Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Thomas A. Brodie"'
Autor:
Thomas L. Brodie
Publikováno v:
The Cambridge Companion to the Bible and Literature ISBN: 9781108386081
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d7aeba776cbf1399d455d6d224ec701
https://doi.org/10.1017/9781108386081.003
https://doi.org/10.1017/9781108386081.003
Publikováno v:
Toxicologic Pathology. 38:1051-1057
Anomalies of renal development comprise abnormalities in the amount of renal tissue (agenesis and hypoplasia); anomalies of renal position, form, and orientation; and renal dysplasia. There are previous reports of canine renal dysplasia in different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::802ef4d44ff6bc6c371dbc5a1d9d4da8
https://doi.org/10.1177/0192623310382558
https://doi.org/10.1177/0192623310382558
Autor:
Connie A. Cummings, James Greg Falls, Nancy R. Bordelon, Richard A. Peterson, Thomas A. Brodie, Elizabeth H. Romach, Richard T. Miller, Brenda Faiola
Publikováno v:
Toxicological Sciences. 105:384-394
Therapeutic use of certain peroxisome proliferator-activated receptor (PPAR) alpha agonists (fibrates) for the treatment of dyslipidemia has infrequently been associated with the untoward side effect of myopathy. With interest in PPAR-delta as a ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe7b85eb0c631b90496aab94b750cf89
https://doi.org/10.1093/toxsci/kfn130
https://doi.org/10.1093/toxsci/kfn130
Homeostatic effects of the metalloproteinase disintegrin ADAM15 in degenerative cartilage remodeling
Publikováno v:
Arthritis & Rheumatism. 52:1100-1109
Objective The membrane-anchored metalloproteinase disintegrin ADAM15 is up-regulated in osteoarthritis and has been implicated in proteolysis and cell–matrix interactions. To address its role in cartilage metabolism, we performed an analysis of joi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a65a6f5ff55727a4f04c23e682a9f2b8
https://doi.org/10.1002/art.20974
https://doi.org/10.1002/art.20974
Autor:
Keisuke Horiuchi, Hui Cai, Carl P. Blobel, Klaus T. Preissner, Riccardo Chiusaroli, Roland Baron, Thomas Ludwig, Lawrence G. Lum, Gisela Weskamp, Hans-Peter Hammes, Thomas A. Brodie, Katia Manova
Publikováno v:
Molecular and Cellular Biology. 23:5614-5624
Metalloprotease-disintegrins (ADAMs) are a family of membrane-anchored glycoproteins that are related to snake venom metalloproteases and integrin ligands, termed disintegrins. ADAMs have been implicated in fertilization, myogenesis, neurogenesis, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df273e44174fff9a65e5c6d38a792b0a
https://doi.org/10.1128/mcb.23.16.5614-5624.2003
https://doi.org/10.1128/mcb.23.16.5614-5624.2003
Autor:
Elizabeth J. Beaudet, Ron Laethem, Steven J. Novick, Zhiyang Zhao, Thomas A. Brodie, Debie J. Hoivik, Andrews Robert Carl, Timothy K. Tippin, Edward L. LeCluyse, J. David Becherer, Jürgen M. Lehmann, Linda B. Moore, Darryl L. McDougald, Summer Jolley, Steven A. Kliewer, Michael D. Gaul, G. Hamilton, Kathy Mellon-Kusibab
Publikováno v:
Drug Metabolism and Disposition. 31:870-877
A series of N-hydroxyformamide tumor necrosis factor-alpha converting enzyme (TACE)/matrix metalloprotease (MMP) inhibitors were evaluated for their potential to induce human cytochrome P450 3A (CYP3A). Two in vitro assays were used: 1) a cell-based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::728180f659f051cfc4b785f829bf565b
https://doi.org/10.1124/dmd.31.7.870
https://doi.org/10.1124/dmd.31.7.870
Autor:
Hui Cai, Shigeki Higashyama, Gisela Weskamp, Carl P. Blobel, Thomas A. Brodie, Katia Manova, Thomas Ludwig
Publikováno v:
Molecular and Cellular Biology. 22:1537-1544
MDC9 (ADAM9/meltrin gamma) is a widely expressed and catalytically active metalloprotease-disintegrin protein that has been implicated in the ectodomain cleavage of heparin-binding epidermal growth factor-like growth factor (HB-EGF) and as an alpha s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8961522bedd50521f13187831a168d15
https://doi.org/10.1128/mcb.22.5.1537-1544.2002
https://doi.org/10.1128/mcb.22.5.1537-1544.2002
Autor:
Heather M. Pink, Blair U. Bradford, Thomas A. Brodie, Michael D. Wheeler, Ronald G. Thurman, Xiangli Li, Stephen A. Stimpson, John H. Schwab
Publikováno v:
Infection and Immunity. 69:5883-5891
Peptidoglycan polysaccharide (PG-PS) is a primary structural component of bacterial cell walls and causes rheumatoid-like arthritis in rats. Recently, glycine has been shown to be a potential immunomodulator; therefore, the purpose of this study was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d819fd6506199d1e399db1e858a79297
https://doi.org/10.1128/iai.69.9.5883-5891.2001
https://doi.org/10.1128/iai.69.9.5883-5891.2001
Autor:
Jeffrey L. Selph, Bajin Han, Jeff T. Hutchins, Thomas A. Brodie, R. Christian Crumrine, Stanley D. Chamberlain, Heather M. Pink, Peiyuan Lin, Richard L. Clark, Mandy L. Bergquist, Sarva M. Tadepalli, Stephen A. Stimpson, James G. Conway, Jane G Binz, Scott Depee
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 326(1)
The cFMS (cellular homolog of the V-FMS oncogene product of the Susan McDonough strain of feline sarcoma virus) (Proc Natl Acad Sci U S A 83:3331-3335, 1986) kinase inhibitor 5-(3-methoxy-4-((4-methoxybenzyl)oxy)benzyl)pyrimidine-2,4-diamine (GW2580)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e5dfac8d91c2041aeb5342ba008da63
https://pubmed.ncbi.nlm.nih.gov/18434589
https://pubmed.ncbi.nlm.nih.gov/18434589
Homeostatic effects of the metalloproteinase disintegrin ADAM15 in degenerative cartilage remodeling
Autor:
Beate B, Böhm, Thomas, Aigner, Barbara, Roy, Thomas A, Brodie, Carl P, Blobel, Harald, Burkhardt
Publikováno v:
Arthritis and rheumatism. 52(4)
The membrane-anchored metalloproteinase disintegrin ADAM15 is up-regulated in osteoarthritis and has been implicated in proteolysis and cell-matrix interactions. To address its role in cartilage metabolism, we performed an analysis of joint morpholog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2b0fa62e3332f9622f4ac9643c81564e
https://pubmed.ncbi.nlm.nih.gov/15818704
https://pubmed.ncbi.nlm.nih.gov/15818704