schuepbach, Peter Steiger, Sascha David, Bernard D. Krüger, Thomas A. Neff, Martin Schläpfer
Publikováno v:
Annals of Intensive Care, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Background This study aimed to assess a potential organ protective effect of volatile sedation in a scenario of severe inflammation with an early cytokine storm (in particular IL-6 elevation) in patients suffering from COVID-19-related lung
Externí odkaz:
https://doaj.org/article/d89388265ddd42139e1b38bce90d61b6
Autor:
Beatrice Beck-Schimmer, Erik Schadde, Urs Pietsch, Miodrag Filipovic, Seraina Dübendorfer-Dalbert, Patricia Fodor, Tobias Hübner, Reto Schuepbach, Peter Steiger, Sascha David, Bernard D. Krüger, Thomas A. Neff, Martin Schläpfer
Publikováno v:
Annals of Intensive Care, Vol 14, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/93ef17fa034548368f8754f8f93593ed
Autor:
Robert Provenzano, Steven Fishbane, Lynda Szczech, Robert Leong, Khalil G. Saikali, Ming Zhong, Tyson T. Lee, Mark T. Houser, Lars Frison, John Houghton, Dustin J. Little, Kin-Hung Peony Yu, Thomas B. Neff
Publikováno v:
Kidney International Reports, Vol 7, Iss 3, Pp 665- (2022)
Externí odkaz:
https://doaj.org/article/1830ee1a2e3b4106adf197ccb3c7ea4a
Autor:
Felix Haussner, Alexander Maitz, Volker Rasche, Andrea Hoffmann, Sonja Braumüller, Ludmila Lupu, Anita Ignatius, Thomas A. Neff, Annette Palmer, Markus Huber-Lang
Publikováno v:
Shock. 58:332-340
Abdominal trauma (AT) is of major global importance, particularly because the civil, terroristic, and military traumatic potential of blast injuries has increased. The consequences of blunt abdominal injuries are highly variable and frequently undere
Autor:
Khalil G. Saikali, Tyson Lee, Lynda A. Szczech, Ming Zhong, Dustin J. Little, John Houghton, Mark T. Houser, Robert Leong, Robert Provenzano, Lars Frison, Thomas B. Neff
Publikováno v:
Clin J Am Soc Nephrol
Background and objectives We evaluated the efficacy and cardiovascular safety of roxadustat versus placebo by analyzing data pooled from three phase 3 studies of roxadustat in patients with non–dialysis-dependent CKD and CKD-related anemia. Design,
Autor:
Charles Bradley, Lona Poole, Robert Leong, Anatole Besarab, Liubov Eremeeva, Lynda A. Szczech, Meraf Eyassu, Thomas B. Neff, Kin-Hung Peony Yu, Evgeny Shutov, Cameron Liu, Robert Provenzano, Gopal Saha, Svitlana Korneyeva
Publikováno v:
Nephrology Dialysis Transplantation. 36:1717-1730
Background We evaluated the efficacy and safety of roxadustat versus epoetin alfa for the treatment of chronic kidney disease-related anemia in patients new to dialysis. Methods HIMALAYAS was a Phase 3, open-label, epoetin alfa-controlled trial. Elig
Autor:
Hans-Christoph Erben, Alexander Dullenkopf, Thomas A. Neff, Marc P. Steurer, Nicole Graf, Ralph Zettl, JoEllen Welter, Florian Hess
Publikováno v:
Archives of Orthopaedic and Trauma Surgery. 142:1817-1822
Accurate identification of patients at risk of blood transfusion can reduce complications and improve institutional resource allocation. Probabilistic models are used to detect risk factors and formulate patient blood management strategies. Whether t
Autor:
James Chou, Thomas B. Neff, James A. Tumlin, Stefan Hemmerich, R. Zabaneh, Robert Provenzano, K. H. Peony Yu
Publikováno v:
Journal of Clinical Pharmacology
Roxadustat (FG‐4592), an oral hypoxia‐inducible factor prolyl hydroxylase inhibitor that stimulates erythropoiesis, was evaluated in a phase 1b study in patients with end‐stage renal disease with anemia on hemodialysis. Seventeen patients, on e
Autor:
David C. Gervasi, Christian H. Kjaergaard, Mitchell C. Brenner, Ingrid Langsetmo, Volkmar Guenzler, Pierre E. Signore, Steve J. Klaus, Guangjie Guo, Ughetta del Balzo, Todd W. Seeley, Gail Walkinshaw, F. Aisha Chow, Thomas B. Neff, Al Y. Lin, David Y. Liu, Lee A. Flippin, Qingjian Wang, Michael P. Arend
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 374:342-353
Anemia of chronic kidney disease (CKD) is a multifactorial disorder caused by impaired erythropoietin (EPO) production and altered iron homeostasis associated with inflammation. Hypoxia-inducible factor (HIF) is a transcription factor that stimulates
Autor:
John M Bonvini, Beatrice Beck-Schimmer, Sonja J Kuhn, Sereina M Graber, Thomas A Neff, Martin Schläpfer
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132165 (2015)
In a recent randomized controlled trial our group has demonstrated in 102 patients that late post-conditioning with sevoflurane performed in the intensive care unit after surgery involving extracorporeal circulation reduced damage to cardiomyocytes e
Externí odkaz:
https://doaj.org/article/5c113e757b5f4855b5c5ca8939ac957c