Zobrazeno 1 - 10
of 132
pro vyhledávání: '"Thomas A Bowden"'
Autor:
Hector Moreno, Alberto Rastrojo, Rhys Pryce, Chiara Fedeli, Gert Zimmer, Thomas A Bowden, Gisa Gerold, Stefan Kunz
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 12, p e0009004 (2020)
A detailed understanding of the mechanisms underlying the capacity of a virus to break the species barrier is crucial for pathogen surveillance and control. New World (NW) mammarenaviruses constitute a diverse group of rodent-borne pathogens that inc
Externí odkaz:
https://doaj.org/article/ba98da8d367242fbb8fb02a727b6c6d6
Autor:
Ilona Rissanen, Robert Stass, Stefanie A Krumm, Jeffrey Seow, Ruben JG Hulswit, Guido C Paesen, Jussi Hepojoki, Olli Vapalahti, Åke Lundkvist, Olivier Reynard, Viktor Volchkov, Katie J Doores, Juha T Huiskonen, Thomas A Bowden
Publikováno v:
eLife, Vol 9 (2020)
The intricate lattice of Gn and Gc glycoprotein spike complexes on the hantavirus envelope facilitates host-cell entry and is the primary target of the neutralizing antibody-mediated immune response. Through study of a neutralizing monoclonal antibod
Externí odkaz:
https://doaj.org/article/a811ae9d2ec64aa9a3922c1b8fc9e42d
Autor:
Neeltje van Doremalen, Teresa Lambe, Sarah Sebastian, Trenton Bushmaker, Robert Fischer, Friederike Feldmann, Elaine Haddock, Michael Letko, Victoria A Avanzato, Ilona Rissanen, Rachel LaCasse, Dana Scott, Thomas A Bowden, Sarah Gilbert, Vincent Munster
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 6, p e0007462 (2019)
Nipah virus (NiV) is a highly pathogenic re-emerging virus that causes outbreaks in South East Asia. Currently, no approved and licensed vaccine or antivirals exist. Here, we investigated the efficacy of ChAdOx1 NiVB, a simian adenovirus-based vaccin
Externí odkaz:
https://doaj.org/article/7353edbe3113432c8b6213e9bf19ade5
Autor:
Pinky Langat, Jayna Raghwani, Gytis Dudas, Thomas A Bowden, Stephanie Edwards, Astrid Gall, Trevor Bedford, Andrew Rambaut, Rodney S Daniels, Colin A Russell, Oliver G Pybus, John McCauley, Paul Kellam, Simon J Watson
Publikováno v:
PLoS Pathogens, Vol 13, Iss 12, p e1006749 (2017)
The global-scale epidemiology and genome-wide evolutionary dynamics of influenza B remain poorly understood compared with influenza A viruses. We compiled a spatio-temporally comprehensive dataset of influenza B viruses, comprising over 2,500 genomes
Externí odkaz:
https://doaj.org/article/0df87b7ba2ac41efb287e9fde55a8c64
Publikováno v:
PLoS Pathogens, Vol 12, Iss 2, p e1005390 (2016)
Externí odkaz:
https://doaj.org/article/9eeabe1e29e14209ae658fce6448dbee
Autor:
Sai Li, Zhaoyang Sun, Rhys Pryce, Marie-Laure Parsy, Sarah K Fehling, Katrin Schlie, C Alistair Siebert, Wolfgang Garten, Thomas A Bowden, Thomas Strecker, Juha T Huiskonen
Publikováno v:
PLoS Pathogens, Vol 12, Iss 2, p e1005418 (2016)
Lassa virus is an enveloped, bi-segmented RNA virus and the most prevalent and fatal of all Old World arenaviruses. Virus entry into the host cell is mediated by a tripartite surface spike complex, which is composed of two viral glycoprotein subunits
Externí odkaz:
https://doaj.org/article/133c23f4ebda413f9c78bf13931d9259
Autor:
Rami Sommerstein, Lukas Flatz, Melissa M Remy, Pauline Malinge, Giovanni Magistrelli, Nicolas Fischer, Mehmet Sahin, Andreas Bergthaler, Sebastien Igonet, Jan Ter Meulen, Dorothée Rigo, Paolo Meda, Nadia Rabah, Bruno Coutard, Thomas A Bowden, Paul-Henri Lambert, Claire-Anne Siegrist, Daniel D Pinschewer
Publikováno v:
PLoS Pathogens, Vol 11, Iss 11, p e1005276 (2015)
Arenaviruses such as Lassa virus (LASV) can cause severe hemorrhagic fever in humans. As a major impediment to vaccine development, delayed and weak neutralizing antibody (nAb) responses represent a unifying characteristic of both natural infection a
Externí odkaz:
https://doaj.org/article/88adfa2938774026b7ab7e3f585a6933
Autor:
Thomas A Bowden, David Bitto, Angela McLees, Christelle Yeromonahos, Richard M Elliott, Juha T Huiskonen
Publikováno v:
PLoS Pathogens, Vol 9, Iss 5, p e1003374 (2013)
The genus Orthobunyavirus within the family Bunyaviridae constitutes an expanding group of emerging viruses, which threaten human and animal health. Despite the medical importance, little is known about orthobunyavirus structure, a prerequisite for u
Externí odkaz:
https://doaj.org/article/e9f93a65ccf540128d40037714277cd7
Autor:
Alice J. Stelfox, Kasopefoluwa Y. Oguntuyo, Ilona Rissanen, Karl Harlos, Robert Rambo, Benhur Lee, Thomas A. Bowden
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT Increased viral surveillance has led to the isolation and identification of numerous uncharacterized paramyxoviruses, rapidly expanding our understanding of paramyxoviral diversity beyond the bounds of known genera. Despite this diversity, a
Externí odkaz:
https://doaj.org/article/92817af984f24736a7422fd40ac06895
Autor:
Daniel Jenkin, Daniel Wright, Pedro M Folegatti, Abigail Platt, Ian Poulton, Alison Lawrie, Nguyen Tran, Amy Boyd, Cheryl Turner, John N Gitonga, Henry K Karanja, Daisy Mugo, Katie J Ewer, Thomas A Bowden, Sarah C Gilbert, Bryan Charleston, Pontiano Kaleebu, Adrian V S Hill, George M Warimwe
Publikováno v:
The Lancet Infectious Diseases.