Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Thomas A. Darde"'
Autor:
Indusha Kugathas, Hanna K. L. Johansson, Edith Chan Sock Peng, Maryne Toupin, Bertrand Evrard, Thomas A. Darde, Julie Boberg, Monica K. Draskau, Antoine D. Rolland, Séverine Mazaud-Guittot, Frédéric Chalmel, Terje Svingen
Publikováno v:
Kugathas, I, Johansson, H K L, Chan Sock Peng, E, Toupin, M, Evrard, B, Darde, T A, Boberg, J, Draskau, M K, Rolland, A D, Mazaud-Guittot, S, Chalmel, F & Svingen, T 2023, ' Transcriptional profiling of the developing rat ovary following intrauterine exposure to the endocrine disruptors diethylstilbestrol and ketoconazole ', Archives of Toxicology, vol. 97, pp. 849-863 . https://doi.org/10.1007/s00204-023-03442-2
Archives of Toxicology
Archives of Toxicology, 2023, 97 (3), pp.849-863. ⟨10.1007/s00204-023-03442-2⟩
Archives of Toxicology
Archives of Toxicology, 2023, 97 (3), pp.849-863. ⟨10.1007/s00204-023-03442-2⟩
Exposure to endocrine-disrupting chemicals (EDCs) during development may cause reproductive disorders in women. Although female reproductive endpoints are assessed in rodent toxicity studies, a concern is that typical endpoints are not sensitive enou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dc064d00a0564016fb619e64450e33a
https://orbit.dtu.dk/en/publications/3d1771d2-2852-4992-9796-cc5d695b3671
https://orbit.dtu.dk/en/publications/3d1771d2-2852-4992-9796-cc5d695b3671
Autor:
Thomas A Darde, Frédéric Chalmel, Frank Tüttelmann, Jörg Gromoll, Henrike Krenz, Martin Dugas
Publikováno v:
Human Reproduction
Human Reproduction, 2020, 35 (9), pp.1983-1990. ⟨10.1093/humrep/deaa155⟩
Human Reproduction, Oxford University Press (OUP), 2020, 35 (9), pp.1983-1990. ⟨10.1093/humrep/deaa155⟩
Human Reproduction, 2020, 35 (9), pp.1983-1990. ⟨10.1093/humrep/deaa155⟩
Human Reproduction, Oxford University Press (OUP), 2020, 35 (9), pp.1983-1990. ⟨10.1093/humrep/deaa155⟩
STUDY QUESTION How can one design and implement a system that provides a comprehensive overview of research results in the field of epi-/genetics of male infertility and germ cells? SUMMARY ANSWER Working at the interface of literature search engines
Autor:
Nichlas Davidsen, Louise Ramhøj, Claus Asger Lykkebo, Indusha Kugathas, Rikke Poulsen, Anna Kjerstine Rosenmai, Bertrand Evrard, Thomas A. Darde, Marta Axelstad, Martin Iain Bahl, Martin Hansen, Frederic Chalmel, Tine Rask Licht, Terje Svingen
Publikováno v:
Environmental Pollution. 317:120709
PFOS disrupts key developmental pathways during hiPSC-derived cardiomyocyte differentiation in vitro
Autor:
Nichlas Davidsen, Louise Ramhøj, Indusha Kugathas, Bertrand Evrard, Thomas A. Darde, Frédéric Chalmel, Terje Svingen, Anna Kjerstine Rosenmai
Publikováno v:
Davidsen, N, Ramhøj, L, Kugathas, I, Evrard, B, Darde, T A, Chalmel, F, Svingen, T & Rosenmai, A K 2022, ' PFOS disrupts key developmental pathways during hiPSC-derived cardiomyocyte differentiation in vitro ', Toxicology in Vitro, vol. 85, 105475 . https://doi.org/10.1016/j.tiv.2022.105475
Toxicology in Vitro
Toxicology in Vitro, 2022, 85, pp.105475. ⟨10.1016/j.tiv.2022.105475⟩
Toxicology in Vitro
Toxicology in Vitro, 2022, 85, pp.105475. ⟨10.1016/j.tiv.2022.105475⟩
International audience; Exposure to perfluorooctanesulfonic acid (PFOS) has been associated with congenital heart disease (CHD) and decreased birth weight. PFOS exposure can disrupt signaling pathways relevant for cardiac development in stem cell-der
Autor:
Nichlas Davidsen, Louise Ramhøj, Claus Asger Lykkebo, Indusha Kugathas, Rikke Poulsen, Anna Kjerstine Rosenmai, Bertrand Evrard, Thomas A. Darde, Marta Axelstad, Martin Iain Bahl, Martin Hansen, Frederic Chalmel, Tine Rask Licht, Terje Svingen
Publikováno v:
Davidsen, N, Ramhøj, L, Lykkebo, C A, Kugathas, I, Poulsen, R, Rosenmai, A K, Evrard, B, Darde, T A, Axelstad, M, Bahl, M I, Hansen, M, Chalmel, F, Licht, T R & Svingen, T 2022, ' PFOS-induced thyroid hormone system disrupted rats display organ-specific changes in their transcriptomes ', Environmental Pollution, vol. 305, 119340 . https://doi.org/10.1016/j.envpol.2022.119340
Environmental Pollution
Environmental Pollution, 2022, 305, pp.119340. ⟨10.1016/j.envpol.2022.119340⟩
Environmental Pollution
Environmental Pollution, 2022, 305, pp.119340. ⟨10.1016/j.envpol.2022.119340⟩
International audience; Perfluorooctanesulfonic acid (PFOS) is a persistent anthropogenic chemical that can affect the thyroid hormone system in humans and animals. In adults, thyroid hormones (THs) are regulated by the hypothalamic-pituitarythyroid
Autor:
Henrike Krenz, Frank Tüttelmann, Thomas A Darde, Frédéric Chalmel, Joerg Gromoll, Martin Dugas
Interconnecting results of previous OMICs studies is of major importance for identifying novel underlying causes of male infertility. To date, information can be accessed mainly through literature search engines and raw data repositories. However, bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1da2e0d1c707df49513a44db03693c68
https://doi.org/10.1101/2020.02.10.20021790
https://doi.org/10.1101/2020.02.10.20021790
Autor:
Sofie Christiansen, Thomas A Darde, Anne Marie Vinggaard, Camilla Victoria Lindgren Schwartz, Terje Svingen, Frédéric Chalmel
Publikováno v:
Toxicological Sciences
Toxicological Sciences, Oxford University Press (OUP), 2019, 169 (1), pp.303-311. ⟨10.1093/toxsci/kfz046⟩
Toxicological Sciences, 2019, 169 (1), pp.303-311. ⟨10.1093/toxsci/kfz046⟩
Lindgren Schwartz, C V, Vinggaard, A M, Christiansen, S, Darde, T A, Chalmel, F & Svingen, T 2019, ' Distinct transcriptional profiles of the female, male and finasteride-induced feminized male anogenital region in rat fetuses ', Toxicological Sciences, vol. 169, no. 1, pp. 303-311 . https://doi.org/10.1093/toxsci/kfz046
Toxicological Sciences, Oxford University Press (OUP), 2019, 169 (1), pp.303-311. ⟨10.1093/toxsci/kfz046⟩
Toxicological Sciences, 2019, 169 (1), pp.303-311. ⟨10.1093/toxsci/kfz046⟩
Lindgren Schwartz, C V, Vinggaard, A M, Christiansen, S, Darde, T A, Chalmel, F & Svingen, T 2019, ' Distinct transcriptional profiles of the female, male and finasteride-induced feminized male anogenital region in rat fetuses ', Toxicological Sciences, vol. 169, no. 1, pp. 303-311 . https://doi.org/10.1093/toxsci/kfz046
International audience; A short anogenital distance (AGD) in males is a marker for incomplete masculinization and a predictor of adverse effects on male reproductive health. For this reason, AGD is used to assess the endocrine disrupting potential of
Autor:
Nathan Alary, Isabelle Stévant, Aurélie Lardenois, Thomas A Darde, Estelle Lecluze, Frank Tüttelmann, Frédéric Chalmel, Bernard Jégou, Antoine Rolland, Serge Nef, Olivier Collin
Publikováno v:
Bioinformatics
Bioinformatics, 2019, 35 (17), pp.3133-3139. ⟨10.1093/bioinformatics/btz047⟩
Bioinformatics (2019)
Bioinformatics, Oxford University Press (OUP), 2019, 35 (17), pp.3133-3139. ⟨10.1093/bioinformatics/btz047⟩
Bioinformatics, 2019, 35 (17), pp.3133-3139. ⟨10.1093/bioinformatics/btz047⟩
Bioinformatics (2019)
Bioinformatics, Oxford University Press (OUP), 2019, 35 (17), pp.3133-3139. ⟨10.1093/bioinformatics/btz047⟩
MotivationRecent advances in transcriptomics have enabled unprecedented insight into gene expression analysis at a single-cell resolution. While it is anticipated that the number of publications based on such technologies will increase in the next de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a886257e1397d40bf60d96b6e24b057
https://univ-rennes.hal.science/hal-02015545
https://univ-rennes.hal.science/hal-02015545
Autor:
K Bensalah, B Jost, Y Le Bras, Thomas A Darde, C Le Béguec, Nathalie Dejucq-Rainsford, Bernard Jégou, Michael Primig, Antoine Rolland, Frédéric Chalmel, Bertrand Evrard, Sylvain Lavoué
Publikováno v:
Human Reproduction
Human Reproduction, Oxford University Press (OUP), 2019, 34 (7), pp.1278-1290. ⟨10.1093/humrep/dez063⟩
Human Reproduction, 2019, 34 (7), pp.1278-1290. ⟨10.1093/humrep/dez063⟩
Human Reproduction, Oxford University Press (OUP), 2019, 34 (7), pp.1278-1290. ⟨10.1093/humrep/dez063⟩
Human Reproduction, 2019, 34 (7), pp.1278-1290. ⟨10.1093/humrep/dez063⟩
STUDY QUESTION Is the noncoding transcriptional landscape during spermatogenesis conserved between human and rodents? SUMMARY ANSWER We identified a core group of 113 long noncoding RNAs (lncRNAs) and 20 novel genes dynamically and syntenically trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c07136040125e99ceec4b0b78556f37
https://hal-univ-rennes1.archives-ouvertes.fr/hal-02179392
https://hal-univ-rennes1.archives-ouvertes.fr/hal-02179392
Autor:
Rémi Béranger, Séverine Mazaud-Guittot, Olivier Collin, Antoine Rolland, Olivier Sallou, Frédéric Chalmel, Cécile Chevrier, Bernard Jégou, Emmanuelle Becker, Nathalie Bonvallot, Thomas A Darde, Annaëlle Caillarec-Joly, Pierre Gaudriault, Clément Lancien
Publikováno v:
Bioinformatics
Bioinformatics, 2018, 34 (12), pp.2116-2122. ⟨10.1093/bioinformatics/bty040⟩
Bioinformatics, Oxford University Press (OUP), 2018, 34 (12), pp.2116-2122. ⟨10.1093/bioinformatics/bty040⟩
Bioinformatics, 2018, 34 (12), pp.2116-2122. ⟨10.1093/bioinformatics/bty040⟩
Bioinformatics, Oxford University Press (OUP), 2018, 34 (12), pp.2116-2122. ⟨10.1093/bioinformatics/bty040⟩
Motivation At the same time that toxicologists express increasing concern about reproducibility in this field, the development of dedicated databases has already smoothed the path toward improving the storage and exchange of raw toxicogenomic data. N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::564d2cb75a6da04c930816d43d46fe74
https://univ-rennes.hal.science/hal-01863047/document
https://univ-rennes.hal.science/hal-01863047/document