Zobrazeno 1 - 10
of 924
pro vyhledávání: '"Thomas A Cooper"'
Autor:
Manish Jaiswal, Nele A Haelterman, Hector Sandoval, Bo Xiong, Taraka Donti, Auinash Kalsotra, Shinya Yamamoto, Thomas A Cooper, Brett H Graham, Hugo J Bellen
Publikováno v:
PLoS Biology, Vol 16, Iss 3, p e1002622 (2018)
[This corrects the article DOI: 10.1371/journal.pbio.1002197.].
Externí odkaz:
https://doaj.org/article/e772bdd085444f588b496b59bce0221c
Autor:
Amy E Brinegar, Zheng Xia, James Anthony Loehr, Wei Li, George Gerald Rodney, Thomas A Cooper
Publikováno v:
eLife, Vol 6 (2017)
Postnatal development of skeletal muscle is a highly dynamic period of tissue remodeling. Here, we used RNA-seq to identify transcriptome changes from late embryonic to adult mouse muscle and demonstrate that alternative splicing developmental transi
Externí odkaz:
https://doaj.org/article/937ae9dfce8f43faa857a4d762c05add
Autor:
Lathan Lucas, Larissa Nitschke, Brandon Nguyen, James A. Loehr, George G. Rodney, Thomas A. Cooper
Publikováno v:
iScience, Vol 27, Iss 11, Pp 111104- (2024)
Summary: Skeletal muscle cells (myofibers) are elongated non-mitotic, multinucleated syncytia that have adapted a microtubule lattice. Microtubule-associated proteins (MAPs) play roles in regulating microtubule architecture. The most abundant MAP in
Externí odkaz:
https://doaj.org/article/b97167ad0f6049e7a56278c345d0f1e0
Autor:
Manish Jaiswal, Nele A Haelterman, Hector Sandoval, Bo Xiong, Taraka Donti, Auinash Kalsotra, Shinya Yamamoto, Thomas A Cooper, Brett H Graham, Hugo J Bellen
Publikováno v:
PLoS Biology, Vol 13, Iss 7, p e1002197 (2015)
Two insults often underlie a variety of eye diseases including glaucoma, optic atrophy, and retinal degeneration--defects in mitochondrial function and aberrant Rhodopsin trafficking. Although mitochondrial defects are often associated with oxidative
Externí odkaz:
https://doaj.org/article/7b410a2080c44e21a5de764286457421
Publikováno v:
Cell Reports, Vol 24, Iss 1, Pp 197-208 (2018)
Summary: Maintenance of skeletal muscle mass requires a dynamic balance between protein synthesis and tightly controlled protein degradation by the calpain, autophagy-lysosome, and ubiquitin-proteasome systems (proteostasis). Several sensing and gene
Externí odkaz:
https://doaj.org/article/70eda2ff445e4b968516c4b46619bf19
Publikováno v:
Solar Energy. 246:331-342
Autor:
Joshua J. Sharpe, Thomas A. Cooper
Publikováno v:
Genome Biology, Vol 18, Iss 1, Pp 1-4 (2017)
Abstract A new study finds that splicing disruption is a frequent consequence of mutations generated by CRISPR/Cas9 gene-editing technology, and alleles designed to be null can express aberrant proteins. This new information allows enhanced quality c
Externí odkaz:
https://doaj.org/article/8ce378a0626b4be99117d00e7812f4e1
Autor:
Matteo Timpano, Thomas A. Cooper
Publikováno v:
Journal of Solar Energy Engineering. 146
This paper presents a detailed analysis of the optical performance of circular trough concentrators with tubular receivers. First, a simple analytical formula for the achievable geometric concentration ratio as a function of the rim angle and accepta
Publikováno v:
Nucleic acids research.
Loss of gene function can be compensated by paralogs with redundant functions. An example of such compensation are the paralogs of the Muscleblind-Like (MBNL) family of RNA-binding proteins that are sequestered and lose their function in Myotonic Dys
Publikováno v:
Optics express. 30(25)
We present near-ideal axisymmetric numerically optimized spline concentrators (OSCs) which outperform the compound parabolic concentrator (CPC). By perturbing the profile of the revolved CPC by a variable-offset spline defined in tangent-normal space