Zobrazeno 1 - 10 of 49 pro vyhledávání: '"Thomas A. Childs"'
1
Akademický článek
Selective breeding for physical inactivity produces cognitive deficits via altered hippocampal mitochondrial and synaptic function
Autor: Nathan R. Kerr, Taylor J. Kelty, Xuansong Mao, Thomas E. Childs, David D. Kline, R. Scott Rector, Frank W. Booth
Publikováno v: Frontiers in Aging Neuroscience, Vol 15 (2023)
Physical inactivity is the 4th leading cause of death globally and has been shown to significantly increase the risk for developing Alzheimer’s Disease (AD). Recent work has demonstrated that exercise prior to breeding produces heritable benefits t
Externí odkaz: https://doaj.org/article/2f613e6b9f704748aee29e529cd6e607
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2
Akademický článek
Acute Wheel-Running Increases Markers of Stress and Aversion-Related Signaling in the Basolateral Amygdala of Male Rats
Autor: Kolter B. Grigsby, Nathan R. Kerr, Taylor J. Kelty, Xuansong Mao, Thomas E. Childs, Frank W. Booth
Publikováno v: Journal of Functional Morphology and Kinesiology, Vol 8, Iss 1, p 6 (2022)
Physical activity (PA) is a non-invasive, cost-effective means of reducing chronic disease. Most US citizens fail to meet PA guidelines, and individuals experiencing chronic stress are less likely to be physically active. To better understand the bar
Externí odkaz: https://doaj.org/article/a86384a3fe844f21b62938de2a437f98
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3
Resistance-exercise training attenuates LPS-induced astrocyte remodeling and neuroinflammatory cytokine expression in female Wistar rats
Autor: Taylor J. Kelty, Xuansong Mao, Nathan R. Kerr, Thomas E. Childs, Gregory N. Ruegsegger, Frank W. Booth
Publikováno v: Journal of Applied Physiology. 132:317-326
Neuroinflammation is an early detectable marker of mild cognitive impairment, the transition state between normal cognition and dementia. Resistance-exercise training can attenuate the cognitive decline observed in patients with mild cognitive impair
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0f105caedbd96141fe470f9b8f85930
https://doi.org/10.1152/japplphysiol.00571.2021
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4
Transcriptomic analysis reveals novel molecular signaling networks involved in low voluntary running behavior after AP-1 inhibition
Autor: Xuansong Mao, Kolter B. Grigsby, Taylor J. Kelty, Nathan R. Kerr, Thomas E. Childs, Frank W. Booth
Publikováno v: Neuroscience. 509
Understanding the neuro-molecular mechanisms that mediate the quantity of daily physical activity (PA) level is of medical significance, given the tremendous health benefits associated with greater physical activity. Here, we examined the effects of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dabf5d3f71479379bc7f5af1af03794d
https://pubmed.ncbi.nlm.nih.gov/36395916
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5
Creatine Supplementation Upregulates mTORC1 Signaling and Markers of Synaptic Plasticity in the Dentate Gyrus While Ameliorating LPS-Induced Cognitive Impairment in Female Rats
Autor: Frank W. Booth, Xuansong Mao, Thomas E. Childs, Michael D. Roberts, Nathan R. Kerr, Taylor J. Kelty
Publikováno v: Nutrients, Vol 13, Iss 2758, p 2758 (2021)
Nutrients
Volume 13
Issue 8
Mild cognitive impairment (MCI) designates the boundary area between cognitive function in natural aging and dementia, and this is viewed as a therapeutic window to prevent the occurrence of dementia. The current study investigated the neurocognitive
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84fae484a20ef20c9bfc2e5a099d422f
https://www.mdpi.com/2072-6643/13/8/2758
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7
Resistance-exercise training ameliorates LPS-induced cognitive impairment concurrent with molecular signaling changes in the rat dentate gyrus
Autor: Kolter B. Grigsby, Christian K. Roberts, Frank W. Booth, Rachel A. Richardson, T. Dylan Olver, Taylor J. Kelty, Xuansong Mao, Paige N. Michener, Thomas E. Childs, Todd R. Schachtman
Publikováno v: Journal of Applied Physiology. 127:254-263
Effective treatments preventing brain neuroinflammatory diseases are lacking. Resistance-exercise training (RT) ameliorates mild cognitive impairment (MCI), a forerunner to neuroinflammatory diseases. However, few studies have addressed the molecular
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fc1aafd4a17edf7337197421e1ee2b0
https://doi.org/10.1152/japplphysiol.00249.2019
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8
A Non-linear approach to dynamic torque modelling for expedited engine characterisation, control and calibration
Autor: Byron Mason, Kambiz Ebrahimi, Mark Cary, Mohammadjavad Ghomashi, Thomas G. Childs
Publikováno v: IFAC-PapersOnLine. 52:661-666
Traditional approaches to engine torque mapping apply steady or quasi-steady-state approaches for data collection. Engine actuators are moved to some set-point and the engine is left to stabilise. Data is then recorded at fixed actuator settings over
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c8cf759fd2c0345d10eaedf4652cb074
https://doi.org/10.1016/j.ifacol.2019.09.105
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9
Three Pattern Recognition Approaches to the Reduction of Vehicle Driving Cycles
Autor: Byron Mason, Thomas G. Childs, Barnaby Coates, Mark Cary, Samuel Le Corre
Publikováno v: ASME 2020 Internal Combustion Engine Division Fall Technical Conference.
Vehicle type approval drive cycles have become a mainstay for benchmarking performance of engines in the development cycle. However, they are typically long and costly to test, with questions of repeatability and real-world relevance. With the move t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8f45fc8816c6745e2b6d662ce19fc490
https://doi.org/10.1115/icef2020-2955
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