Zobrazeno 1 - 10
of 635
pro vyhledávání: '"Thomas A Hope"'
Autor:
Jordyn Silverstein, Wesley Kidder, Susan Fisher, Thomas A Hope, Samantha Maisel, Dianna Ng, Jessica Van Ziffle, Chloe E Atreya, Katherine Van Loon
Publikováno v:
Endocrine Connections, Vol 8, Iss 8, Pp 1149-1158 (2019)
Background: Colorectal carcinoma (CRC) during the peri-partum period is challenging to diagnose due to the overlapping symptoms of CRC and pregnancy. This is the first case series to investigate clinicopathologic, hormonal and molecular features of C
Externí odkaz:
https://doaj.org/article/28f0373f46bc476b9319a892a297865a
Autor:
Mark E. Becker, Laura Martin-Sancho, Lacy M. Simons, Michael D. McRaven, Sumit K. Chanda, Judd F. Hultquist, Thomas J. Hope
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract SARS-CoV-2 initiates infection in the conducting airways, where mucociliary clearance inhibits pathogen penetration. However, it is unclear how mucociliary clearance impacts SARS-CoV-2 spread after infection is established. To investigate vi
Externí odkaz:
https://doaj.org/article/d1189d67a80f4aab97f5f561dc48a2af
Autor:
Jinhee Kim, Deepanwita Bose, Mariluz Araínga, Muhammad R. Haque, Christine M. Fennessey, Rachel A. Caddell, Yanique Thomas, Douglas E. Ferrell, Syed Ali, Emanuelle Grody, Yogesh Goyal, Claudia Cicala, James Arthos, Brandon F. Keele, Monica Vaccari, Ramon Lorenzo-Redondo, Thomas J. Hope, Francois Villinger, Elena Martinelli
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract HIV-1 persistence during ART is due to the establishment of long-lived viral reservoirs in resting immune cells. Using an NHP model of barcoded SIVmac239 intravenous infection and therapeutic dosing of anti-TGFBR1 inhibitor galunisertib (LY2
Externí odkaz:
https://doaj.org/article/fbe3b5ac6da84f6e995899f2ef2ce0bd
Autor:
Jinhee Kim, Deepanwita Bose, Mariluz Araínga, Muhammad R. Haque, Christine M. Fennessey, Rachel A. Caddell, Yanique Thomas, Douglas E. Ferrell, Syed Ali, Emanuelle Grody, Yogesh Goyal, Claudia Cicala, James Arthos, Brandon F. Keele, Monica Vaccari, Ramon Lorenzo-Redondo, Thomas J. Hope, Francois Villinger, Elena Martinelli
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/d4eafc33aa964eaaa8d6b74d7af7c6e2
Autor:
Surekha Yadav, Sarasa T. Kim, Abuzar Moradi Tuchayi, Fei Jiang, Amanda Morley, Rachelle Saelee, Yingbing Wang, Roxanna Juarez, Courtney Lawnh-Heath, Vadim S. Koshkin, Thomas A. Hope
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Purpose68Ga-PSMA-11 is recommended for the selection of patients for treatment in the package insert for 177Lu-PSMA-617. We aimed to compare imaging properties and post-treatment outcomes from radioligand therapy (RLT) of patients selected with 68Ga-
Externí odkaz:
https://doaj.org/article/eb08e626d53d4b5ba812584ec5be6b29
Autor:
Adam White, Margarita Saranti, Artur d’Avila Garcez, Thomas M.H. Hope, Cathy J. Price, Howard Bowman
Publikováno v:
NeuroImage: Clinical, Vol 43, Iss , Pp 103638- (2024)
Machine learning offers great potential for automated prediction of post-stroke symptoms and their response to rehabilitation. Major challenges for this endeavour include the very high dimensionality of neuroimaging data, the relatively small size of
Externí odkaz:
https://doaj.org/article/4b6f9cff20f448b3a8d5726e740ad48e
Publikováno v:
EJNMMI Physics, Vol 9, Iss 1, Pp 1-14 (2022)
Abstract Background The aim of this study is to elucidate the difference in absorbed dose (Dabs) patterns in radiopharmaceutical therapies between alpha emitters (225Ac) and beta emitters (177Lu) when targeting cancer-associated fibroblasts (CAF) or
Externí odkaz:
https://doaj.org/article/0971bc67b4d24f86b19b6b7204be5603
Autor:
Sadia Samer, Yanique Thomas, Mariluz Araínga, Crystal Carter, Lisa M. Shirreff, Muhammad S. Arif, Juan M. Avita, Ines Frank, Michael D. McRaven, Christopher T. Thuruthiyil, Veli B. Heybeli, Meegan R. Anderson, Benjamin Owen, Arsen Gaisin, Deepanwita Bose, Lacy M. Simons, Judd F. Hultquist, James Arthos, Claudia Cicala, Irini Sereti, Philip J. Santangelo, Ramon Lorenzo-Redondo, Thomas J. Hope, Francois J. Villinger, Elena Martinelli
Publikováno v:
JCI Insight, Vol 7, Iss 21 (2023)
TGF-β plays a critical role in maintaining immune cells in a resting state by inhibiting cell activation and proliferation. Resting HIV-1 target cells represent the main cellular reservoir after long-term antiretroviral therapy (ART). We hypothesize
Externí odkaz:
https://doaj.org/article/d91bfe3dac314d9ab922f0f232b2155b
Autor:
LaTonya D Williams, Xiaoying Shen, Sheetal S Sawant, Siriwat Akapirat, Lindsay C Dahora, Matthew Zirui Tay, Sherry Stanfield-Oakley, Saintedym Wills, Derrick Goodman, DeAnna Tenney, Rachel L Spreng, Lu Zhang, Nicole L Yates, David C Montefiori, Michael A Eller, David Easterhoff, Thomas J Hope, Supachai Rerks-Ngarm, Punnee Pittisuttithum, Sorachai Nitayaphan, Jean-Louis Excler, Jerome H Kim, Nelson L Michael, Merlin L Robb, Robert J O'Connell, Nicos Karasavvas, Sandhya Vasan, Guido Ferrari, Georgia D Tomaras, RV305 study team
Publikováno v:
PLoS Pathogens, Vol 19, Iss 5, p e1011359 (2023)
The modestly efficacious HIV-1 vaccine regimen (RV144) conferred 31% vaccine efficacy at 3 years following the four-shot immunization series, coupled with rapid waning of putative immune correlates of decreased infection risk. New strategies to incre
Externí odkaz:
https://doaj.org/article/e0502dca070d4a5f86962367ed6a51ba
Autor:
Lamiaa El-Shennawy, Andrew D. Hoffmann, Nurmaa Khund Dashzeveg, Kathleen M. McAndrews, Paul J. Mehl, Daphne Cornish, Zihao Yu, Valerie L. Tokars, Vlad Nicolaescu, Anastasia Tomatsidou, Chengsheng Mao, Christopher J. Felicelli, Chia-Feng Tsai, Carolina Ostiguin, Yuzhi Jia, Lin Li, Kevin Furlong, Jan Wysocki, Xin Luo, Carolina F. Ruivo, Daniel Batlle, Thomas J. Hope, Yang Shen, Young Kwang Chae, Hui Zhang, Valerie S. LeBleu, Tujin Shi, Suchitra Swaminathan, Yuan Luo, Dominique Missiakas, Glenn C. Randall, Alexis R. Demonbreun, Michael G. Ison, Raghu Kalluri, Deyu Fang, Huiping Liu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
El-Shennawy et al. report that ACE2+ circulating extracellular vesicles (evACE2) are associated with COVID-19 severity and that evACE2 inhibits the infection of SARS-CoV-2 variants of concern at a higher efficacy than soluble ACE2.
Externí odkaz:
https://doaj.org/article/271c6c97f77947d1a54cafa9338a135a