Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Thomas A Szabo-Pardi"'
Publikováno v:
Neural Regeneration Research, Vol 16, Iss 6, Pp 1202-1203 (2021)
Externí odkaz:
https://doaj.org/article/cb75296c8ff742fca784bbf7dfbb24ea
Autor:
Shevon N. Alexander, Audrey R. Green, Emily K. Debner, Lindsey E. Ramos Freitas, Hanna M. K. Abdelhadi, Thomas A. Szabo-Pardi, Michael D. Burton
Publikováno v:
Biology of Sex Differences, Vol 15, Iss 1, Pp 1-25 (2024)
Abstract With the National Institutes of Health’s mandate to consider sex as a biological variable (SABV), there has been a significant increase of studies utilizing both sexes. Historically, we have known that biological sex and hormones influence
Externí odkaz:
https://doaj.org/article/fe6f313b62f842c7b5d65112df6b1719
Publikováno v:
Molecular pain.
Fibromyalgia (FM) is a chronic musculoskeletal pain disorder primarily diagnosed in women. Historically, clinical literature focusing on cytokines and immune cells has been inconsistent. However, recent key studies show several layers of immune syste
Publikováno v:
Neuropharmacology. 225
Pain sensitization is a phenomenon that occurs to protect tissues from damage and recent studies have shown how a variety of non-noxious stimuli included in our everyday lives can lead to pain sensitization. Consumption of large amounts of alcohol ov
Autor:
Michael D. Burton, Eric D. Ramirez, Timothy A. McDougal, Grishma Pradhan, Gregory Dussor, Emma Wentworth, Thomas A. Szabo-Pardi, Kufreobong E. Inyang, Theodore J. Price
Publikováno v:
The Journal of Pharmacology and Experimental Therapeutics
AMP-activated protein kinase (AMPK) is a multifunctional kinase that negatively regulates the mechanistic target of rapamycin (mTOR) and mitogen-activated protein kinase (MAPK) signaling, two signaling pathways linked to pain promotion after injury,
Autor:
Timothy A. McDougal, Kufreobong E. Inyang, Thomas A. Szabo-Pardi, Emma Wentworth, Theodore J. Price, Michael D. Burton, Gregory Dussor
Publikováno v:
Pharmacological Research. 139:1-16
Metformin is a widely prescribed drug used in the treatment of type II diabetes. While the drug has many mechanisms of action, most of these converge on AMP activated protein kinase (AMPK), which metformin activates. AMPK is a multifunctional kinase
Publikováno v:
Brain Behav Immun
Recent studies have brought to light the necessity to discern sex-specific differences in various pain states and different cell-types that mediate these differences. These studies have uncovered the role of neuroimmune interactions to mediate pain s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d3012909fd840bff086aff055244af8
https://europepmc.org/articles/PMC8453057/
https://europepmc.org/articles/PMC8453057/
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, Vol 12 (2021)
Chemotherapy-induced peripheral neuropathy (CIPN) is a major dose-limiting side effect that occurs in up to 63% of patients and has no known effective treatment. A majority of studies do not effectively assess sex differences in the onset and persist
Publikováno v:
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Peripheral nerve injury induces a myriad of immune symptoms that impacts pain and overall quality of life. Recent studies have revealed neuroimmune interactions in various pain states are important to mediate sex differences in their etiology. A desc
Publikováno v:
J Neurosci Methods
Background Neuroimmunologists aspire to understand the interactions between neurons, microglia, and astrocytes in the CNS. To study these cells, researchers work with either immortalized cell lines or primary cells acquired from animal tissue. Primar