Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Thomas A Blanpied"'
Autor:
Thomas A Blanpied, Tuo Peter Li
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 8 (2016)
Postsynaptic transmembrane proteins are critical elements of synapses, mediating trans-cellular contact, sensitivity to neurotransmitters and other signaling molecules, and flux of Ca and other ions. Positioning and mobility of each member of this la
Externí odkaz:
https://doaj.org/article/434b276fdd2642b699d5531597d5f856
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36751 (2012)
In neurons, the shape of dendritic spines relates to synapse function, which is rapidly altered during experience-dependent neural plasticity. The small size of spines makes detailed measurement of their morphology in living cells best suited to supe
Externí odkaz:
https://doaj.org/article/b54a937f4f654d01a4cd3e5c04d25d9f
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 14 (2022)
Externí odkaz:
https://doaj.org/article/061532e506fb465b85bc8ac62c2abfb5
Autor:
Deblina Sarkar, Jinyoung Kang, Asmamaw T. Wassie, Margaret E. Schroeder, Zhuyu Peng, Tyler B. Tarr, Ai-Hui Tang, Emily D. Niederst, Jennie Z. Young, Hanquan Su, Demian Park, Peng Yin, Li-Huei Tsai, Thomas A. Blanpied, Edward S. Boyden
Publikováno v:
Nature Biomedical Engineering. 6:1057-1073
Many crowded biomolecular structures in cells and tissues are inaccessible to labelling antibodies. To understand how proteins within these structures are arranged with nanoscale precision therefore requires that these structures be decrowded before
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8df33d3d82665dd042ca169b1106fbba
https://doi.org/10.1038/s41551-022-00912-3
https://doi.org/10.1038/s41551-022-00912-3
Autor:
Charles A, Dean, Sarah R, Metzbower, Scott K, Dessain, Thomas A, Blanpied, David R, Benavides
Publikováno v:
Frontiers in Molecular Neuroscience. 15
The NMDA receptor (NMDAR) subunit GluN1 is critical for receptor function and plays a pivotal role in synaptic plasticity. Mounting evidence has shown that pathogenic autoantibody targeting of the GluN1 subunit of NMDARs, as in anti-NMDAR encephaliti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c24e36603dd5e273e0d46bdb3a0f9108
https://doi.org/10.3389/fnmol.2022.940005
https://doi.org/10.3389/fnmol.2022.940005
Publikováno v:
Methods
Nanoscale distribution of proteins and their relative positioning within a defined subcellular region are key to their physiological functions. Thanks to the super-resolution imaging methods, especially single-molecule localization microscopy (SMLM),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e935991865f3cc4bb1372f40fc51be1
https://doi.org/10.1016/j.ymeth.2019.07.016
https://doi.org/10.1016/j.ymeth.2019.07.016
Autor:
Tony Cijsouw, Austin M. Ramsey, TuKiet T. Lam, Beatrice E. Carbone, Thomas A. Blanpied, Thomas Biederer
Publikováno v:
Proteomes, Vol 6, Iss 4, p 48 (2018)
Synapses are specialized neuronal cell-cell contacts that underlie network communication in the mammalian brain. Across neuronal populations and circuits, a diverse set of synapses is utilized, and they differ in their molecular composition to enable
Externí odkaz:
https://doaj.org/article/016703b1c9de4a5c92371d1900ff022d
Autor:
Ai-Hui Tang, Tara A. LeGates, Xu-Zhuo Gou, Beatrice E. Carbone, Scott M. Thompson, Thomas Biederer, Austin M. Ramsey, Thomas A. Blanpied
Recent evidence suggests that nanoorganization of proteins within synapses may control the strength of communication between neurons in the brain. The unique subsynaptic distribution of glutamate receptors, which cluster in nanoalignment with presyna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f91afd40b242f110103d04405ba5db29
https://doi.org/10.1101/2021.04.30.441835
https://doi.org/10.1101/2021.04.30.441835
We develop methods for investigating protein drift-diffusion dynamics in heterogeneous cell membranes and the roles played by geometry, diffusion, chemical kinetics, and phase separation. Our hybrid stochastic numerical methods combine discrete parti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87edc6b317ed211caec6c5d9eb5ed482
Autor:
Tara A. LeGates, Scott M. Thompson, Austin M. Ramsey, Xu-Zhuo Gou, Thomas A. Blanpied, Ai-Hui Tang, Beatrice E. Carbone, Thomas Biederer
Publikováno v:
Science Advances
The nanoscale distribution of AMPA receptors is under rapid control by adhesion proteins and helps regulate their activation.
Recent evidence suggests that nano-organization of proteins within synapses may control the strength of communication b
Recent evidence suggests that nano-organization of proteins within synapses may control the strength of communication b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe1ae500ed298724144779ae70d214f3
https://pubmed.ncbi.nlm.nih.gov/34417170
https://pubmed.ncbi.nlm.nih.gov/34417170