Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Thomas A Summers"'
Autor:
Priya Balasubramanian, James C Lang, Kris R Jatana, Brandon Miller, Enver Ozer, Mathew Old, David E Schuller, Amit Agrawal, Theodoros N Teknos, Thomas A Summers, Maryam B Lustberg, Maciej Zborowski, Jeffrey J Chalmers
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e42048 (2012)
Epithelial to mesenchymal transition (EMT) has been hypothesized as a mechanism by which cells change phenotype during carcinogenesis, as well as tumor metastasis. Whether EMT is involved in cancer metastasis has a specific, practical impact on the f
Externí odkaz:
https://doaj.org/article/b8ae65deab954561b0fc79533230b97f
Publikováno v:
Journal of Chemical Information and Modeling. 63:2699-2706
RRx-001 Radioprotection: Enhancement of Survival and Hematopoietic Recovery in Gamma-Irradiated Mice
Autor:
Kimberly J. Jurgensen, William K. J. Skinner, Bryan Oronsky, Nacer D. Abrouk, Andrew E. Graff, Reid D. Landes, William E. Culp, Thomas A. Summers, Lynnette H. Cary
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
The present studies evaluate the in vivo prophylactic radioprotective effects of 1-bromoacetyl-3, 3-dinitroazetidine (RRx-001), a phase III anticancer agent that inhibits c-myc and downregulates CD-47, after total body irradiation (TBI), in lethally
Externí odkaz:
https://doaj.org/article/07bf6d1f47074698979c2b0221d0f085
Autor:
Joseph M Unger, Lu Qian, Mary W Redman, Susan S Tavernier, Lori Minasian, Ellen V Sigal, Vassiliki A Papadimitrakopoulou, Michael Leblanc, Charles S Cleeland, Samuel A Dzingle, Thomas J Summers, Herta Chao, Sheshadri Madhusudhana, Liza Villaruz, Jeffrey Crawford, Jhanelle E Gray, Karen L Kelly, David R Gandara, Lyudmila Bazhenova, Roy S Herbst, Scott N Gettinger, Carol M Moinpour
Publikováno v:
JNCI: Journal of the National Cancer Institute. 115:437-446
Background An important issue for patients with cancer treated with novel therapeutics is how they weigh the effects of treatment on survival and quality of life (QOL). We compared QOL in patients enrolled to SWOG S1400I, a substudy of the LungMAP bi
Autor:
Christina Brzezniak, Bryan Oronsky, Jane Trepel, Thomas A. Summers Jr., Pedro Cabrales, Min-Jung Lee, Regina Day, Saheli Jha, Scott Caroen, Karen Zeman, Lindsey Ferry, Cindy Harmer, Neil Oronsky, Michelle Lybeck, Harry E. Lybeck, James F. Brown, Tony R. Reid, Corey A. Carter
Publikováno v:
Case Reports in Oncology, Vol 10, Iss 1, Pp 276-280 (2017)
Small cell carcinoma of the vagina is rare, so rare in fact that the total number reported in English-language journals is less than 30. Due to this extremely low incidence, no specific treatment guidelines have been established, and most of what is
Externí odkaz:
https://doaj.org/article/5575e28cae354bda83234f8bdd054988
Autor:
Thomas C. Summers, Terry J. Ord
Publikováno v:
Evolutionary Ecology. 36:701-716
It has been argued that disproportionately larger ornaments in bigger males—positive allometry—is the outcome of sexual selection operating on the size of condition dependent traits. We reviewed the literature and found a general lack of empirica
Autor:
Diem-Trang Pham, Qianyi Cheng, Thomas J. Summers, Nathan J. DeYonker, Dudley K. Kelso, Manuel A. Palma, Charles Edwin Webster
Publikováno v:
Biophys J
To accurately simulate the inner workings of an enzyme active site with quantum mechanics (QM), not only must the reactive species be included in the model but also important surrounding residues, solvent, or coenzymes involved in crafting the microe
Autor:
Danielle A. Klomp, Thomas C. Summers, Indraneil Das, Terry J. Ord, Norhayati Ahmad, Arvin C. Diesmos
Publikováno v:
Ecology Letters. 24:1750-1761
Convergence in communication appears rare compared with other forms of adaptation. This is puzzling, given communication is acutely dependent on the environment and expected to converge in form when animals communicate in similar habitats. We uncover
Publikováno v:
Physical chemistry chemical physics : PCCP. 24(17)
Ligand selectivity to specific lanthanide (Ln) ions is key to the separation of rare earth elements from each other. Ligand selectivity can be quantified with relative stability constants (measured experimentally) or relative binding energies (calcul