Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Thomas A House"'
Autor:
Christopher E Overton, Lorenzo Pellis, Helena B Stage, Francesca Scarabel, Joshua Burton, Christophe Fraser, Ian Hall, Thomas A House, Chris Jewell, Anel Nurtay, Filippo Pagani, Katrina A Lythgoe
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 9, p e1010406 (2022)
The first year of the COVID-19 pandemic put considerable strain on healthcare systems worldwide. In order to predict the effect of the local epidemic on hospital capacity in England, we used a variety of data streams to inform the construction and pa
Externí odkaz:
https://doaj.org/article/14254f9add4d4613988bea8a1292cbaf
Autor:
Alex A Koch, James S Bagnall, Nicola J Smyllie, Nicola Begley, Antony D Adamson, Jennifer L Fribourgh, David G Spiller, Qing-Jun Meng, Carrie L Partch, Korbinian Strimmer, Thomas A House, Michael H Hastings, Andrew SI Loudon
Publikováno v:
eLife, Vol 11 (2022)
The mammalian circadian clock exerts control of daily gene expression through cycles of DNA binding. Here, we develop a quantitative model of how a finite pool of BMAL1 protein can regulate thousands of target sites over daily time scales. We used qu
Externí odkaz:
https://doaj.org/article/12909e7319834f59a2d8e05b4469036f
Autor:
Timothy M Kinyanjui, Thomas A House, Moses C Kiti, Patricia A Cane, David J Nokes, Graham F Medley
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138018 (2015)
Respiratory syncytial virus (RSV) is globally ubiquitous, and infection during the first six months of life is a major risk for severe disease and hospital admission; consequently RSV is the most important viral cause of respiratory morbidity and mor
Externí odkaz:
https://doaj.org/article/bea757965e3142ba8b89431d1cade903
Autor:
Penelope A Hancock, Yasmin Rehman, Ian M Hall, Obaghe Edeghere, Leon Danon, Thomas A House, Matthew J Keeling
Publikováno v:
PLoS Computational Biology, Vol 10, Iss 9, p e1003809 (2014)
Prediction and control of the spread of infectious disease in human populations benefits greatly from our growing capacity to quantify human movement behavior. Here we develop a mathematical model for non-transmissible infections contracted from a lo
Externí odkaz:
https://doaj.org/article/77e028c1a305448d83adb4c5687bddfd
Publikováno v:
Mathematics in Applied Sciences and Engineering. :1-19
In this article, we deal with mild solution of special random impulsive fractional differential equations. Initially, we present the existence of the mild solution via Leray-Schauder fixed point method. After that, we establish the exponential stabil
Autor:
Christopher E. Overton, Lorenzo Pellis, Helena B. Stage, Francesca Scarabel, Joshua Burton, Christophe Fraser, Ian Hall, Thomas A. House, Chris Jewell, Anel Nurtay, Filippo Pagani, Katrina A. Lythgoe
Acknowledgements: The authors would like to thank colleagues in SPI-M-O and JUNIPER consortium for various discussions around hospital modelling and forecasting.
Funder: National Institute for Health Research Health Protection Research Unit (NIH
Funder: National Institute for Health Research Health Protection Research Unit (NIH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64dd08fe3a0355f1bc8e5e455482d624
https://www.repository.cam.ac.uk/handle/1810/341784
https://www.repository.cam.ac.uk/handle/1810/341784
Autor:
James S Bagnall, Alex A Koch, Nicola J Smyllie, Nicola Begley, Antony D Adamson, Jennifer L Fribourgh, David G Spiller, Qing-Jun Meng, Carrie L Partch, Korbinian Strimmer, Thomas A House, Michael H Hastings, Andrew SI Loudon
Publikováno v:
Koch, A, Bagnall, J, Smyllie, N J, Begley, N, Adamson, A, Fribourgh, J L, Spiller, D, Meng, Q-J, Partch, C L, Strimmer, K, House, T, Hastings, M H & Loudon, A 2022, ' Quantification of protein abundance and interaction defines a mechanism for operation of the circadian clock ', eLife, vol. 11, e73976 . https://doi.org/10.7554/eLife.73976
The mammalian circadian clock exerts control of daily gene expression through cycles of DNA binding. Here, we develop a quantitative model of how a finite pool of BMAL1 protein can regulate thousands of target sites over daily time scales. We used qu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bda5ec2b702d72fdf720c555831088b1
https://research.manchester.ac.uk/en/publications/238e144d-a42e-4255-b827-1bca6bd15350
https://research.manchester.ac.uk/en/publications/238e144d-a42e-4255-b827-1bca6bd15350
Autor:
James S Bagnall, Alex A Koch, Nicola J Smyllie, Nicola Begley, Antony D Adamson, Jennifer L Fribourgh, David G Spiller, Qing-Jun Meng, Carrie L Partch, Korbinian Strimmer, Thomas A House, Michael H Hastings, Andrew SI Loudon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d655c11a625b7a52ac09ef266b502c35
https://doi.org/10.7554/elife.73976.sa2
https://doi.org/10.7554/elife.73976.sa2
Autor:
Anthony de Wit, Michael John Cheesman, Benjamin Fisk, Ben Coates, Gregory Richard Hanlon, Thomas Giles House
Publikováno v:
Air Medical Journal
Objective The aeromedical transport of coronavirus patients presents risks to clinicians and aircrew. Patient positioning and physical barriers may provide additional protection during flight. This paper describes airflow testing undertaken on fixed
Publikováno v:
Air Medical Journal. 31:84-86
An intubated prehospital trauma patient was undergoing bag valve mask (BVM) ventilation during a stretcher winch in an AW 139 helicopter. On approach to approximately 50 feet under the rotor disc, the bag valve mask failed, with no adverse outcome. E