Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Thomas A. Bicsak"'
Autor:
Robert R Henry, Juan P Frias, Brandon Walsh, Sharon Skare, John Hemming, Colleen Burns, Thomas A Bicsak, Alain Baron, Mark Fineman
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0203946 (2018)
OBJECTIVE:Metformin use is restricted in patients with renal impairment due to potential excess systemic accumulation. This study evaluated the glycemic effects and safety of metformin delayed-release (Metformin DR), which targets metformin delivery
Externí odkaz:
https://doaj.org/article/aa9b0c1870fa4d97b5a22f5e7b8c61fe
Publikováno v:
Metabolism. 65:20-29
Although metformin has become a drug of choice for the treatment of type 2 diabetes mellitus, some patients may not receive it owing to the risk of lactic acidosis. Metformin, along with other drugs in the biguanide class, increases plasma lactate le
Publikováno v:
Diabetes, Obesity and Metabolism. 19:1499-1501
The history of Metformin-Associated Lactic Acidosis (MALA) is rooted in the earlier experience with phenformin, another biguanide treatment for type 2 diabetes that was removed from the market owing to a clear causal association with cases of lactic
Autor:
Thomas A. Bicsak, Brandon Walsh, Mark Fineman, Juan P. Frias, Sharon Skare, Colleen Burns, John Hemming, Alain D. Baron, Robert R. Henry
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0203946 (2018)
PLoS ONE
PLoS ONE
Objective Metformin use is restricted in patients with renal impairment due to potential excess systemic accumulation. This study evaluated the glycemic effects and safety of metformin delayed-release (Metformin DR), which targets metformin delivery
Publikováno v:
Diabetes, Obesity & Metabolism
Aims Metformin is renally excreted and has been associated with the development of lactic acidosis. Although current advice is to omit metformin during illnesses that may increase the risk of acute kidney injury (AKI), the evidence supporting this is
Publikováno v:
Metabolism. 65:1432-1433
Publikováno v:
Experimental Biology and Medicine. 198:500-512
Until the 1920s, it was assumed that the sole gonadal hormones modulating anterior pituitary glandular secretions were lipid-soluble entities called steroids. Experimental evidence then surfaced during the ensuing decade that demonstrated that the te
Publikováno v:
Biology of Reproduction. 44:599-603
The effects of an insulin-like growth factor-binding protein (IGF-BP) on rat follicular function were examined by using the technique of ovarian intrabursal (IB) injection. Immature female rats were injected with 15 IU of eCG followed immediately wit
Publikováno v:
Analytical Biochemistry. 191:75-79
The possibility that sodium dodecyl sulfate (SDS)-stable complexes of insulin-like growth factor I (IGF-I) and its binding proteins (IGF-BP) exist in rat serum has been examined by using SDS-polyacrylamide gel electrophoresis (PAGE) followed by both
Publikováno v:
Endocrinology. 126:2184-2189
The effects of insulin-like growth factor binding proteins (IGF-BPs) purified from porcine follicular fluid on granulosa cell function were examined using serum-free cultures of rat granulosa cells obtained from immature, diethylstilbestrol-treated r