Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Thomas A. Dix"'
Autor:
Tyler C. Beck, Kendra Springs, Jordan E. Morningstar, Catherine Mills, Andrew Stoddard, Lilong Guo, Kelsey Moore, Cortney Gensemer, Rachel Biggs, Taylor Petrucci, Jennie Kwon, Kristina Stayer, Natalie Koren, Jaclyn Dunne, Diana Fulmer, Ayesha Vohra, Le Mai, Sarah Dooley, Julianna Weninger, Yuri Peterson, Patrick Woster, Thomas A. Dix, Russell A. Norris
Publikováno v:
Molecules, Vol 27, Iss 12, p 3678 (2022)
Cancer is the second most common cause of death in the United States, accounting for 602,350 deaths in 2020. Cancer-related death rates have declined by 27% over the past two decades, partially due to the identification of novel anti-cancer drugs. De
Externí odkaz:
https://doaj.org/article/d70ba7eb628844afabcd16e1794602b4
Autor:
Tyler C. Beck, Kyle R. Beck, Calvin B. Holloway, Richard A. Hemings, Thomas A. Dix, Russell A. Norris
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
The emergence of a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2; COVID-19) in China, reported to the World Health Organization on December 31, 2019, has led to a large global pandemic and is a major public health issue. As a result, th
Externí odkaz:
https://doaj.org/article/096e978ee981470fb9040354d3dce47a
Autor:
Jin Hwan Lee, Zheng Z Wei, Wenyuan Cao, Soonmi Won, Xiaohuan Gu, Megan Winter, Thomas A. Dix, Ling Wei, Shan Ping Yu
Publikováno v:
Neurobiology of Disease, Vol 96, Iss , Pp 248-260 (2016)
Stroke is a leading threat to human life and health in the US and around the globe, while very few effective treatments are available for stroke patients. Preclinical and clinical studies have shown that therapeutic hypothermia (TH) is a potential tr
Externí odkaz:
https://doaj.org/article/4f7a9983b5174ff8a0b5f8538d4c73cd
Publikováno v:
Medical Sciences, Vol 7, Iss 9, p 93 (2019)
Kappa-opioid agonists (KOAs) enhance cardiac performance, as well as reduce infarct size and prevent deleterious cardiac remodeling following myocardial infarction. Additionally, KOAs promote diuresis; however, there has been limited development of K
Externí odkaz:
https://doaj.org/article/e4e3c504447d4fc692f222aed5620bbd
Publikováno v:
Pharmaceuticals, Vol 12, Iss 2, p 95 (2019)
Many original research articles have been published that describe findings and outline areas for the development of kappa-opioid agonists (KOAs) as novel drugs; however, a single review article that summarizes the broad potential for KOAs in drug dev
Externí odkaz:
https://doaj.org/article/5a85304f4a0e4938892506030c798b29
Autor:
Thomas C. Dix, Irmgard U. Haussmann, Sarah Brivio, Mohannakarthik P. Nallasivan, Yavor HadzHiev, Ferenc Müller, Berndt Müller, Jonathan Pettitt, Matthias Soller
Publikováno v:
RNA. 28:1377-1390
Cap methyltransferases (CMTrs) O methylate the 2′ position of the ribose (cOMe) of cap-adjacent nucleotides of animal, protist, and viral mRNAs. Animals generally have two CMTrs, whereas trypanosomes have three, and many viruses encode one in their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64925970f0bbb32803cb1e0bcd79b17e
https://doi.org/10.1261/rna.079317.122
https://doi.org/10.1261/rna.079317.122
Autor:
Irmgard U. Haussmann, Thomas C. Dix, Veronica Dezi, Abdullah I. Hans, Roland Arnold, Matthias Soller
SUMMARYSingle guide RNA (sgRNA) directs Cas9 nuclease for gene-specific scission of double-stranded DNA. High Cas9 activity is essential for efficient gene editing to generate gene deletions and gene replacements by homologous recombination. Here we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00cfd65b600ee5adb9f846da79acca80
https://doi.org/10.1101/2022.12.15.520550
https://doi.org/10.1101/2022.12.15.520550
Autor:
Thomas C, Dix, Irmgard U, Haussmann, Sarah, Brivio, Mohannakarthik P, Nallasivan, Yavor, HadzHiev, Ferenc, Müller, Berndt, Müller, Jonathan, Pettitt, Matthias, Soller
Publikováno v:
RNA (New York, N.Y.). 28(10)
Cap methyltransferases (CMTrs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f82908254a434b45540b1aac928fe3dc
https://pubmed.ncbi.nlm.nih.gov/35970556
https://pubmed.ncbi.nlm.nih.gov/35970556
Publikováno v:
Advances in nanomedicine and nanotechnology research. 1(1)
Addiction to conventional opioid pain analgesics is a major societal problem that is increasing at an alarming rate. New drugs to combat the effects of opioid abuse are desperately needed. Kappa-opioid agonists are efficacious in peripheral pain mode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e9ff881ceae47bd25e5651fd453e8a31
https://pubmed.ncbi.nlm.nih.gov/35494408
https://pubmed.ncbi.nlm.nih.gov/35494408
Publikováno v:
Marine Ecology Progress Series. 653:105-119
Capitellid polychaetes are ubiquitous throughout the world’s oceans and are often encountered in high abundance. We used an extensive dataset of species abundance and distribution records of the Capitella capitata complex, C. aciculata, C. jonesi,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e41856eca040fb4843c852ca2a94643b
https://doi.org/10.3354/meps13484
https://doi.org/10.3354/meps13484