Zobrazeno 1 - 10
of 449
pro vyhledávání: '"Thomas A. Lutz"'
Autor:
Fabian Wirth, Fabrice D. Heitz, Christine Seeger, Ioana Combaluzier, Karin Breu, Heather C. Denroche, Julien Thevenet, Melania Osto, Paolo Arosio, Julie Kerr-Conte, C. Bruce Verchere, François Pattou, Thomas A. Lutz, Marc Y. Donath, Christoph Hock, Roger M. Nitsch, Jan Grimm
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract In patients with type 2 diabetes, pancreatic beta cells progressively degenerate and gradually lose their ability to produce insulin and regulate blood glucose. Beta cell dysfunction and loss is associated with an accumulation of aggregated
Externí odkaz:
https://doaj.org/article/68eb80d31bdf42208e648a12724a93bf
Autor:
Anne Jomard, Luca Liberale, Petia Doytcheva, Martin F. Reiner, Daniel Müller, Michele Visentin, Marco Bueter, Thomas F. Lüscher, Roberto Vettor, Thomas A. Lutz, Giovanni G. Camici, Elena Osto
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Elevated circulating levels of nutrient-derived trimethylamine N-oxide (TMAO) have been associated with the onset and progression of cardiovascular disease by promoting athero-thrombosis. However, in conditions like bariatric surgery (Roux-e
Externí odkaz:
https://doaj.org/article/e93a9b2b84a647c68ee5749ab71b863c
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 35, Iss 3, Pp 1274-1278 (2021)
Abstract Background Measurement of serum concentrations of insulin‐like growth factor (IGF)‐1 is used to diagnose acromegaly in cats. Hypothesis Changes of body weight do not affect serum concentrations of IGF‐1 in cats. Animals Ten healthy pur
Externí odkaz:
https://doaj.org/article/4f9086e75aa149f5bfbfb1b3b50aec7b
Autor:
Sapon Semsirmboon, Dang Khoa Do Nguyen, Narongsak Chaiyabutr, Sutthasinee Poonyachoti, Thomas A. Lutz, Sumpun Thammacharoen
Publikováno v:
Animals, Vol 13, Iss 6, p 970 (2023)
High ambient temperature (HTa) causes acid–base imbalance and systemic oxidative stress, and this may indirectly affect the mammary gland. Furthermore, HTa induces intracellular oxidative stress, which has been proposed to affect cell metabolism di
Externí odkaz:
https://doaj.org/article/e90b0b8367694fab95c0b6d53165ac14
Autor:
Lavinia Boccia, Tito Borner, Misgana Y. Ghidewon, Patricia Kulka, Chiara Piffaretti, Sarah A. Doebley, Bart C. De Jonghe, Harvey J. Grill, Thomas A. Lutz, Christelle Le Foll
Publikováno v:
Molecular Metabolism, Vol 58, Iss , Pp 101444- (2022)
Objective: The behavioral mechanisms and the neuronal pathways mediated by amylin and its long-acting analog sCT (salmon calcitonin) are not fully understood and it is unclear to what extent sCT and amylin engage overlapping or distinct neuronal subp
Externí odkaz:
https://doaj.org/article/cfa1176f619749acbdf60ef6d374579f
Autor:
Aiman Ismaeil, Daniel Gero, Christina N. Boyle, Daniela Alceste, Osama Taha, Alan C. Spector, Thomas A. Lutz, Marco Bueter
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
BackgroundBariatric surgery alters food preferences in rats and reportedly decreases desire to consume high-fat high-sugar food in humans. The aim of this study was to investigate whether early post-operative exposure to high-fat food could increase
Externí odkaz:
https://doaj.org/article/68288642f7414cb2830fd2def15450ec
Autor:
Eric Zini, Gianfranco Gabai, Elena Salesov, Gabriele Gerardi, Laura Da Dalt, Thomas A. Lutz, Claudia E. Reusch
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 34, Iss 2, Pp 616-625 (2020)
Abstract Background Erythrocytes of diabetic cats have decreased superoxide dismutase activity, possibly indicative of oxidative stress. Hypothesis Erythrocytes of diabetic cats undergo oxidative stress, which is caused by hyperglycemia and hyperlipi
Externí odkaz:
https://doaj.org/article/47b59132ed734c84a853f17c8be24108
Autor:
Erica R. Hendrikse, Tayla A. Rees, Zoe Tasma, Michael L. Garelja, Andrew Siow, Paul W. R. Harris, John B. Pawlak, Kathleen M. Caron, Elizabeth S. Blakeney, Andrew F. Russo, Levi P. Sowers, Thomas A. Lutz, Christelle Le Foll, Christopher S. Walker, Debbie L. Hay
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 24, p 16035 (2022)
Calcitonin gene-related peptide (CGRP) is a key component of migraine pathophysiology, yielding effective migraine therapeutics. CGRP receptors contain a core accessory protein subunit: receptor activity-modifying protein 1 (RAMP1). Understanding of
Externí odkaz:
https://doaj.org/article/19f20e794c5043bbab5b71049db7d12b
Publikováno v:
Metabolites, Vol 12, Iss 1, p 51 (2022)
Amylin and leptin synergistically interact in the arcuate nucleus of the hypothalamus (ARC) to control energy homeostasis. Our previous rodent studies suggested that amylin-induced interleukin-6 release from hypothalamic microglia may modulate leptin
Externí odkaz:
https://doaj.org/article/0df60d139fc94a7eb8e62a03a38f2ca8
Autor:
Amalia Ruiz-Serrano, Christina N. Boyle, Josep M. Monné Rodríguez, Julia Günter, Agnieszka E. Jucht, Svende Pfundstein, Andreas M. Bapst, Thomas A. Lutz, Roland H. Wenger, Carsten C. Scholz
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 3, p 1536 (2022)
Dysregulated energy metabolism is a major contributor to a multitude of pathologies, including obesity and diabetes. Understanding the regulation of metabolic homeostasis is of utmost importance for the identification of therapeutic targets for the t
Externí odkaz:
https://doaj.org/article/c316b0ce60bd44718fa2ef25c687347e